Hand-foot skin reaction with primarily dorsal involvement in a patient with metastatic renal cell carcinoma on cabozantinib

A 61-year-old man with metastatic renal cell carcinoma on cabozantinib developed hand-foot skin reaction with predominantly dorsal involvement including painful violaceous plaques over the joints and keratotic yellow plaques on the palmar fingers. The medication was discontinued with resolution of t...

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Veröffentlicht in:Dermatology online journal 2020-08, Vol.26 (8)
Hauptverfasser: Goyal, Amrita, Jacobsen, Audrey A, O'Leary, Daniel, Watson, Allison, Luikart, Sharon, Gaddis, Kevin J
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container_title Dermatology online journal
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creator Goyal, Amrita
Jacobsen, Audrey A
O'Leary, Daniel
Watson, Allison
Luikart, Sharon
Gaddis, Kevin J
description A 61-year-old man with metastatic renal cell carcinoma on cabozantinib developed hand-foot skin reaction with predominantly dorsal involvement including painful violaceous plaques over the joints and keratotic yellow plaques on the palmar fingers. The medication was discontinued with resolution of the plaques and later reinitiated at a lower dose uneventfully.
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subjects Anilides - adverse effects
Anilides - therapeutic use
Biopsy
Carcinoma, Renal Cell - drug therapy
Foot Dermatoses - chemically induced
Hand Dermatoses - chemically induced
Hand Dermatoses - pathology
Humans
Inhibitor drugs
Kidney cancer
Kidney Neoplasms - drug therapy
Male
Metastasis
Middle Aged
Protein Kinase Inhibitors - adverse effects
Protein Kinase Inhibitors - therapeutic use
Pyridines - adverse effects
Pyridines - therapeutic use
Receptor Protein-Tyrosine Kinases - antagonists & inhibitors
Skin - pathology
Targeted cancer therapy
title Hand-foot skin reaction with primarily dorsal involvement in a patient with metastatic renal cell carcinoma on cabozantinib
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