P110 Assessing COVID vaccine related side-effects profile and subsequent staff sickness burden in healthcare workers
IntroductionThe COVID19 national immunisation campaign is well underway across the United Kingdom. A large study reported, side-effects from COVID vaccines are moderately frequent, commonly mild and short-lived in a community setting.1 ObjectivesTo examine the side-effects and staff sickness profile...
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| Veröffentlicht in: | Thorax 2021-11, Vol.76 (Suppl 2), p.A126-A127 |
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| description | IntroductionThe COVID19 national immunisation campaign is well underway across the United Kingdom. A large study reported, side-effects from COVID vaccines are moderately frequent, commonly mild and short-lived in a community setting.1 ObjectivesTo examine the side-effects and staff sickness profile from COVID vaccination in healthcare workers and whether the second COVID vaccine dose (VAX2) led to worsening side-effects or sickness burden, compared to the first dose (VAX1).MethodsSelf-reported questionnaire survey to 1500 consecutive healthcare workers (working for 1 NHS Trust) receiving VAX2 at a single central vaccination site from 29/03/2021 to 23/04/2021. VAX1 data was collected at the appointment and VAX2 data asked to be returned via internal mail 7 days later. Responders were asked to grade symptoms (asymptomatic, mild, moderate or severe) & step scores of 0, 1, 2 & 3 allocated correspondingly to estimate side-effect severity changes following VAX2. Data for baseline demographics & sickness burden collected.ResultsThe response rate for VAX1 was 81% (1213) & VAX2 was 31% (464). Matched data was available for 30% (444). There was 81% female preponderance. Median age was 51 (Range 19–74, IQR 18). Most commonly reported side-effect was injection site pain (83%) followed by fatigue (46%), muscle pain (45%), headache (41%), injection site swelling (32%), injection site redness (27%), joint pain (26%), chills (21%) & fever (17%). The frequency of side-effects was similar with no significant severity change after VAX2. Mean duration of side-effects was alike (2.2 days). 3.6% and 5.6% of responders took time (mean) off work for 3.6 and 1.4 days following VAX1 & VAX2 respectively.Abstract P110 Figure 1ConclusionsOur study demonstrated healthcare workers had moderately frequent side-effects, with no significant exacerbation after VAX2. The side-effects burden was short-lived with minimal impact on workforce during resource constrained times, which suggests future booster doses in healthcare workers should remain safe and can be pursued.ReferenceMenni, et al. Vaccine Side-Effects and SARS-CoV-2 Infection after Vaccination in Users of the COVID Symptom Study App in the UK: A Prospective Observational Study. The Lancet Infectious Diseases 2021Apr 27. https://doi.org/10.1016/S1473-3099(21)00224-3 |
| doi_str_mv | 10.1136/thorax-2021-BTSabstracts.219 |
| format | Article |
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A large study reported, side-effects from COVID vaccines are moderately frequent, commonly mild and short-lived in a community setting.1 ObjectivesTo examine the side-effects and staff sickness profile from COVID vaccination in healthcare workers and whether the second COVID vaccine dose (VAX2) led to worsening side-effects or sickness burden, compared to the first dose (VAX1).MethodsSelf-reported questionnaire survey to 1500 consecutive healthcare workers (working for 1 NHS Trust) receiving VAX2 at a single central vaccination site from 29/03/2021 to 23/04/2021. VAX1 data was collected at the appointment and VAX2 data asked to be returned via internal mail 7 days later. Responders were asked to grade symptoms (asymptomatic, mild, moderate or severe) & step scores of 0, 1, 2 & 3 allocated correspondingly to estimate side-effect severity changes following VAX2. Data for baseline demographics & sickness burden collected.ResultsThe response rate for VAX1 was 81% (1213) & VAX2 was 31% (464). Matched data was available for 30% (444). There was 81% female preponderance. Median age was 51 (Range 19–74, IQR 18). Most commonly reported side-effect was injection site pain (83%) followed by fatigue (46%), muscle pain (45%), headache (41%), injection site swelling (32%), injection site redness (27%), joint pain (26%), chills (21%) & fever (17%). The frequency of side-effects was similar with no significant severity change after VAX2. Mean duration of side-effects was alike (2.2 days). 