Silencing long noncoding RNA colon cancer-associated transcript-1 upregulates microRNA-34a-5p to promote proliferation and differentiation of osteoblasts in osteoporosis

Long noncoding RNAs (lncRNAs) have been revealed to be related to multiple physiological and pathology processes such as development, carcinogenesis, and osteogenesis. It is reported that lncRNAs might exert function in osteoblast differentiation and bone formation. Here, we determined this study to...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer gene therapy 2021-11, Vol.28 (10-11), p.1150-1161
Hauptverfasser:	Hu, Fangke, Jiang, Chengying, Bu, Guoyun, Fu, Yiru, Yu, Yanfang
Format:	Artikel
Sprache:	eng
Schlagworte:	13/31 13/51 38/109 631/208/199 631/80 Animals Apoptosis Biomedical and Life Sciences Biomedicine Bone growth Carcinogenesis Cell Differentiation Cell Proliferation Colon cancer Colorectal cancer Development and progression Disease Models, Animal Disease Progression Female Gene Expression Gene Therapy Genetic aspects Health aspects Humans Mineralization miRNA Non-coding RNA Osteoblastogenesis Osteoblasts Osteoblasts - metabolism Osteogenesis Osteoporosis Osteoporosis - genetics Osteoporosis - pathology Ovariectomy Pathology Physiological aspects Rats Rats, Sprague-Dawley RNA RNA, Long Noncoding - metabolism RNA-mediated interference siRNA Transcription Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!