Evaluation of Contamination Status and Health Risk Assessment of Essential and Toxic Metals in Cyprinus carpio from Mangla Lake, Pakistan
Although fish as a diet has many health benefits, metal accumulation in fish has been an increasing public health concerns across the world. The Cyprinus carpio samples were collected from Mangla Lake, Mirpur, Azad Kashmir, Pakistan, and analyzed for 18 essential and toxic trace metals. In edible mu...
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| Veröffentlicht in: | Biological trace element research 2021-11, Vol.199 (11), p.4284-4294 |
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| creator | Saleem, Muhammad Shi, Zongbo Shah, Munir H. |
| description | Although fish as a diet has many health benefits, metal accumulation in fish has been an increasing public health concerns across the world. The
Cyprinus carpio
samples were collected from Mangla Lake, Mirpur, Azad Kashmir, Pakistan, and analyzed for 18 essential and toxic trace metals. In edible muscles of the fish, average concentration (μg/g) of K (3002) was the highest, followed by Na (648), Ca (435), Mg (227), and Zn (161). Relatively lower levels (μg/g) were noted for Fe (16.9), Pb (6.05), Sr (4.01), Se (3.49), Co (2.90), Ni (2.37), Mn (2.29), As (1.48), and Cu (1.37), while least levels (μg/g) were found for Cr (0.61), Cd (0.52), Hg (0.15), and Li (0.09) in muscles. Majority of the metals revealed higher accumulation in gills compared with those in scales and muscles. Mean levels of Zn, Mn, Co, Pb, As, and Cd in
Cyprinus carpio
muscles were found to be exceeding most of the international permissible limits in muscles for safe human consumption. Estimated daily/weekly intakes and hazard quotients/index suggested a high risk related to the intake of
Cyprinus carpio
from Mangla Lake due to heavy metal contamination. Likewise, target cancer risk (TCR) also indicated significant lifetime carcinogenic health risks to the consumers. |
| doi_str_mv | 10.1007/s12011-020-02540-x |
| format | Article |
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Cyprinus carpio
samples were collected from Mangla Lake, Mirpur, Azad Kashmir, Pakistan, and analyzed for 18 essential and toxic trace metals. In edible muscles of the fish, average concentration (μg/g) of K (3002) was the highest, followed by Na (648), Ca (435), Mg (227), and Zn (161). Relatively lower levels (μg/g) were noted for Fe (16.9), Pb (6.05), Sr (4.01), Se (3.49), Co (2.90), Ni (2.37), Mn (2.29), As (1.48), and Cu (1.37), while least levels (μg/g) were found for Cr (0.61), Cd (0.52), Hg (0.15), and Li (0.09) in muscles. Majority of the metals revealed higher accumulation in gills compared with those in scales and muscles. Mean levels of Zn, Mn, Co, Pb, As, and Cd in
Cyprinus carpio
muscles were found to be exceeding most of the international permissible limits in muscles for safe human consumption. Estimated daily/weekly intakes and hazard quotients/index suggested a high risk related to the intake of
Cyprinus carpio
from Mangla Lake due to heavy metal contamination. Likewise, target cancer risk (TCR) also indicated significant lifetime carcinogenic health risks to the consumers.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>DOI: 10.1007/s12011-020-02540-x</identifier><identifier>PMID: 33411149</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Accumulation ; Animals ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; Cadmium ; Carcinogens ; Carps ; Chromium ; Contamination ; Copper ; Cyprinus carpio ; Environmental Monitoring ; Fish ; Freshwater fishes ; Gills ; Health risks ; Heavy metals ; Humans ; Lakes ; Lead ; Life Sciences ; Manganese ; Mercury ; Metals ; Metals, Heavy - analysis ; Metals, Heavy - toxicity ; Muscles ; Nickel ; Nutrition ; Oncology ; Original Article ; Pakistan ; Public health ; Quotients ; Risk Assessment ; Risk management ; Selenium ; Trace metals ; Water Pollutants, Chemical - analysis ; Water Pollutants, Chemical - toxicity ; Weekly ; Zinc</subject><ispartof>Biological trace element research, 2021-11, Vol.199 (11), p.4284-4294</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-8a58c0e4fecdafa9f6055e504b66098e3be0cf63c1dd7e0ec42a5e69a48d07ae3</citedby><cites>FETCH-LOGICAL-c375t-8a58c0e4fecdafa9f6055e504b66098e3be0cf63c1dd7e0ec42a5e69a48d07ae3</cites><orcidid>0000-0003-4445-4293</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12011-020-02540-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12011-020-02540-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33411149$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saleem, Muhammad</creatorcontrib><creatorcontrib>Shi, Zongbo</creatorcontrib><creatorcontrib>Shah, Munir H.</creatorcontrib><title>Evaluation of Contamination Status and Health Risk Assessment of Essential and Toxic Metals in Cyprinus carpio from Mangla Lake, Pakistan</title><title>Biological trace element research</title><addtitle>Biol Trace Elem Res</addtitle><addtitle>Biol Trace Elem Res</addtitle><description>Although fish as a diet has many health benefits, metal accumulation in fish has been an increasing public health concerns across the world. The
