Cost of Type 2 Diabetes Patients with Chronic Kidney Disease Based on Real-World Data: An Observational Population-Based Study in Spain
This study analyzed the prevalence, costs and economic impact of chronic kidney disease CKD in patients with T2D in a Spanish Health District using real-world data. Observational cross-sectional study in adult patients with T2D was through data extracted from the information systems of the Valencia...
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| Veröffentlicht in: | International journal of environmental research and public health 2021-09, Vol.18 (18), p.9853, Article 9853 |
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| creator | Uso-Talamantes, Ruth Gonzalez-de-Julian, Silvia Diaz-Carnicero, Javier Sauri-Ferrer, Inmaculada Luis Trillo-Mata, Jose Carrasco-Perez, Marc Navarro-Perez, Jorge Luis Gorriz, Jose Vivas-Consuelo, David Redon, Josep |
| description | This study analyzed the prevalence, costs and economic impact of chronic kidney disease CKD in patients with T2D in a Spanish Health District using real-world data. Observational cross-sectional study in adult patients with T2D was through data extracted from the information systems of the Valencia Clinico-La Malvarrosa Health District in the year 2015. Patients were stratified with the KDIGO classification for CKD. Additionally, patients were assigned to Clinical Risk Groups (CRGs) according to multimorbidity. Direct costs of primary and specialized care, and medication were estimated. The prevalence of T2D in the database population (n = 28,345) was 10.8% (mean age (SD) = 67.8 years (13.9); 51.5% male). Up to 14.935 patients (52.6%) had data on kidney function. According to the KDIGO classification, 66.2% of the patients were at low risk of CKD, 20.6% at moderately increased risk, 7.9% at high risk, and 5.2% at very high risk. The average healthcare costs associated with these four risk groups were EUR 3437, EUR 4936, EUR 5899 and EUR 7389, respectively. The large number of T2D patients with CKD in the early stages of the disease generated a significant increase in direct healthcare costs. The economic impact could be mitigated by early and comprehensive therapeutic approaches. |
| doi_str_mv | 10.3390/ijerph18189853 |
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Observational cross-sectional study in adult patients with T2D was through data extracted from the information systems of the Valencia Clinico-La Malvarrosa Health District in the year 2015. Patients were stratified with the KDIGO classification for CKD. Additionally, patients were assigned to Clinical Risk Groups (CRGs) according to multimorbidity. Direct costs of primary and specialized care, and medication were estimated. The prevalence of T2D in the database population (n = 28,345) was 10.8% (mean age (SD) = 67.8 years (13.9); 51.5% male). Up to 14.935 patients (52.6%) had data on kidney function. According to the KDIGO classification, 66.2% of the patients were at low risk of CKD, 20.6% at moderately increased risk, 7.9% at high risk, and 5.2% at very high risk. The average healthcare costs associated with these four risk groups were EUR 3437, EUR 4936, EUR 5899 and EUR 7389, respectively. The large number of T2D patients with CKD in the early stages of the disease generated a significant increase in direct healthcare costs. The economic impact could be mitigated by early and comprehensive therapeutic approaches.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph18189853</identifier><identifier>PMID: 34574782</identifier><language>eng</language><publisher>BASEL: Mdpi</publisher><subject>Age ; Cardiovascular disease ; Chronic illnesses ; Classification ; Comorbidity ; Costs ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Economic impact ; Environmental Sciences ; Environmental Sciences & Ecology ; Health care ; Hospitals ; Impact analysis ; Information systems ; Kidney diseases ; Kidneys ; Laboratories ; Life Sciences & Biomedicine ; Patients ; Peritoneal dialysis ; Pharmacy ; Population ; Population studies ; Population-based studies ; Primary care ; Public, Environmental & Occupational Health ; Risk ; Risk groups ; Science & Technology ; Transplants & implants</subject><ispartof>International journal of environmental research and public health, 2021-09, Vol.18 (18), p.9853, Article 9853</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). 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Observational cross-sectional study in adult patients with T2D was through data extracted from the information systems of the Valencia Clinico-La Malvarrosa Health District in the year 2015. Patients were stratified with the KDIGO classification for CKD. Additionally, patients were assigned to Clinical Risk Groups (CRGs) according to multimorbidity. Direct costs of primary and specialized care, and medication were estimated. The prevalence of T2D in the database population (n = 28,345) was 10.8% (mean age (SD) = 67.8 years (13.9); 51.5% male). Up to 14.935 patients (52.6%) had data on kidney function. According to the KDIGO classification, 66.2% of the patients were at low risk of CKD, 20.6% at moderately increased risk, 7.9% at high risk, and 5.2% at very high risk. The average healthcare costs associated with these four risk groups were EUR 3437, EUR 4936, EUR 5899 and EUR 7389, respectively. The large number of T2D patients with CKD in the early stages of the disease generated a significant increase in direct healthcare costs. The economic impact could be mitigated by early and comprehensive therapeutic approaches.</description><subject>Age</subject><subject>Cardiovascular disease</subject><subject>Chronic illnesses</subject><subject>Classification</subject><subject>Comorbidity</subject><subject>Costs</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Economic impact</subject><subject>Environmental Sciences</subject><subject>Environmental Sciences & Ecology</subject><subject>Health care</subject><subject>Hospitals</subject><subject>Impact analysis</subject><subject>Information systems</subject><subject>Kidney diseases</subject><subject>Kidneys</subject><subject>Laboratories</subject><subject>Life Sciences & Biomedicine</subject><subject>Patients</subject><subject>Peritoneal dialysis</subject><subject>Pharmacy</subject><subject>Population</subject><subject>Population studies</subject><subject>Population-based 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Spain</atitle><jtitle>International journal of environmental research and public health</jtitle><stitle>INT J ENV RES PUB HE</stitle><date>2021-09-18</date><risdate>2021</risdate><volume>18</volume><issue>18</issue><spage>9853</spage><pages>9853-</pages><artnum>9853</artnum><issn>1660-4601</issn><issn>1661-7827</issn><eissn>1660-4601</eissn><abstract>This study analyzed the prevalence, costs and economic impact of chronic kidney disease CKD in patients with T2D in a Spanish Health District using real-world data. 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| subjects | Age Cardiovascular disease Chronic illnesses Classification Comorbidity Costs Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Economic impact Environmental Sciences Environmental Sciences & Ecology Health care Hospitals Impact analysis Information systems Kidney diseases Kidneys Laboratories Life Sciences & Biomedicine Patients Peritoneal dialysis Pharmacy Population Population studies Population-based studies Primary care Public, Environmental & Occupational Health Risk Risk groups Science & Technology Transplants & implants |
| title | Cost of Type 2 Diabetes Patients with Chronic Kidney Disease Based on Real-World Data: An Observational Population-Based Study in Spain |
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