Neuroprotective effect of sesamol against aluminum nanoparticle-induced toxicity in rats

Alumina nanoparticles (ALNPs) are widely used causing neurobehavioral impairment in intoxicated animals and humans. Sesamol (SML) emerged as a natural phytochemical with potent antioxidant and anti-inflammatory properties. However, no study has directly tested the potential of SML to protect against...

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Veröffentlicht in:	Environmental science and pollution research international 2021-10, Vol.28 (38), p.53767-53780
Hauptverfasser:	Abou-Zeid, Shimaa M., Elkhadrawey, Basma A., Anis, Anis, AbuBakr, Huda O., El-Bialy, Badr E., Elsabbagh, Hesham S., El-Borai, Nermeen B.
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Hydroxydeoxyguanosine Acetylcholinesterase Aluminum Aluminum oxide Anti-inflammatory agents Antioxidants Apoptosis Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Brain Caspase-3 Cerebellum Cerebrum Degeneration Depletion DNA damage Earth and Environmental Science Ecotoxicology Edema Environment Environmental Chemistry Environmental Health Environmental science Hemorrhage IL-1β Inflammation Interleukin 6 Lipid peroxidation Lipids Medulla oblongata Nanoparticles Neurodegeneration Neuroprotection Neurotoxicity Oral administration Oxidative stress Peroxidation Phytochemicals Purkinje cells Research Article Serum levels Toxicity Tumor necrosis factor-α Waste Water Technology Water Management Water Pollution Control
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