A Novel Amperometric Aptamer-Antibody Sandwich Assay for the Detection of Tuberculosis With Diazonium Electrografted Enhanced Modified Electrode

In this study, a sensitive aptamer-antibody-based sandwich biosensor utilizing chronoamperometry for early detection of Mycobacterium tuberculosis CFP10 antigen is reported. An anti-CFP10 aminated aptamer was covalently immobilized onto the disposable screen-printed carbon electrode via carbodiimide...

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Veröffentlicht in:	IEEE sensors journal 2021-10, Vol.21 (20), p.22442-22449
Hauptverfasser:	Yunus, Muhammad Hafiznur, Yusof, Nor Azah, Raston, Nurul Hanun Ahmad, Noor, Siti Suraiya Md, Sulaiman, Yusran, Abdullah, Jaafar
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Aptamer Biosensors Buffer solutions Buffers (chemistry) Carbon CFP10 chronoamperometry diazonium salts Electrical measurement electrochemical biosensor Electrodes Electron transfer Hydrogen peroxide Hydroquinone Peroxidase Proteins Reagents Sensors Surface impedance Temperature measurement Tuberculosis
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