Physiological impact of the environment on the welfare of transgenic goats raised in a tropical climate
The present study evaluated the general welfare state of two strains of transgenic goats bred in a region with a hot and humid tropical climate. Nine females were used, being three transgenic for human lysozyme (hLZ group), three transgenic for human glucocerebrosidase (hGCase group), and three non-...
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| Veröffentlicht in: | International journal of biometeorology 2021-12, Vol.65 (12), p.2147-2155 |
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| creator | Alves, Matheus Soares de Assis Dantas, Raul Andrei de Oliveira Cruz, Rosane Pereira, Vinícius Carvalho de Souza Filho, Marcos Alves da Silva, Isaac Neto Goes Neto, Saul Gaudêncio Tavares, Kaio Cesar Simiano Martins, Leonardo Tondello de Araújo, Airton Alencar |
| description | The present study evaluated the general welfare state of two strains of transgenic goats bred in a region with a hot and humid tropical climate. Nine females were used, being three transgenic for human lysozyme (hLZ group), three transgenic for human glucocerebrosidase (hGCase group), and three non-transgenic (control group). The temperature and humidity index (THI) were recorded during the morning, afternoon, and evening. The physiological parameters measured were respiratory rate, heart rate, and rectal and vaginal temperatures. Venous blood samples were collected using Vacutainer® tubes containing 10% ethylenediaminetetraacetic acid (EDTA). Also, analysis of erythrogram, leukogram, and some biochemical parameters of serum was performed. It was observed that the afternoon shift presented the largest THI, being potentially more impactful on the physiology of animals. In general, respiratory and heart rates were higher in transgenic animals, especially in the hLZ group compared to the control group (
P
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| doi_str_mv | 10.1007/s00484-021-02177-y |
| format | Article |
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P
< 0.05). Regarding the hematological parameters, the quantification of red blood cells, hemoglobin, and hematocrit was significantly lower (
P
< 0.05) in the hGCase group compared to that in the hLZ and control. The leukocyte count was considerably lower (
P
< 0.05) in the hLZ group compared to that in the hGCase and control. Correlation analysis showed that the increase in THI was associated with a change in physiological parameters normally used as indicators of thermal stress. Despite the differences found among the experimental groups, all the physiological parameters remained within the normal limits recommended for the goat species. Further studies involving a larger number of animals from different categories should be carried out to elucidate the impacts that transgenesis can have on animal welfare under different THI conditions.</description><identifier>ISSN: 0020-7128</identifier><identifier>EISSN: 1432-1254</identifier><identifier>DOI: 10.1007/s00484-021-02177-y</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Acetic acid ; Animal Physiology ; Animal welfare ; Animals ; Biological and Medical Physics ; Biophysics ; Climate ; Correlation analysis ; Earth and Environmental Science ; Environment ; Environmental Health ; Environmental impact ; Erythrocytes ; Ethylenediaminetetraacetic acids ; Glucosylceramidase ; Goats ; Heart rate ; Hematocrit ; Hemoglobin ; Humid climates ; Humidity indexes ; Leukocytes ; Lysozyme ; Meteorology ; Original Paper ; Parameters ; Physiology ; Plant Physiology ; Respiration ; Respiratory rate ; Thermal stress ; Transgenic animals ; Tropical climates ; Tubes</subject><ispartof>International journal of biometeorology, 2021-12, Vol.65 (12), p.2147-2155</ispartof><rights>ISB 2021</rights><rights>ISB 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c352t-8659354895c94b55eeefabcde2376b72f959a67d2fca7245096fb2e111de50fe3</citedby><cites>FETCH-LOGICAL-c352t-8659354895c94b55eeefabcde2376b72f959a67d2fca7245096fb2e111de50fe3</cites><orcidid>0000-0003-3445-3799</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00484-021-02177-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00484-021-02177-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Alves, Matheus Soares</creatorcontrib><creatorcontrib>de Assis Dantas, Raul Andrei</creatorcontrib><creatorcontrib>de Oliveira Cruz, Rosane</creatorcontrib><creatorcontrib>Pereira, Vinícius Carvalho</creatorcontrib><creatorcontrib>de Souza Filho, Marcos Alves</creatorcontrib><creatorcontrib>da Silva, Isaac Neto Goes</creatorcontrib><creatorcontrib>Neto, Saul Gaudêncio</creatorcontrib><creatorcontrib>Tavares, Kaio