Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios
The increasing CO2-concentrations in the atmosphere promote ocean acidification. Seawater chemistry changes interact with contaminants, such as illicit drugs in the coastal zones. This work evaluates impacts of pH decrease and crack-cocaine exposure on the commercial mussel Perna perna through bioma...
Gespeichert in:
| Veröffentlicht in: | Marine pollution bulletin 2021-10, Vol.171, p.112735, Article 112735 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | 112735 |
| container_title | Marine pollution bulletin |
| container_volume | 171 |
| creator | da Silva Souza, Lorena Bonnail, Estefanía Maranho, Luciane Alves Pusceddu, Fabio Hermes Cortez, Fernando Sanzi Cesar, Augusto Ribeiro, Daniel Araki Riba, Inmaculada de Souza Abessa, Denis M. DelValls, Ángel Pereira, Camilo Dias Seabra |
| description | The increasing CO2-concentrations in the atmosphere promote ocean acidification. Seawater chemistry changes interact with contaminants, such as illicit drugs in the coastal zones. This work evaluates impacts of pH decrease and crack-cocaine exposure on the commercial mussel Perna perna through biomarker responses (lysosomal membrane stability, lipid peroxidation, and DNA strand breaks). The organisms were exposed to different crack-cocaine concentrations (0.5, 5.0, and 50 μg L−1) combined with different pH values (8.3, 8.0, 7.5, 7.0, 6.5, and 6.0) for 96 h. Crack-cocaine in the different acidification scenarios triggered cyto-genotoxicity, which affected the overall health of mussels exposed to cocaine environmentally relevant concentration. This study produced the first data on biomarker responses associated with CO2-induced acidification and illicit drugs (crack-cocaine) in marine organisms.
[Display omitted]
•Ocean acidification scenarios were assessed with mussel in presence of crack-cocaine.•Lysosomal membrane stability, lipid peroxidation, and DNA strand breaks in Perna perna revealed toxicity increase.•Adverse effects of acidification were detected for pH below 6.5.•At pH 7.5–6.5 adverse effects are related to combined stressors (CO2 and cocaine) |
| doi_str_mv | 10.1016/j.marpolbul.2021.112735 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2582853522</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0025326X21007694</els_id><sourcerecordid>2582853522</sourcerecordid><originalsourceid>FETCH-LOGICAL-c376t-56c62960c2088aed4919f415ea4e580a59795f93c9ba55408d10bf5a3e730c6b3</originalsourceid><addsrcrecordid>eNqFkc1uFDEQhC0EEkvCM9AS51n8s54fbqsVEKRIOSSRcrM8PT2slxl7sD2IvAZPjFeLuHLqy1dV6irG3gm-FVzUH07b2cYlTP06bSWXYiuEbJR-wTaibbpKqVq9ZBvOpa6UrJ9eszcpnTjnjWzEhv2-X_tqony0E2CYe-dpABpHwpwgjOCmyaHLMMT1G1g_wEAYyaZCLTcQPJTwooF5TYmm9BH2kI4h5iq7mYB-LSGtkSAHwGjxe8lAe-adh8OdBPLR4XEmnyEh-eIV0jV7Ndop0du_94o9fv70cLipbu--fD3sbytUTZ0rXWMtu5qj5G1radh1oht3QpPdkW651V3T6bFT2PVW6x1vB8H7UVtFjeJY9-qKvb_4LjH8WCllcwpr9CXSSN3KVistZaGaC4UxpBRpNEt05elnI7g5D2BO5t8A5jyAuQxQlPuLsvRCPx1Fk9CRRxpcLPWaIbj_evwBP8iUcQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2582853522</pqid></control><display><type>article</type><title>Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios</title><source>Elsevier ScienceDirect Journals Complete - AutoHoldings</source><creator>da Silva Souza, Lorena ; Bonnail, Estefanía ; Maranho, Luciane Alves ; Pusceddu, Fabio Hermes ; Cortez, Fernando Sanzi ; Cesar, Augusto ; Ribeiro, Daniel Araki ; Riba, Inmaculada ; de Souza Abessa, Denis M. ; DelValls, Ángel ; Pereira, Camilo Dias Seabra</creator><creatorcontrib>da Silva Souza, Lorena ; Bonnail, Estefanía ; Maranho, Luciane Alves ; Pusceddu, Fabio Hermes ; Cortez, Fernando Sanzi ; Cesar, Augusto ; Ribeiro, Daniel Araki ; Riba, Inmaculada ; de Souza Abessa, Denis M. ; DelValls, Ángel ; Pereira, Camilo Dias Seabra</creatorcontrib><description>The increasing CO2-concentrations in the atmosphere promote ocean acidification. Seawater chemistry changes interact with contaminants, such as illicit drugs in the coastal zones. This work evaluates impacts of pH decrease and crack-cocaine exposure on the commercial mussel Perna perna through biomarker responses (lysosomal membrane stability, lipid peroxidation, and DNA strand breaks). The organisms were exposed to different crack-cocaine concentrations (0.5, 5.0, and 50 μg L−1) combined with different pH values (8.3, 8.0, 7.5, 7.0, 6.5, and 6.0) for 96 h. Crack-cocaine in the different acidification scenarios triggered cyto-genotoxicity, which affected the overall health of mussels exposed to cocaine environmentally relevant concentration. This study produced the first data on biomarker responses associated with CO2-induced acidification and illicit drugs (crack-cocaine) in marine organisms.
