P018 Alcohol consumption post-liver transplantation at a Portuguese center: a cross-sectional study
BackgroundAlcohol-associated liver disease (ALD) is one of the leading causes of liver transplantation (LT). However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe cond...
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Veröffentlicht in: | Gut 2021-09, Vol.70 (Suppl 3), p.A17-A18 |
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creator | Rebelo, Carolina Chálim Félix, Catarina Cardoso, Filipe Bagulho, Luís Sousa, Mónica Mendes, Milena Glória, Helena Mateus, Élia Marques, Hugo Pinto Nolasco, Fernando Martins, Américo Perdigoto, Rui |
description | BackgroundAlcohol-associated liver disease (ALD) is one of the leading causes of liver transplantation (LT). However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe conducted a cross-sectional study including LT recipients transplanted in 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pre-tested survey including questions on demography, family, employment and social status, and a validated Portuguese translation of the Alcohol Use Disorder Identification Test (AUDIT) was applied via telephone call. Alcohol consumption was defined by patients’ self-report or a positive AUDIT. Informed consent was conveyed by accepting to respond the survey. No donor organs were obtained from executed prisoners or other institutionalized persons.ResultsIn 2019, 122 patients underwent LT at Curry Cabral Hospital. At interview date (June 2021), 19 recipients had died, 2 were being followed abroad, 2 did not consent and 99 answered the survey. Among responders mean±SD age was 57±10-year-old, 70 (70.7%) were males, and 49 (49.5%) underwent ALD-related LT. During a median (IQR) follow-up of 24 (20–26) months post index LT, 22 recipients (22.2%) consumed alcohol: 14 had a drink once a month or less and 8 drank 1–4 times/month. On drinking days, 18 consumed 1–2 drinks and the remainder no more than 3–4 drinks. Only one patient reported to have drunk ≥6 drinks on one occasion. All post-LT drinking recipients were considered low-risk (score |
doi_str_mv | 10.1136/gutjnl-2021-BASL.27 |
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fullrecord | <record><control><sourceid>proquest_bmj_j</sourceid><recordid>TN_cdi_proquest_journals_2573704090</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2573704090</sourcerecordid><originalsourceid>FETCH-LOGICAL-b1137-945584a5c176f5ef46ccbac30eafdd95331aba371b73c590ce2f58f90a7c1bb93</originalsourceid><addsrcrecordid>eNpFkM1KxDAURoMoOI4-gZuC6zg3SdMk7sbBPxhwQF2HNJOOUzJNbVLBnRtf1CexdQRXF-49fHz3IHRO4JIQVsw2faobjylQgq_nT8tLKg7QhOSFxIxKeYgmAERgLnJ1jE5irAFASkUmyK2AyO_Pr7m34TX4zIYm9rs2bUOTtSEm7LfvrstSZ5rYetMk83syKTPZKnSp3_Quusy6JrnualjaLsSIo7MjZ3wWU7_-OEVHlfHRnf3NKXq5vXle3OPl493DYr7E5fCGwCrnXOaGWyKKirsqL6wtjWXgTLVeK84YMaVhgpSCWa7AOlpxWSkwwpKyVGyKLva5bRfehmJJ16HvhhpRUy6YgBwUDNRsT5W7-h8goEeXeu9Sjy716FJTwX4A9_1sDg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2573704090</pqid></control><display><type>article</type><title>P018 Alcohol consumption post-liver transplantation at a Portuguese center: a cross-sectional study</title><source>PubMed Central</source><creator>Rebelo, Carolina Chálim ; Félix, Catarina ; Cardoso, Filipe ; Bagulho, Luís ; Sousa, Mónica ; Mendes, Milena ; Glória, Helena ; Mateus, Élia ; Marques, Hugo Pinto ; Nolasco, Fernando ; Martins, Américo ; Perdigoto, Rui</creator><creatorcontrib>Rebelo, Carolina Chálim ; Félix, Catarina ; Cardoso, Filipe ; Bagulho, Luís ; Sousa, Mónica ; Mendes, Milena ; Glória, Helena ; Mateus, Élia ; Marques, Hugo Pinto ; Nolasco, Fernando ; Martins, Américo ; Perdigoto, Rui</creatorcontrib><description>BackgroundAlcohol-associated liver disease (ALD) is one of the leading causes of liver transplantation (LT). However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe conducted a cross-sectional study including LT recipients