Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis

A spheroid is known as a three-dimensional culture model, which better simulates the physiological conditions of stem cells. This study is aimed at identifying genes specifically expressed in spheroid-cultured human periodontal ligament mesenchymal stem cells (hPDLMSCs) using RNA-seq analysis to eva...

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Veröffentlicht in:	Stem cells international 2021-10, Vol.2021, p.1-18
Hauptverfasser:	Suga, Takenori, Usui, Michihiko, Onizuka, Satoru, Sano, Kotaro, Sato, Tsuyoshi, Nakazawa, Kohji, Ariyoshi, Wataru, Nishihara, Tatsuji, Nakashima, Keisuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipogenesis Alkaline phosphatase Biomedical materials Cell adhesion Cell culture Cell proliferation Chondrogenesis Collagen Culture Deacetylation Differentiation (biology) Gene expression Genes Genetic aspects Genetic transcription Genomes Histones Mesenchymal stem cells Monolayers Nodules Osteogenesis Osteopontin Penicillin Periodontal ligament Physiological aspects Polyethylene glycol Polymerase chain reaction Proteins RNA Scientific equipment and supplies industry siRNA Spheroids Stem cells Teeth Three dimensional models Transcriptomes Western blotting
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