Synthetic biology in various cellular and molecular fields: applications, limitations, and perspective
Synthetic biology breakthroughs have facilitated genetic circuit engineering to program cells through novel biological functions, dynamic gene expressions, as well as logic controls. SynBio can also participate in the rapid development of new treatments required for the human lifestyle. Moreover, th...
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| Veröffentlicht in: | Molecular biology reports 2020-08, Vol.47 (8), p.6207-6216 |
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| container_title | Molecular biology reports |
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| creator | Safaei, Mohsen Mobini, Gholam-Reza Abiri, Ardavan Shojaeian, Ali |
| description | Synthetic biology breakthroughs have facilitated genetic circuit engineering to program cells through novel biological functions, dynamic gene expressions, as well as logic controls. SynBio can also participate in the rapid development of new treatments required for the human lifestyle. Moreover, these technologies are applied in the development of innovative therapeutic, diagnostic, as well as discovery-related methods within a wide range of cellular and molecular applications. In the present review study, SynBio applications in various cellular and molecular fields such as novel strategies for cancer therapy, biosensing, metabolic engineering, protein engineering, and tissue engineering were highlighted and summarized. The major safety and regulatory concerns about synthetic biology will be the environmental release, legal concerns, and risks of the engineered organisms. The final sections focused on limitations to SynBio. |
| doi_str_mv | 10.1007/s11033-020-05565-6 |
| format | Article |
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| subjects | Animal Anatomy Animal Biochemistry Animals Biomedical and Life Sciences Biosensing Techniques - methods Biosensors Engineering Environmental release Gene Regulatory Networks Genetic Engineering - methods Genetic Therapy - methods Histology Humans Life Sciences Medical innovations Metabolic engineering Morphology Neoplasms - genetics Neoplasms - therapy Protein engineering Review Synthetic biology Synthetic Biology - methods Tissue engineering Tissue Engineering - methods |
| title | Synthetic biology in various cellular and molecular fields: applications, limitations, and perspective |
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