transplanted in 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pre-tested survey including questions on demography, family, employment and social status, and a validated Portuguese translation of the Alcohol Use Disorder Identification Test (AUDIT) was applied via telephone call. Alcohol consumption was defined by patients’ self-report or a positive AUDIT. Informed consent was conveyed by accepting to respond the survey. No donor organs were obtained from executed prisoners or other institutionalized persons.ResultsIn 2019, 122 patients underwent LT at Curry Cabral Hospital. At interview date (June 2021), 19 recipients had died, 2 were being followed abroad, 2 did not consent and 99 answered the survey. Among responders mean±SD age was 57±10-year-old, 70 (70.7%) were males, and 49 (49.5%) underwent ALD-related LT. During a median (IQR) follow-up of 24 (20–26) months post index LT, 22 recipients (22.2%) consumed alcohol: 14 had a drink once a month or less and 8 drank 1–4 times/month. On drinking days, 18 consumed 1–2 drinks and the remainder no more than 3–4 drinks. Only one patient reported to have drunk ≥6 drinks on one occasion. All post-LT drinking recipients were considered low-risk (score <7) as per AUDIT score (median 1 (1–2)). No patient reported alcohol-related problems, whether self or towards others.Among drinking LT recipients, non-ALD-related LT (72.7% vs 44.2%, p=0.018), active smoking (31.8% vs 10.4%, p=0.037) and younger age (53±12 vs 59±10-year-old, p=0.02) were significantly more prevalent than in abstinent LT recipients (table 1).Abstract P018 Table 1ConclusionAt our center, almost ¼ of recipients consumed alcohol early on post-LT, all with a low-risk pattern according to AUDIT score. Interestingly, alcohol consumption was more prevalent in non-ALD-related LT.</description><identifier>ISSN: 0017-5749</identifier><identifier>EISSN: 1468-3288</identifier><identifier>DOI: 10.1136/gutjnl-2021-BASL.27</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Society of Gastroenterology</publisher><subject>Alcohol ; Alcohol use ; Audits ; Beverages ; Cross-sectional studies ; Demography ; Drinking behavior ; Liver diseases ; Liver transplantation ; Liver transplants ; Patients ; Social interactions ; Transplants & implants</subject><ispartof>Gut, 2021-09, Vol.70 (Suppl 3), p.A17-A18</ispartof><rights>Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2021 Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Rebelo, Carolina Chálim</creatorcontrib><creatorcontrib>Félix, Catarina</creatorcontrib><creatorcontrib>Cardoso, Filipe</creatorcontrib><creatorcontrib>Bagulho, Luís</creatorcontrib><creatorcontrib>Sousa, Mónica</creatorcontrib><creatorcontrib>Mendes, Milena</creatorcontrib><creatorcontrib>Glória, Helena</creatorcontrib><creatorcontrib>Mateus, Élia</creatorcontrib><creatorcontrib>Marques, Hugo Pinto</creatorcontrib><creatorcontrib>Nolasco, Fernando</creatorcontrib><creatorcontrib>Martins, Américo</creatorcontrib><creatorcontrib>Perdigoto, Rui</creatorcontrib><title>P018 Alcohol consumption post-liver transplantation at a Portuguese center: a cross-sectional study</title><title>Gut</title><addtitle>Gut</addtitle><description>BackgroundAlcohol-associated liver disease (ALD) is one of the leading causes of liver transplantation (LT). However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe conducted a cross-sectional study including LT recipients transplanted in 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pre-tested survey including questions on demography, family, employment and social status, and a validated Portuguese translation of the Alcohol Use Disorder Identification Test (AUDIT) was applied via telephone call. Alcohol consumption was defined by patients’ self-report or a positive AUDIT. Informed consent was conveyed by accepting to respond the survey. No donor organs were obtained from executed prisoners or other