Oxidized low-density lipoprotein stimulates dendritic cells maturation via LOX-1-mediated MAPK/NF-kB pathway

Dendritic cells (DCs) play a crucial role as central orchestrators of immune system response in atherosclerosis initiation and progression. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is involved in the immune maturation of DCs, but the underlying mechanisms remain unclear. We is...

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Veröffentlicht in:	Brazilian journal of medical and biological research 2021-01, Vol.54 (9), p.1
Hauptverfasser:	Huang, D, Gao, W, Lu, H, Qian, J Y, Ge, J B
Format:	Artikel
Sprache:	eng
Schlagworte:	Arteriosclerosis Atherosclerosis Bone marrow CD11c antigen Colony-stimulating factor Cytokines Dendritic cells Immune system Inflammation Lipoproteins LOX-1 protein MAP kinase Maturation NF-κB protein Osteoprogenitor cells Progenitor cells Receptor density siRNA
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