P018 Alcohol consumption post-liver transplantation at a Portuguese center: a cross-sectional study

BackgroundAlcohol-associated liver disease (ALD) is one of the leading causes of liver transplantation (LT). However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe cond...

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Veröffentlicht in:Gut 2021-09, Vol.70 (Suppl 3), p.A17-A18
Hauptverfasser: Rebelo, Carolina Chálim, Félix, Catarina, Cardoso, Filipe, Bagulho, Luís, Sousa, Mónica, Mendes, Milena, Glória, Helena, Mateus, Élia, Marques, Hugo Pinto, Nolasco, Fernando, Martins, Américo, Perdigoto, Rui
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container_end_page A18
container_issue Suppl 3
container_start_page A17
container_title Gut
container_volume 70
creator Rebelo, Carolina Chálim
Félix, Catarina
Cardoso, Filipe
Bagulho, Luís
Sousa, Mónica
Mendes, Milena
Glória, Helena
Mateus, Élia
Marques, Hugo Pinto
Nolasco, Fernando
Martins, Américo
Perdigoto, Rui
description BackgroundAlcohol-associated liver disease (ALD) is one of the leading causes of liver transplantation (LT). However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe conducted a cross-sectional study including LT recipients transplanted in 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pre-tested survey including questions on demography, family, employment and social status, and a validated Portuguese translation of the Alcohol Use Disorder Identification Test (AUDIT) was applied via telephone call. Alcohol consumption was defined by patients’ self-report or a positive AUDIT. Informed consent was conveyed by accepting to respond the survey. No donor organs were obtained from executed prisoners or other institutionalized persons.ResultsIn 2019, 122 patients underwent LT at Curry Cabral Hospital. At interview date (June 2021), 19 recipients had died, 2 were being followed abroad, 2 did not consent and 99 answered the survey. Among responders mean±SD age was 57±10-year-old, 70 (70.7%) were males, and 49 (49.5%) underwent ALD-related LT. During a median (IQR) follow-up of 24 (20–26) months post index LT, 22 recipients (22.2%) consumed alcohol: 14 had a drink once a month or less and 8 drank 1–4 times/month. On drinking days, 18 consumed 1–2 drinks and the remainder no more than 3–4 drinks. Only one patient reported to have drunk ≥6 drinks on one occasion. All post-LT drinking recipients were considered low-risk (score
doi_str_mv 10.1136/gutjnl-2021-BASL.27
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However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe conducted a cross-sectional study including LT recipients transplanted in 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pre-tested survey including questions on demography, family, employment and social status, and a validated Portuguese translation of the Alcohol Use Disorder Identification Test (AUDIT) was applied via telephone call. Alcohol consumption was defined by patients’ self-report or a positive AUDIT. Informed consent was conveyed by accepting to respond the survey. No donor organs were obtained from executed prisoners or other institutionalized persons.ResultsIn 2019, 122 patients underwent LT at Curry Cabral Hospital. At interview date (June 2021), 19 recipients had died, 2 were being followed abroad, 2 did not consent and 99 answered the survey. Among responders mean±SD age was 57±10-year-old, 70 (70.7%) were males, and 49 (49.5%) underwent ALD-related LT. During a median (IQR) follow-up of 24 (20–26) months post index LT, 22 recipients (22.2%) consumed alcohol: 14 had a drink once a month or less and 8 drank 1–4 times/month. On drinking days, 18 consumed 1–2 drinks and the remainder no more than 3–4 drinks. Only one patient reported to have drunk ≥6 drinks on one occasion. All post-LT drinking recipients were considered low-risk (score &lt;7) as per AUDIT score (median 1 (1–2)). No patient reported alcohol-related problems, whether self or towards others.Among drinking LT recipients, non-ALD-related LT (72.7% vs 44.2%, p=0.018), active smoking (31.8% vs 10.4%, p=0.037) and younger age (53±12 vs 59±10-year-old, p=0.02) were significantly more prevalent than in abstinent LT recipients (table 1).Abstract P018 Table 1ConclusionAt our center, almost ¼ of recipients consumed alcohol early on post-LT, all with a low-risk pattern according to AUDIT score. Interestingly, alcohol consumption was more prevalent in non-ALD-related LT.