RNA-based gene targeting therapies for human papillomavirus driven cancers

While platinum-based chemotherapy, radiation therapy and or surgery are effective in reducing human papillomavirus (HPV) driven cancer tumours, they have some significant drawbacks, including low specificity for tumour, toxicity, and severe adverse effects. Though current therapies for HPV-driven ca...

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Veröffentlicht in:	Cancer letters 2021-12, Vol.523, p.111-120
Hauptverfasser:	Salinas-Montalvo, Ana María, Supramaniam, Aroon, McMillan, Nigel AJ, Idris, Adi
Format:	Artikel
Sprache:	eng
Schlagworte:	Alphapapillomavirus - genetics Apoptosis Cancer therapies Cell cycle Chemotherapy Clustered Regularly Interspaced Short Palindromic Repeats CRISPR Female Gene Editing Gene expression Gene targeting Gene Targeting - methods Gene therapy Genetic Therapy - methods Genomes Head & neck cancer HPV Human papillomavirus Humans Immune system lncRNA Medical prognosis MicroRNAs - physiology miRNA mRNA mRNA Vaccines - immunology Nanoparticles Papillomavirus Infections - therapy Papillomavirus Vaccines - immunology Proteins Quality of life Radiation therapy RNA, Long Noncoding - physiology RNA, Small Interfering - therapeutic use siRNA Toxicity Tumors Uterine Cervical Neoplasms - therapy Vaccines, Synthetic - immunology
Online-Zugang:	Volltext
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