Transition Metal‐Free, Free‐Radical Sulfenylation of the α‐C(sp3)−H Bond in Arylacetamides and Its Application Toward 2‐Thiomethyl Benzoxazoles Synthesis

This paper reports the transition metal‐free C(sp3)−H sulfenylation of arylacetamides by using thiophenols as the sulfenyl reagents. The reactions take place in the presence of only K3PO4. Control experiments indicate that the reactions proceed via a featured sulfur‐centred free radical intermediate...

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Veröffentlicht in:	Advanced synthesis & catalysis 2021-10, Vol.363 (19), p.4627-4631
Hauptverfasser:	Tian, Shanghui, Wang, Chaoli, Xia, Jianhui, Wan, Jie‐Ping, Liu, Yunyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Arylacetamide C(sp3)−H bond Chemical reactions Free radical Free radicals Potassium phosphates Reagents Sulfenylation Synthesis Transition metal-free Transition metals
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