institutionalized persons.ResultsIn 2019, 122 patients underwent LT at Curry Cabral Hospital. At interview date (June 2021), 19 recipients had died, 2 were being followed abroad, 2 did not consent and 99 answered the survey. Among responders mean±SD age was 57±10-year-old, 70 (70.7%) were males, and 49 (49.5%) underwent ALD-related LT. During a median (IQR) follow-up of 24 (20–26) months post index LT, 22 recipients (22.2%) consumed alcohol: 14 had a drink once a month or less and 8 drank 1–4 times/month. On drinking days, 18 consumed 1–2 drinks and the remainder no more than 3–4 drinks. Only one patient reported to have drunk ≥6 drinks on one occasion. All post-LT drinking recipients were considered low-risk (score <7) as per AUDIT score (median 1 (1–2)). No patient reported alcohol-related problems, whether self or towards others.Among drinking LT recipients, non-ALD-related LT (72.7% vs 44.2%, p=0.018), active smoking (31.8% vs 10.4%, p=0.037) and younger age (53±12 vs 59±10-year-old, p=0.02) were significantly more prevalent than in abstinent LT recipients (table 1).Abstract P018 Table 1ConclusionAt our center, almost ¼ of recipients consumed alcohol early on post-LT, all with a low-risk pattern according to AUDIT score. Interestingly, alcohol consumption was more prevalent in non-ALD-related LT.</description><subject>Alcohol</subject><subject>Alcohol use</subject><subject>Audits</subject><subject>Beverages</subject><subject>Cross-sectional studies</subject><subject>Demography</subject><subject>Drinking behavior</subject><subject>Liver diseases</subject><subject>Liver transplantation</subject><subject>Liver transplants</subject><subject>Patients</subject><subject>Social interactions</subject><subject>Transplants & implants</subject><issn>0017-5749</issn><issn>1468-3288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpFkM1KxDAURoMoOI4-gZuC6zg3SdMk7sbBPxhwQF2HNJOOUzJNbVLBnRtf1CexdQRXF-49fHz3IHRO4JIQVsw2faobjylQgq_nT8tLKg7QhOSFxIxKeYgmAERgLnJ1jE5irAFASkUmyK2AyO_Pr7m34TX4zIYm9rs2bUOTtSEm7LfvrstSZ5rYetMk83syKTPZKnSp3_Quusy6JrnualjaLsSIo7MjZ3wWU7_-OEVHlfHRnf3NKXq5vXle3OPl493DYr7E5fCGwCrnXOaGWyKKirsqL6wtjWXgTLVeK84YMaVhgpSCWa7AOlpxWSkwwpKyVGyKLva5bRfehmJJ16HvhhpRUy6YgBwUDNRsT5W7-h8goEeXeu9Sjy716FJTwX4A9_1sDg</recordid><startdate>20210917</startdate><enddate>20210917</enddate><creator>Rebelo, Carolina Chálim</creator><creator>Félix, Catarina</creator><creator>Cardoso, Filipe</creator><creator>Bagulho, Luís</creator><creator>Sousa, Mónica</creator><creator>Mendes, Milena</creator><creator>Glória, Helena</creator><creator>Mateus, Élia</creator><creator>Marques, Hugo Pinto</creator><creator>Nolasco, Fernando</creator><creator>Martins, Américo</creator><creator>Perdigoto, Rui</creator><general>BMJ Publishing Group Ltd and British Society of Gastroenterology</general><general>BMJ Publishing Group LTD</general><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>20210917</creationdate><title>P018 Alcohol consumption post-liver transplantation at a Portuguese center: a cross-sectional study</title><author>Rebelo, Carolina Chálim ; Félix, Catarina ; Cardoso, Filipe ; Bagulho, Luís ; Sousa, Mónica ; Mendes, Milena ; Glória, Helena ; Mateus, Élia ; Marques, Hugo Pinto ; Nolasco, Fernando ; Martins, Américo ; Perdigoto, Rui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b1137-945584a5c176f5ef46ccbac30eafdd95331aba371b73c590ce2f58f90a7c1bb93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Alcohol</topic><topic>Alcohol use</topic><topic>Audits</topic><topic>Beverages</topic><topic>Cross-sectional studies</topic><topic>Demography</topic><topic>Drinking behavior</topic><topic>Liver diseases</topic><topic>Liver transplantation</topic><topic>Liver transplants</topic><topic>Patients</topic><topic>Social interactions</topic><topic>Transplants & implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rebelo, Carolina