Natural killer cell immunosuppressive function requires CXCR3-dependent redistribution within lymphoid tissues

NK cell suppression of T cells is a key determinant of viral pathogenesis and vaccine efficacy. This process involves perforindependent elimination of activated CD4+ T cells during the first 3 days of infection. Although this mechanism requires cell-cell contact, NK cells and T cells typically resid...

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Veröffentlicht in:The Journal of clinical investigation 2021-09, Vol.131 (18), p.1-7
Hauptverfasser: Ali, Ayad, Canaday, Laura M, Feldman, H Alex, Cevik, Hilal, Moran, Michael T, Rajaram, Sanjeeth, Lakes, Nora, Tuazon, Jasmine A, Seelamneni, Harsha, Krishnamurthy, Durga, Blass, Eryn, Barouch, Dan H, Waggoner, Stephen N
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Sprache:eng
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