Cesar Simiano</creatorcontrib><creatorcontrib>Martins, Leonardo Tondello</creatorcontrib><creatorcontrib>de Araújo, Airton Alencar</creatorcontrib><title>Physiological impact of the environment on the welfare of transgenic goats raised in a tropical climate</title><title>International journal of biometeorology</title><addtitle>Int J Biometeorol</addtitle><description>The present study evaluated the general welfare state of two strains of transgenic goats bred in a region with a hot and humid tropical climate. Nine females were used, being three transgenic for human lysozyme (hLZ group), three transgenic for human glucocerebrosidase (hGCase group), and three non-transgenic (control group). The temperature and humidity index (THI) were recorded during the morning, afternoon, and evening. The physiological parameters measured were respiratory rate, heart rate, and rectal and vaginal temperatures. Venous blood samples were collected using Vacutainer® tubes containing 10% ethylenediaminetetraacetic acid (EDTA). Also, analysis of erythrogram, leukogram, and some biochemical parameters of serum was performed. It was observed that the afternoon shift presented the largest THI, being potentially more impactful on the physiology of animals. In general, respiratory and heart rates were higher in transgenic animals, especially in the hLZ group compared to the control group (
P
< 0.05). Regarding the hematological parameters, the quantification of red blood cells, hemoglobin, and hematocrit was significantly lower (
P
< 0.05) in the hGCase group compared to that in the hLZ and control. The leukocyte count was considerably lower (
P
< 0.05) in the hLZ group compared to that in the hGCase and control. Correlation analysis showed that the increase in THI was associated with a change in physiological parameters normally used as indicators of thermal stress. Despite the differences found among the experimental groups, all the physiological parameters remained within the normal limits recommended for the goat species. Further studies involving a larger number of animals from different categories should be carried out to elucidate the impacts that transgenesis can have on animal welfare under different THI conditions.</description><subject>Acetic acid</subject><subject>Animal Physiology</subject><subject>Animal welfare</subject><subject>Animals</subject><subject>Biological and Medical Physics</subject><subject>Biophysics</subject><subject>Climate</subject><subject>Correlation analysis</subject><subject>Earth and Environmental Science</subject><subject>Environment</subject><subject>Environmental Health</subject><subject>Environmental impact</subject><subject>Erythrocytes</subject><subject>Ethylenediaminetetraacetic acids</subject><subject>Glucosylceramidase</subject><subject>Goats</subject><subject>Heart rate</subject><subject>Hematocrit</subject><subject>Hemoglobin</subject><subject>Humid climates</subject><subject>Humidity indexes</subject><subject>Leukocytes</subject><subject>Lysozyme</subject><subject>Meteorology</subject><subject>Original Paper</subject><subject>Parameters</subject><subject>Physiology</subject><subject>Plant Physiology</subject><subject>Respiration</subject><subject>Respiratory rate</subject><subject>Thermal stress</subject><subject>Transgenic animals</subject><subject>Tropical 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B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QH</scope><scope>7TG</scope><scope>7UA</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88F</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KL.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M1Q</scope><scope>M2P</scope><scope>M7P</scope><scope>PATMY</scope><scope>PCBAR</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><orcidid>https://orcid.org/0000-0003-3445-3799</orcidid></search><sort><creationdate>20211201</creationdate><title>Physiological impact of the environment on the welfare of transgenic goats raised in a tropical climate</title><author>Alves, Matheus Soares ; de Assis Dantas, Raul Andrei ; de Oliveira Cruz, Rosane ; Pereira, Vinícius Carvalho ; de Souza Filho, Marcos Alves ; da Silva, Isaac Neto Goes ; Neto, Saul Gaudêncio ; Tavares, Kaio Cesar Simiano ; Martins, Leonardo Tondello ; de Araújo, Airton Alencar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c352t-8659354895c94b55eeefabcde2376b72f959a67d2fca7245096fb2e111de50fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Acetic acid</topic><topic>Animal Physiology</topic><topic>Animal welfare</topic><topic>Animals</topic><topic>Biological and Medical Physics</topic><topic>Biophysics</topic><topic>Climate</topic><topic>Correlation analysis</topic><topic>Earth and Environmental