A genome‐wide association study identifies novel gene associations with facial skin wrinkling and mole count in Latin Americans

Summary Background Genome‐wide association studies (GWASs) have identified genes influencing skin ageing and mole count in Europeans, but little is known about the relevance of these (or other genes) in non‐Europeans. Objectives To conduct a GWAS for facial skin ageing and mole count in adults

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Bibliographische Detailangaben
Veröffentlicht in:	British journal of dermatology (1951) 2021-11, Vol.185 (5), p.988-998
Hauptverfasser:	Chen, Y., André, M., Adhikari, K., Blin, M., Bonfante, B., Mendoza‐Revilla, J., Fuentes‐Guajardo, M., Palmal, S., Chacón‐Duque, J.C., Hurtado, M., Villegas, V., Granja, V., Jaramillo, C., Arias, W., Lozano, R.B., Everardo‐Martínez, P., Gómez‐Valdés, J., Villamil‐Ramírez, H., Cerqueira, C.C.S., Hünemeier, T., Ramallo, V., Gonzalez‐José, R., Schüler‐Faccini, L., Bortolini, M.‐C., Acuña‐Alonzo, V., Canizales‐Quinteros, S., Gallo, C., Poletti, G., Bedoya, G., Rothhammer, F., Balding, D., Tobin, D.J., Wang, S., Faux, P., Ruiz‐Linares, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Chromosome 21 Genes Genetic analysis Genome-wide association studies Genomes Interferon regulatory factor 4 Melanoma Minority & ethnic groups Quality control Single-nucleotide polymorphism Skin
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Beschreibung
Zusammenfassung:	Summary Background Genome‐wide association studies (GWASs) have identified genes influencing skin ageing and mole count in Europeans, but little is known about the relevance of these (or other genes) in non‐Europeans. Objectives To conduct a GWAS for facial skin ageing and mole count in adults
ISSN:	0007-0963 1365-2133
DOI:	10.1111/bjd.20436