Downregulation of MTA-1, complex of CDK2-cyclin E, and NF-kB expressions as a molecular target therapy of oral Burkitt's lymphoma cells mediated by sense KIP-1 and antisense SKP-2

Aim: To examine the decreased of metastatic associated protein-1 (MTA-1), complex of cyclin-dependent kinase-2 (CDK2)-cyclin E, and nuclear factor-kappa beta (NF-kB) expression as a molecular target therapy of oral Burkitt's lymphoma (Raji) cells mediated by oligonucleotides KIP-1 sense (KIP-1...

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Veröffentlicht in:	Journal of international oral health 2021-09, Vol.13 (5), p.493-498
Hauptverfasser:	Supriatno, Irnawati, Dyah, Medawati, Ana, Entin Yuletnawati, Sartari
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitumor activity Apoptosis Boyden chamber Burkitt's lymphoma Care and treatment Caspase-3 Caspase-9 Cell growth Chemotaxis Cyclin E Cyclin E proteins Cyclin-dependent kinase 2 Cyclin-dependent kinases Gene expression Genetic aspects Growth inhibition Health aspects Kinases Kip protein Kip-1 protein Lymphoma Metastases Methods Molecular targeted therapy Mouth cancer NF-κB protein Oligonucleotides Protein kinases Transcription factors Tubulin Tumors
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