Three‐finger proteins from snakes and humans acting on nicotinic receptors: Old and new

The first toxin to give rise to the three‐finger protein (TFP) family was α‐bungarotoxin (α‐Bgt) from Bungarus multicinctus krait venom. α‐Bgt was crucial for research on nicotinic acetylcholine receptors (nAChRs), and in this Review article we focus on present data for snake venom TFPs and those of...

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Veröffentlicht in:	Journal of neurochemistry 2021-09, Vol.158 (6), p.1223-1235
Hauptverfasser:	Tsetlin, Victor I., Kasheverov, Igor E., Utkin, Yuri N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors (muscarinic) Acetylcholine receptors (nicotinic) Binding sites Bungarotoxin Dimers E coli Ly6 proteins Molecular structure nicotinic acetylcholine receptors NMR Nuclear magnetic resonance Proteins Receptors snake venom neurotoxins Snakes three‐finger proteins Toxins Venom γ-Aminobutyric acid
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