[Display omitted]
•Ocean acidification scenarios were assessed with mussel in presence of crack-cocaine.•Lysosomal membrane stability, lipid peroxidation, and DNA strand breaks in Perna perna revealed toxicity increase.•Adverse effects of acidification were detected for pH below 6.5.•At pH 7.5–6.5 adverse effects are related to combined stressors (CO2 and cocaine)</description><identifier>ISSN: 0025-326X</identifier><identifier>EISSN: 1879-3363</identifier><identifier>DOI: 10.1016/j.marpolbul.2021.112735</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Acidification ; Biomarkers ; Carbon dioxide ; CO2 enrichment ; Coastal zone ; Coastal zones ; Cocaine ; Contaminants ; Crack cocaine ; DNA damage ; Drug abuse ; Drugs ; Exposure ; Genotoxicity ; Lipid peroxidation ; Lipids ; Marine molluscs ; Marine mussel ; Marine organisms ; Mollusks ; Mussels ; Narcotics ; Ocean acidification ; Peroxidation ; pH effects ; Seawater ; Stability</subject><ispartof>Marine pollution bulletin, 2021-10, Vol.171, p.112735, Article 112735</ispartof><rights>2021 Elsevier Ltd</rights><rights>Copyright Elsevier BV Oct 2021</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c376t-56c62960c2088aed4919f415ea4e580a59795f93c9ba55408d10bf5a3e730c6b3</citedby><cites>FETCH-LOGICAL-c376t-56c62960c2088aed4919f415ea4e580a59795f93c9ba55408d10bf5a3e730c6b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.marpolbul.2021.112735$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27922,27923,45993</link.rule.ids></links><search><creatorcontrib>da Silva Souza, Lorena</creatorcontrib><creatorcontrib>Bonnail, Estefanía</creatorcontrib><creatorcontrib>Maranho, Luciane Alves</creatorcontrib><creatorcontrib>Pusceddu, Fabio Hermes</creatorcontrib><creatorcontrib>Cortez, Fernando Sanzi</creatorcontrib><creatorcontrib>Cesar, Augusto</creatorcontrib><creatorcontrib>Ribeiro, Daniel Araki</creatorcontrib><creatorcontrib>Riba, Inmaculada</creatorcontrib><creatorcontrib>de Souza Abessa, Denis M.</creatorcontrib><creatorcontrib>DelValls, Ángel</creatorcontrib><creatorcontrib>Pereira, Camilo Dias Seabra</creatorcontrib><title>Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios</title><title>Marine pollution bulletin</title><description>The increasing CO2-concentrations in the atmosphere promote ocean acidification. Seawater chemistry changes interact with contaminants, such as illicit drugs in the coastal zones. This work evaluates impacts of pH decrease and crack-cocaine exposure on the commercial mussel Perna perna through biomarker responses (lysosomal membrane stability, lipid peroxidation, and DNA strand breaks). The organisms were exposed to different crack-cocaine concentrations (0.5, 5.0, and 50 μg L−1) combined with different pH values (8.3, 8.0, 7.5, 7.0, 6.5, and 6.0) for 96 h. Crack-cocaine in the different acidification scenarios triggered cyto-genotoxicity, which affected the overall health of mussels exposed to cocaine environmentally relevant concentration. This study produced the first data on biomarker responses associated with CO2-induced acidification and illicit drugs (crack-cocaine) in marine organisms.
