Comparative methylation and RNA-seq expression analysis in CpG context to identify genes involved in Backfat vs. Liver diversification in Nanchukmacdon Pig

Background DNA methylation and demethylation at CpG islands is one of the main regulatory factors that allow cells to respond to different stimuli. These regulatory mechanisms help in developing tissue without affecting the genomic composition or undergoing selection. Liver and backfat play importan...

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Veröffentlicht in:	BMC genomics 2021-11, Vol.22 (1), p.1-801, Article 801
Hauptverfasser:	Arora, Devender, Park, Jong-Eun, Lim, Dajeong, Choi, Bong-Hwan, Cho, In-Cheol, Srikanth, Krishnamoorthy, Kim, Jaebum, Park, Woncheoul
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Biomarkers Biosynthesis Biotechnology & Applied Microbiology Bisulfite Bone morphogenetic proteins Cholesterol Collagen Comparative analysis CpG CpG islands Data analysis DEGs Demethylation Differentiation Diversification DMR DNA methylation Epigenetics Gene expression Gene sequencing Genes Genetic aspects Genetics & Heredity Genomes Genomics Growth Health aspects Identification and classification Immunity Islands Life Sciences & Biomedicine Lipid metabolism Lipids Liver Meat Meat quality Metabolism Methods Methylation Motif Nutritional aspects Ontology Pork Regulatory mechanisms (biology) Reproduction Ribonucleic acid RNA RNA sequencing Science & Technology Signal transduction SIX gene family Swine Swine breeds Tissue culture Tissues Transcription factors
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