Chálim</creatorcontrib><creatorcontrib>Félix, Catarina</creatorcontrib><creatorcontrib>Cardoso, Filipe</creatorcontrib><creatorcontrib>Bagulho, Luís</creatorcontrib><creatorcontrib>Sousa, Mónica</creatorcontrib><creatorcontrib>Mendes, Milena</creatorcontrib><creatorcontrib>Glória, Helena</creatorcontrib><creatorcontrib>Mateus, Élia</creatorcontrib><creatorcontrib>Marques, Hugo Pinto</creatorcontrib><creatorcontrib>Nolasco, Fernando</creatorcontrib><creatorcontrib>Martins, Américo</creatorcontrib><creatorcontrib>Perdigoto, Rui</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Gut</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rebelo, Carolina Chálim</au><au>Félix, Catarina</au><au>Cardoso, Filipe</au><au>Bagulho, Luís</au><au>Sousa, Mónica</au><au>Mendes, Milena</au><au>Glória, Helena</au><au>Mateus, Élia</au><au>Marques, Hugo Pinto</au><au>Nolasco, Fernando</au><au>Martins, Américo</au><au>Perdigoto, Rui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>P018 Alcohol consumption post-liver transplantation at a Portuguese center: a cross-sectional study</atitle><jtitle>Gut</jtitle><stitle>Gut</stitle><date>2021-09-17</date><risdate>2021</risdate><volume>70</volume><issue>Suppl 3</issue><spage>A17</spage><epage>A18</epage><pages>A17-A18</pages><issn>0017-5749</issn><eissn>1468-3288</eissn><abstract>BackgroundAlcohol-associated liver disease (ALD) is one of the leading causes of liver transplantation (LT). However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe conducted a cross-sectional study including LT recipients transplanted in 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pre-tested survey including questions on demography, family, employment and social status, and a validated Portuguese translation of the Alcohol Use Disorder Identification Test (AUDIT) was applied via telephone call. Alcohol consumption was defined by patients’ self-report or a positive AUDIT. Informed consent was conveyed by accepting to respond the survey. No donor organs were obtained from executed prisoners or other institutionalized persons.ResultsIn 2019, 122 patients underwent LT at Curry Cabral Hospital. At interview date (June 2021), 19 recipients had died, 2 were being followed abroad, 2 did not consent and 99 answered the survey. Among responders mean±SD age was 57±10-year-old, 70 (70.7%) were males, and 49 (49.5%) underwent ALD-related LT. During a median (IQR) follow-up of 24 (20–26) months post index LT, 22 recipients (22.2%) consumed alcohol: 14 had a drink once a month or less and 8 drank 1–4 times/month. On drinking days, 18 consumed 1–2 drinks and the remainder no more than 3–4 drinks. Only one patient reported to have drunk ≥6 drinks on one occasion. All post-LT drinking recipients were considered low-risk (score <7) as per AUDIT score (median 1 (1–2)). No patient reported alcohol-related problems, whether self or towards others.Among drinking LT recipients, non-ALD-related LT (72.7% vs 44.2%, p=0.018), active smoking (31.8% vs 10.4%, p=0.037) and younger age (53±12 vs 59±10-year-old, p=0.02) were significantly more prevalent than in abstinent LT recipients (table 1).Abstract P018 Table 1ConclusionAt our center, almost ¼ of recipients consumed alcohol early on post-LT, all with a low-risk pattern according to AUDIT score. Interestingly, alcohol consumption was more prevalent in non-ALD-related LT.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Society of Gastroenterology</pub><doi>10.1136/gutjnl-2021-BASL.27</doi><oa>free_for_read</oa></addata></record> |
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subjects | Alcohol Alcohol use Audits Beverages Cross-sectional studies Demography Drinking behavior Liver diseases Liver transplantation Liver transplants Patients Social interactions Transplants & implants |
title | P018 Alcohol consumption post-liver transplantation at a Portuguese center: a cross-sectional study |
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