3.6% and 5.6% of responders took time (mean) off work for 3.6 and 1.4 days following VAX1 & VAX2 respectively.Abstract P110 Figure 1ConclusionsOur study demonstrated healthcare workers had moderately frequent side-effects, with no significant exacerbation after VAX2. The side-effects burden was short-lived with minimal impact on workforce during resource constrained times, which suggests future booster doses in healthcare workers should remain safe and can be pursued.ReferenceMenni, et al. Vaccine Side-Effects and SARS-CoV-2 Infection after Vaccination in Users of the COVID Symptom Study App in the UK: A Prospective Observational Study. The Lancet Infectious Diseases 2021Apr 27. https://doi.org/10.1016/S1473-3099(21)00224-3]]></description><identifier>ISSN: 0040-6376</identifier><identifier>EISSN: 1468-3296</identifier><identifier>DOI: 10.1136/thorax-2021-BTSabstracts.219</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Thoracic Society</publisher><subject>COVID-19 vaccines ; Immunization ; Medical personnel ; Pain ; Severe acute respiratory syndrome coronavirus 2 ; The wider impact of the pandemic</subject><ispartof>Thorax, 2021-11, Vol.76 (Suppl 2), p.A126-A127</ispartof><rights>Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2021 Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Muthusami, R</creatorcontrib><creatorcontrib>Adeyeye, S</creatorcontrib><creatorcontrib>Mwale, B</creatorcontrib><creatorcontrib>Rhammaz, S</creatorcontrib><creatorcontrib>Du Rand, M</creatorcontrib><creatorcontrib>Johnson, A</creatorcontrib><creatorcontrib>Du Rand, I</creatorcontrib><title>P110 Assessing COVID vaccine related side-effects profile and subsequent staff sickness burden in healthcare workers</title><title>Thorax</title><addtitle>Thorax</addtitle><description><![CDATA[IntroductionThe COVID19 national immunisation campaign is well underway across the United Kingdom. A large study reported, side-effects from COVID vaccines are moderately frequent, commonly mild and short-lived in a community setting.1 ObjectivesTo examine the side-effects and staff sickness profile from COVID vaccination in healthcare workers and whether the second COVID vaccine dose (VAX2) led to worsening side-effects or sickness burden, compared to the first dose (VAX1).MethodsSelf-reported questionnaire survey to 1500 consecutive healthcare workers (working for 1 NHS Trust) receiving VAX2 at a single central vaccination site from 29/03/2021 to 23/04/2021. VAX1 data was collected at the appointment and VAX2 data asked to be returned via internal mail 7 days later. Responders were asked to grade symptoms (asymptomatic, mild, moderate or severe) & step scores of 0, 1, 2 & 3 allocated correspondingly to estimate side-effect severity changes following VAX2. Data for baseline demographics & sickness burden collected.ResultsThe response rate for VAX1 was 81% (1213) & VAX2 was 31% (464). Matched data was available for 30% (444). There was 81% female preponderance. Median age was 51 (Range 19–74, IQR 18). Most commonly reported side-effect was injection site pain (83%) followed by fatigue (46%), muscle pain (45%), headache (41%), injection site swelling (32%), injection site redness (27%), joint pain (26%), chills (21%) & fever (17%). The frequency of side-effects was similar with no significant severity change after VAX2. Mean duration of side-effects was alike (2.2 days). 3.6% and 5.6% of responders took time (mean) off work for 3.6 and 1.4 days following VAX1 & VAX2 respectively.Abstract P110 Figure 1ConclusionsOur study demonstrated healthcare workers had moderately frequent side-effects, with no significant exacerbation after VAX2. The side-effects burden was short-lived with minimal impact on workforce during resource constrained times, which suggests future booster doses in healthcare workers should remain safe and can be pursued.ReferenceMenni, et al. Vaccine Side-Effects and SARS-CoV-2 Infection after Vaccination in Users of the COVID Symptom Study App in the UK: A Prospective Observational Study. The Lancet Infectious Diseases 2021Apr 27. https://doi.org/10.1016/S1473-3099(21)00224-3]]></description><subject>COVID-19 vaccines</subject><subject>Immunization</subject><subject>Medical personnel</subject><subject>Pain</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>The wider impact of the pandemic</subject><issn>0040-6376</issn><issn>1468-3296</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpNkM1KAzEUhYMoWH_eIaDb0XuTaSZZav0FoYLV7ZBkbuzUOtVkWl268UV9EiMVdHUX9-Ocw8fYIcIRolTH_XQR7XshQGBxOrmzLvXR-j4dCTQbbICl0oUURm2yAUAJhZKV2mY7Kc0AQCNWA7a6RYSvj8-TlCiltnvko_HD9RlfWe_bjnikue2p4altqKAQKMfzl7gI7Zy47fJj6RK9LqnreeptCJn0T13O4m4ZG-p42_Ep2Xk_9TYSf1vEJ4ppj20FO0-0_3t32f3F-WR0VdyML69HJzeFQ4mmQNeYUqnG2hLBBy9AB0GV1Q6HTjWh0hKMg7Ih8CWUQgKCHAqrtKga7Y3cZQfr3Dw5j0x9PVssY5crazE0pRkaCTpTek2559kfgFD_WK7Xlusfy_V_y3W2LL8BsfV3_Q</recordid><startdate>20211108</startdate><enddate>20211108</enddate><creator>Muthusami, R</creator><creator>Adeyeye, S</creator><creator>Mwale, B</creator><creator>Rhammaz, S</creator><creator>Du