[Display omitted]
•Ocean acidification scenarios were assessed with mussel in presence of crack-cocaine.•Lysosomal membrane stability, lipid peroxidation, and DNA strand breaks in Perna perna revealed toxicity increase.•Adverse effects of acidification were detected for pH below 6.5.•At pH 7.5–6.5 adverse effects are related to combined stressors (CO2 and cocaine)</description><subject>Acidification</subject><subject>Biomarkers</subject><subject>Carbon dioxide</subject><subject>CO2 enrichment</subject><subject>Coastal zone</subject><subject>Coastal zones</subject><subject>Cocaine</subject><subject>Contaminants</subject><subject>Crack cocaine</subject><subject>DNA damage</subject><subject>Drug abuse</subject><subject>Drugs</subject><subject>Exposure</subject><subject>Genotoxicity</subject><subject>Lipid peroxidation</subject><subject>Lipids</subject><subject>Marine molluscs</subject><subject>Marine mussel</subject><subject>Marine organisms</subject><subject>Mollusks</subject><subject>Mussels</subject><subject>Narcotics</subject><subject>Ocean acidification</subject><subject>Peroxidation</subject><subject>pH effects</subject><subject>Seawater</subject><subject>Stability</subject><issn>0025-326X</issn><issn>1879-3363</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNqFkc1uFDEQhC0EEkvCM9AS51n8s54fbqsVEKRIOSSRcrM8PT2slxl7sD2IvAZPjFeLuHLqy1dV6irG3gm-FVzUH07b2cYlTP06bSWXYiuEbJR-wTaibbpKqVq9ZBvOpa6UrJ9eszcpnTjnjWzEhv2-X_tqony0E2CYe-dpABpHwpwgjOCmyaHLMMT1G1g_wEAYyaZCLTcQPJTwooF5TYmm9BH2kI4h5iq7mYB-LSGtkSAHwGjxe8lAe-adh8OdBPLR4XEmnyEh-eIV0jV7Ndop0du_94o9fv70cLipbu--fD3sbytUTZ0rXWMtu5qj5G1radh1oht3QpPdkW651V3T6bFT2PVW6x1vB8H7UVtFjeJY9-qKvb_4LjH8WCllcwpr9CXSSN3KVistZaGaC4UxpBRpNEt05elnI7g5D2BO5t8A5jyAuQxQlPuLsvRCPx1Fk9CRRxpcLPWaIbj_evwBP8iUcQ</recordid><startdate>202110</startdate><enddate>202110</enddate><creator>da Silva Souza, Lorena</creator><creator>Bonnail, Estefanía</creator><creator>Maranho, Luciane Alves</creator><creator>Pusceddu, Fabio Hermes</creator><creator>Cortez, Fernando Sanzi</creator><creator>Cesar, Augusto</creator><creator>Ribeiro, Daniel Araki</creator><creator>Riba, Inmaculada</creator><creator>de Souza Abessa, Denis M.</creator><creator>DelValls, Ángel</creator><creator>Pereira, Camilo Dias Seabra</creator><general>Elsevier Ltd</general><general>Elsevier BV</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>7T7</scope><scope>7TN</scope><scope>7TV</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>F1W</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope><scope>SOI</scope></search><sort><creationdate>202110</creationdate><title>Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios</title><author>da Silva Souza, Lorena ; Bonnail, Estefanía ; Maranho, Luciane Alves ; Pusceddu, Fabio Hermes ; Cortez, Fernando Sanzi ; Cesar, Augusto ; Ribeiro, Daniel Araki ; Riba, Inmaculada ; de Souza Abessa, Denis M. ; DelValls, Ángel ; Pereira, Camilo Dias Seabra</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c376t-56c62960c2088aed4919f415ea4e580a59795f93c9ba55408d10bf5a3e730c6b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Acidification</topic><topic>Biomarkers</topic><topic>Carbon dioxide</topic><topic>CO2 enrichment</topic><topic>Coastal zone</topic><topic>Coastal zones</topic><topic>Cocaine</topic><topic>Contaminants</topic><topic>Crack cocaine</topic><topic>DNA damage</topic><topic>Drug abuse</topic><topic>Drugs</topic><topic>Exposure</topic><topic>Genotoxicity</topic><topic>Lipid peroxidation</topic><topic>Lipids</topic><topic>Marine molluscs</topic><topic>Marine mussel</topic><topic>Marine organisms</topic><topic>Mollusks</topic><topic>Mussels</topic><topic>Narcotics</topic><topic>Ocean acidification</topic><topic>Peroxidation</topic><topic>pH effects</topic><topic>Seawater</topic><topic>Stability</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>da Silva Souza, Lorena</creatorcontrib><creatorcontrib>Bonnail, Estefanía</creatorcontrib><creatorcontrib>Maranho, Luciane Alves</creatorcontrib><creatorcontrib>Pusceddu, Fabio Hermes</creatorcontrib><creatorcontrib>Cortez, Fernando Sanzi</creatorcontrib><creatorcontrib>Cesar, Augusto</creatorcontrib><creatorcontrib>Ribeiro, Daniel Araki</creatorcontrib><creatorcontrib>Riba, Inmaculada</creatorcontrib><creatorcontrib>de Souza Abessa, Denis M.