Simultaneous determination of ezetimibe, atorvastatin and simvastatin using quadrupole LC-MS: Application to combined tablets and plasma after SPE

A simple and sensitive liquid chromatography-mass spectrometric (LC-MS) method has been developed and validated for the simultaneous determination of ezetimibe (EZE), atorvastatin calcium (ATO), and simvastatin (SMV) in combined dosage forms and human plasma. Successful separation of the studied dru...

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Veröffentlicht in:	Acta chromatographica 2021-09, Vol.33 (3), p.245-252
Hauptverfasser:	Elawady, Tarek, Ibrahim, Fawzia, Khedr, Alaa, Belal, Fathalla
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetonitrile Atorvastatin Blood plasma Diclofenac Drugs Flow velocity Formic acid Liquid chromatography Quadrupoles Simvastatin Solid phases Spectrometry Tablets
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