Rand, M</creator><creator>Johnson, A</creator><creator>Du Rand, I</creator><general>BMJ Publishing Group Ltd and British Thoracic Society</general><general>BMJ Publishing Group LTD</general><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20211108</creationdate><title>P110 Assessing COVID vaccine related side-effects profile and subsequent staff sickness burden in healthcare workers</title><author>Muthusami, R ; Adeyeye, S ; Mwale, B ; Rhammaz, S ; Du Rand, M ; Johnson, A ; Du Rand, I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b1319-1bd9466daa410cfc208f2e7a8b15b6df78309b04de0c40423010352a6827d8c93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>COVID-19 vaccines</topic><topic>Immunization</topic><topic>Medical personnel</topic><topic>Pain</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>The wider impact of the pandemic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Muthusami, R</creatorcontrib><creatorcontrib>Adeyeye, S</creatorcontrib><creatorcontrib>Mwale, B</creatorcontrib><creatorcontrib>Rhammaz, S</creatorcontrib><creatorcontrib>Du Rand, M</creatorcontrib><creatorcontrib>Johnson, A</creatorcontrib><creatorcontrib>Du Rand, I</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Thorax</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Muthusami, R</au><au>Adeyeye, S</au><au>Mwale, B</au><au>Rhammaz, S</au><au>Du Rand, M</au><au>Johnson, A</au><au>Du Rand, I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>P110 Assessing COVID vaccine related side-effects profile and subsequent staff sickness burden in healthcare workers</atitle><jtitle>Thorax</jtitle><stitle>Thorax</stitle><date>2021-11-08</date><risdate>2021</risdate><volume>76</volume><issue>Suppl 2</issue><spage>A126</spage><epage>A127</epage><pages>A126-A127</pages><issn>0040-6376</issn><eissn>1468-3296</eissn><abstract><![CDATA[IntroductionThe COVID19 national immunisation campaign is well underway across the United Kingdom. A large study reported, side-effects from COVID vaccines are moderately frequent, commonly mild and short-lived in a community setting.1 ObjectivesTo examine the side-effects and staff sickness profile from COVID vaccination in healthcare workers and whether the second COVID vaccine dose (VAX2) led to worsening side-effects or sickness burden, compared to the first dose (VAX1).MethodsSelf-reported questionnaire survey to 1500 consecutive healthcare workers (working for 1 NHS Trust) receiving VAX2 at a single central vaccination site from 29/03/2021 to 23/04/2021. VAX1 data was collected at the appointment and VAX2 data asked to be returned via internal mail 7 days later. Responders were asked to grade symptoms (asymptomatic, mild, moderate or severe) & step scores of 0, 1, 2 & 3 allocated correspondingly to estimate side-effect severity changes following VAX2. Data for baseline demographics & sickness burden collected.ResultsThe response rate for VAX1 was 81% (1213) & VAX2 was 31% (464). Matched data was available for 30% (444). There was 81% female preponderance. Median age was 51 (Range 19–74, IQR 18). Most commonly reported side-effect was injection site pain (83%) followed by fatigue (46%), muscle pain (45%), headache (41%), injection site swelling (32%), injection site redness (27%), joint pain (26%), chills (21%) & fever (17%). The frequency of side-effects was similar with no significant severity change after VAX2. Mean duration of side-effects was alike (2.2 days). 3.6% and 5.6% of responders took time (mean) off work for 3.6 and 1.4 days following VAX1 & VAX2 respectively.Abstract P110 Figure 1ConclusionsOur study demonstrated healthcare workers had moderately frequent side-effects, with no significant exacerbation after VAX2. The side-effects burden was short-lived with minimal impact on workforce during resource constrained times, which suggests future booster doses in healthcare workers should remain safe and can be pursued.ReferenceMenni, et al. Vaccine Side-Effects and SARS-CoV-2 Infection after Vaccination in Users of the COVID Symptom Study App in the UK: A Prospective Observational Study. The Lancet Infectious Diseases 2021Apr 27. https://doi.org/10.1016/S1473-3099(21)00224-3]]></abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Thoracic Society</pub><doi>10.1136/thorax-2021-BTSabstracts.219</doi><oa>free_for_read</oa></addata></record> |
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| subjects | COVID-19 vaccines Immunization Medical personnel Pain Severe acute respiratory syndrome coronavirus 2 The wider impact of the pandemic |
| title | P110 Assessing COVID vaccine related side-effects profile and subsequent staff sickness burden in healthcare workers |
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