A computational- cum -experimental study provides some clues on the druggable binding site and design of anticancer therapeutics on ETV1 transcription factor oncoprotein

The past few years have seen many advances in the discovery of E26 transformation-specific sequence variant 1 (ETV1)-targeted anticancer compounds. Small molecular transcriptional regulation of ETV1 has successfully impeded malignant tumors. Even so, its structural and therapeutic features remain ob...

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Veröffentlicht in:	Molecular systems design & engineering 2021-11, Vol.6 (11), p.925-935
Hauptverfasser:	I.V, Ambily Nath, A, Jero Mathu, A, Jayakumaran Nair, Nair, Achuthsankar S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Binding sites Cancer Dimers Ligands Mutation Proteins Residues
Online-Zugang:	Volltext
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