Science</topic><topic>Environment</topic><topic>Environmental Health</topic><topic>Environmental impact</topic><topic>Erythrocytes</topic><topic>Ethylenediaminetetraacetic acids</topic><topic>Glucosylceramidase</topic><topic>Goats</topic><topic>Heart rate</topic><topic>Hematocrit</topic><topic>Hemoglobin</topic><topic>Humid climates</topic><topic>Humidity indexes</topic><topic>Leukocytes</topic><topic>Lysozyme</topic><topic>Meteorology</topic><topic>Original Paper</topic><topic>Parameters</topic><topic>Physiology</topic><topic>Plant Physiology</topic><topic>Respiration</topic><topic>Respiratory rate</topic><topic>Thermal stress</topic><topic>Transgenic animals</topic><topic>Tropical climates</topic><topic>Tubes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alves, Matheus Soares</creatorcontrib><creatorcontrib>de Assis Dantas, Raul Andrei</creatorcontrib><creatorcontrib>de Oliveira Cruz, Rosane</creatorcontrib><creatorcontrib>Pereira, Vinícius Carvalho</creatorcontrib><creatorcontrib>de Souza Filho, 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biometeorology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alves, Matheus Soares</au><au>de Assis Dantas, Raul Andrei</au><au>de Oliveira Cruz, Rosane</au><au>Pereira, Vinícius Carvalho</au><au>de Souza Filho, Marcos Alves</au><au>da Silva, Isaac Neto Goes</au><au>Neto, Saul Gaudêncio</au><au>Tavares, Kaio Cesar Simiano</au><au>Martins, Leonardo Tondello</au><au>de Araújo, Airton Alencar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Physiological impact of the environment on the welfare of transgenic goats raised in a tropical climate</atitle><jtitle>International journal of biometeorology</jtitle><stitle>Int J Biometeorol</stitle><date>2021-12-01</date><risdate>2021</risdate><volume>65</volume><issue>12</issue><spage>2147</spage><epage>2155</epage><pages>2147-2155</pages><issn>0020-7128</issn><eissn>1432-1254</eissn><abstract>The present study evaluated the general welfare state of two strains of transgenic goats bred in a region with a hot and humid tropical climate. Nine females were used, being three transgenic for human lysozyme (hLZ group), three transgenic for human glucocerebrosidase (hGCase group), and three non-transgenic (control group). The temperature and humidity index (THI) were recorded during the morning, afternoon, and evening. The physiological parameters measured were respiratory rate, heart rate, and rectal and vaginal temperatures. Venous blood samples were collected using Vacutainer® tubes containing 10% ethylenediaminetetraacetic acid (EDTA). Also, analysis of erythrogram, leukogram, and some biochemical parameters of serum was performed. It was observed that the afternoon shift presented the largest THI, being potentially more impactful on the physiology of animals. In general, respiratory and heart rates were higher in transgenic animals, especially in the hLZ group compared to the control group (
P
< 0.05). Regarding the hematological parameters, the quantification of red blood cells, hemoglobin, and hematocrit was significantly lower (
P
< 0.05) in the hGCase group compared to that in the hLZ and control. The leukocyte count was considerably lower (
P
< 0.05) in the hLZ group compared to that in the hGCase and control. Correlation analysis showed that the increase in THI was associated with a change in physiological parameters normally used as indicators of thermal stress. Despite the differences found among the experimental groups, all the physiological parameters remained within the normal limits recommended for the goat species. Further studies involving a larger number of animals from different categories should be carried out to elucidate the impacts that transgenesis can have on animal welfare under different THI conditions.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><doi>10.1007/s00484-021-02177-y</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-3445-3799</orcidid></addata></record> |
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| subjects | Acetic acid Animal Physiology Animal welfare Animals Biological and Medical Physics Biophysics Climate Correlation analysis Earth and Environmental Science Environment Environmental Health Environmental impact Erythrocytes Ethylenediaminetetraacetic acids Glucosylceramidase Goats Heart rate Hematocrit Hemoglobin Humid climates Humidity indexes Leukocytes Lysozyme Meteorology Original Paper Parameters Physiology Plant Physiology Respiration Respiratory rate Thermal stress Transgenic animals Tropical climates Tubes |
| title | Physiological impact of the environment on the welfare of transgenic goats raised in a tropical climate |
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