Cyprinus carpio
samples were collected from Mangla Lake, Mirpur, Azad Kashmir, Pakistan, and analyzed for 18 essential and toxic trace metals. In edible muscles of the fish, average concentration (μg/g) of K (3002) was the highest, followed by Na (648), Ca (435), Mg (227), and Zn (161). Relatively lower levels (μg/g) were noted for Fe (16.9), Pb (6.05), Sr (4.01), Se (3.49), Co (2.90), Ni (2.37), Mn (2.29), As (1.48), and Cu (1.37), while least levels (μg/g) were found for Cr (0.61), Cd (0.52), Hg (0.15), and Li (0.09) in muscles. Majority of the metals revealed higher accumulation in gills compared with those in scales and muscles. Mean levels of Zn, Mn, Co, Pb, As, and Cd in
Cyprinus carpio
muscles were found to be exceeding most of the international permissible limits in muscles for safe human consumption. Estimated daily/weekly intakes and hazard quotients/index suggested a high risk related to the intake of
Cyprinus carpio
from Mangla Lake due to heavy metal contamination. Likewise, target cancer risk (TCR) also indicated significant lifetime carcinogenic health risks to the consumers.</description><subject>Accumulation</subject><subject>Animals</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Cadmium</subject><subject>Carcinogens</subject><subject>Carps</subject><subject>Chromium</subject><subject>Contamination</subject><subject>Copper</subject><subject>Cyprinus carpio</subject><subject>Environmental Monitoring</subject><subject>Fish</subject><subject>Freshwater fishes</subject><subject>Gills</subject><subject>Health risks</subject><subject>Heavy metals</subject><subject>Humans</subject><subject>Lakes</subject><subject>Lead</subject><subject>Life Sciences</subject><subject>Manganese</subject><subject>Mercury</subject><subject>Metals</subject><subject>Metals, Heavy - analysis</subject><subject>Metals, Heavy - toxicity</subject><subject>Muscles</subject><subject>Nickel</subject><subject>Nutrition</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Pakistan</subject><subject>Public health</subject><subject>Quotients</subject><subject>Risk Assessment</subject><subject>Risk management</subject><subject>Selenium</subject><subject>Trace metals</subject><subject>Water Pollutants, Chemical - 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The
Cyprinus carpio
samples were collected from Mangla Lake, Mirpur, Azad Kashmir, Pakistan, and analyzed for 18 essential and toxic trace metals. In edible muscles of the fish, average concentration (μg/g) of K (3002) was the highest, followed by Na (648), Ca (435), Mg (227), and Zn (161). Relatively lower levels (μg/g) were noted for Fe (16.9), Pb (6.05), Sr (4.01), Se (3.49), Co (2.90), Ni (2.37), Mn (2.29), As (1.48), and Cu (1.37), while least levels (μg/g) were found for Cr (0.61), Cd (0.52), Hg (0.15), and Li (0.09) in muscles. Majority of the metals revealed higher accumulation in gills compared with those in scales and muscles. Mean levels of Zn, Mn, Co, Pb, As, and Cd in
Cyprinus carpio
muscles were found to be exceeding most of the international permissible limits in muscles for safe human consumption. Estimated daily/weekly intakes and hazard quotients/index suggested a high risk related to the intake of
Cyprinus carpio
from Mangla Lake due to heavy metal contamination. Likewise, target cancer risk (TCR) also indicated significant lifetime carcinogenic health risks to the consumers.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>33411149</pmid><doi>10.1007/s12011-020-02540-x</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0003-4445-4293</orcidid></addata></record> |
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| ispartof | Biological trace element research, 2021-11, Vol.199 (11), p.4284-4294 |
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| subjects | Accumulation Animals Biochemistry Biomedical and Life Sciences Biotechnology Cadmium Carcinogens Carps Chromium Contamination Copper Cyprinus carpio Environmental Monitoring Fish Freshwater fishes Gills Health risks Heavy metals Humans Lakes Lead Life Sciences Manganese Mercury Metals Metals, Heavy - analysis Metals, Heavy - toxicity Muscles Nickel Nutrition Oncology Original Article Pakistan Public health Quotients Risk Assessment Risk management Selenium Trace metals Water Pollutants, Chemical - analysis Water Pollutants, Chemical - toxicity Weekly Zinc |
| title | Evaluation of Contamination Status and Health Risk Assessment of Essential and Toxic Metals in Cyprinus carpio from Mangla Lake, Pakistan |
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