LncRNA H19 Mitigates Oxidized Low-Density Lipoprotein Induced Pyroptosis via Caspase-1 in Raw 264.7 Cells

Atherosclerosis (AS) is mainly characterized by the activation of inflammatory cells and chronic inflammatory responses after cell injury. Pyroptosis is a form of programmed cell death (PCD) accompanied by the release of inflammatory factors. Many studies have shown that pyroptosis plays an importan...

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Veröffentlicht in:	Inflammation 2021-12, Vol.44 (6), p.2407-2418
Hauptverfasser:	Liu, Shan, Xu, Dong-sheng, Ma, Jiu-long, Huang, Peng, Wu, Di, Ren, Li-qun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Arteriosclerosis Atherosclerosis Atherosclerosis - genetics Atherosclerosis - metabolism Atherosclerosis - pathology Biomedical and Life Sciences Biomedicine Blood vessels Caspase 1 - genetics Caspase 1 - metabolism Caspase-1 Cell activation Cell death Cell injury Chronic illnesses Cytokines Disease Immune system Immunology Inflammation Internal Medicine Lipids Lipoproteins Lipoproteins, LDL - toxicity Low density lipoprotein Macrophages - drug effects Macrophages - metabolism Macrophages - pathology Mice Mitochondria Mitochondria - drug effects Mitochondria - metabolism Mitochondria - pathology NF-kappa B - metabolism NF-κB protein Non-coding RNA Original Article Pathology Pharmacology/Toxicology Pyroptosis Pyroptosis - drug effects RAW 264.7 Cells Reactive oxygen species Reactive Oxygen Species - metabolism Rheumatology RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Signal Transduction Smooth muscle
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