</creatorcontrib><creatorcontrib>DelValls, Ángel</creatorcontrib><creatorcontrib>Pereira, Camilo Dias Seabra</creatorcontrib><collection>CrossRef</collection><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Oceanic Abstracts</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environment Abstracts</collection><jtitle>Marine pollution bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>da Silva Souza, Lorena</au><au>Bonnail, Estefanía</au><au>Maranho, Luciane Alves</au><au>Pusceddu, Fabio Hermes</au><au>Cortez, Fernando Sanzi</au><au>Cesar, Augusto</au><au>Ribeiro, Daniel Araki</au><au>Riba, Inmaculada</au><au>de Souza Abessa, Denis M.</au><au>DelValls, Ángel</au><au>Pereira, Camilo Dias Seabra</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios</atitle><jtitle>Marine pollution bulletin</jtitle><date>2021-10</date><risdate>2021</risdate><volume>171</volume><spage>112735</spage><pages>112735-</pages><artnum>112735</artnum><issn>0025-326X</issn><eissn>1879-3363</eissn><abstract>The increasing CO2-concentrations in the atmosphere promote ocean acidification. Seawater chemistry changes interact with contaminants, such as illicit drugs in the coastal zones. This work evaluates impacts of pH decrease and crack-cocaine exposure on the commercial mussel Perna perna through biomarker responses (lysosomal membrane stability, lipid peroxidation, and DNA strand breaks). The organisms were exposed to different crack-cocaine concentrations (0.5, 5.0, and 50 μg L−1) combined with different pH values (8.3, 8.0, 7.5, 7.0, 6.5, and 6.0) for 96 h. Crack-cocaine in the different acidification scenarios triggered cyto-genotoxicity, which affected the overall health of mussels exposed to cocaine environmentally relevant concentration. This study produced the first data on biomarker responses associated with CO2-induced acidification and illicit drugs (crack-cocaine) in marine organisms.
[Display omitted]
•Ocean acidification scenarios were assessed with mussel in presence of crack-cocaine.•Lysosomal membrane stability, lipid peroxidation, and DNA strand breaks in Perna perna revealed toxicity increase.•Adverse effects of acidification were detected for pH below 6.5.•At pH 7.5–6.5 adverse effects are related to combined stressors (CO2 and cocaine)</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><doi>10.1016/j.marpolbul.2021.112735</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0025-326X |
| ispartof | Marine pollution bulletin, 2021-10, Vol.171, p.112735, Article 112735 |
| issn | 0025-326X 1879-3363 |
| language | eng |
| recordid | cdi_proquest_journals_2582853522 |
| source | Elsevier ScienceDirect Journals Complete - AutoHoldings |
| subjects | Acidification Biomarkers Carbon dioxide CO2 enrichment Coastal zone Coastal zones Cocaine Contaminants Crack cocaine DNA damage Drug abuse Drugs Exposure Genotoxicity Lipid peroxidation Lipids Marine molluscs Marine mussel Marine organisms Mollusks Mussels Narcotics Ocean acidification Peroxidation pH effects Seawater Stability |
| title | Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T17%3A13%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sub-lethal%20combined%20effects%20of%20illicit%20drug%20and%20decreased%20pH%20on%20marine%20mussels:%20A%20short-time%20exposure%20to%20crack%20cocaine%20in%20CO2%20enrichment%20scenarios&rft.jtitle=Marine%20pollution%20bulletin&rft.au=da%20Silva%20Souza,%20Lorena&rft.date=2021-10&rft.volume=171&rft.spage=112735&rft.pages=112735-&rft.artnum=112735&rft.issn=0025-326X&rft.eissn=1879-3363&rft_id=info:doi/10.1016/j.marpolbul.2021.112735&rft_dat=%3Cproquest_cross%3E2582853522%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2582853522&rft_id=info:pmid/&rft_els_id=S0025326X21007694&rfr_iscdi=true |