Diclofenac down-regulates COX-2 induced expression of CD44 and ICAM-1 in human HT29 colorectal cancer cells

Cyclooxygenase-2 (COX-2) is expressed in a variety of human colorectal cancer cells and can contribute to carcinogenesis. This study aimed to investigate the effect of diclofenac (DCF), a selective COX-2 inhibitor, on cell adhesion molecules and apoptosis in human colon adenocarcinoma cells. Levels...

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Veröffentlicht in:Naunyn-Schmiedeberg's archives of pharmacology 2021-11, Vol.394 (11), p.2259-2272
Hauptverfasser: Yilmaz, Çağatay, Köksoy, Sadi, Çeker, Tuğçe, Aslan, Mutay
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Sprache:eng
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