</description><identifier>ISSN: 0017-5749</identifier><identifier>EISSN: 1468-3288</identifier><identifier>DOI: 10.1136/gutjnl-2021-BASL.27</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Society of Gastroenterology</publisher><subject>Alcohol ; Alcohol use ; Audits ; Beverages ; Cross-sectional studies ; Demography ; Drinking behavior ; Liver diseases ; Liver transplantation ; Liver transplants ; Patients ; Social interactions ; Transplants &amp; implants</subject><ispartof>Gut, 2021-09, Vol.70 (Suppl 3), p.A17-A18</ispartof><rights>Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2021 Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Rebelo, Carolina Chálim</creatorcontrib><creatorcontrib>Félix, Catarina</creatorcontrib><creatorcontrib>Cardoso, Filipe</creatorcontrib><creatorcontrib>Bagulho, Luís</creatorcontrib><creatorcontrib>Sousa, Mónica</creatorcontrib><creatorcontrib>Mendes, Milena</creatorcontrib><creatorcontrib>Glória, Helena</creatorcontrib><creatorcontrib>Mateus, Élia</creatorcontrib><creatorcontrib>Marques, Hugo Pinto</creatorcontrib><creatorcontrib>Nolasco, Fernando</creatorcontrib><creatorcontrib>Martins, Américo</creatorcontrib><creatorcontrib>Perdigoto, Rui</creatorcontrib><title>P018 Alcohol consumption post-liver transplantation at a Portuguese center: a cross-sectional study</title><title>Gut</title><addtitle>Gut</addtitle><description>BackgroundAlcohol-associated liver disease (ALD) is one of the leading causes of liver transplantation (LT). However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe conducted a cross-sectional study including LT recipients transplanted in 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pre-tested survey including questions on demography, family, employment and social status, and a validated Portuguese translation of the Alcohol Use Disorder Identification Test (AUDIT) was applied via telephone call. Alcohol consumption was defined by patients’ self-report or a positive AUDIT. Informed consent was conveyed by accepting to respond the survey. No donor organs were obtained from executed prisoners or other institutionalized persons.ResultsIn 2019, 122 patients underwent LT at Curry Cabral Hospital. At interview date (June 2021), 19 recipients had died, 2 were being followed abroad, 2 did not consent and 99 answered the survey. Among responders mean±SD age was 57±10-year-old, 70 (70.7%) were males, and 49 (49.5%) underwent ALD-related LT. During a median (IQR) follow-up of 24 (20–26) months post index LT, 22 recipients (22.2%) consumed alcohol: 14 had a drink once a month or less and 8 drank 1–4 times/month. On drinking days, 18 consumed 1–2 drinks and the remainder no more than 3–4 drinks. Only one patient reported to have drunk ≥6 drinks on one occasion. All post-LT drinking recipients were considered low-risk (score &lt;7) as per AUDIT score (median 1 (1–2)). No patient reported alcohol-related problems, whether self or towards others.Among drinking LT recipients, non-ALD-related LT (72.7% vs 44.2%, p=0.018), active smoking (31.8% vs 10.4%, p=0.037) and younger age (53±12 vs 59±10-year-old, p=0.02) were significantly more prevalent than in abstinent LT recipients (table 1).Abstract P018 Table 1ConclusionAt our center, almost ¼ of recipients consumed alcohol early on post-LT, all with a low-risk pattern according to AUDIT score. 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Félix, Catarina ; Cardoso, Filipe ; Bagulho, Luís ; Sousa, Mónica ; Mendes, Milena ; Glória, Helena ; Mateus, Élia ; Marques, Hugo Pinto ; Nolasco, Fernando ; Martins, Américo ; Perdigoto, Rui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b1137-945584a5c176f5ef46ccbac30eafdd95331aba371b73c590ce2f58f90a7c1bb93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Alcohol</topic><topic>Alcohol use</topic><topic>Audits</topic><topic>Beverages</topic><topic>Cross-sectional studies</topic><topic>Demography</topic><topic>Drinking behavior</topic><topic>Liver diseases</topic><topic>Liver transplantation</topic><topic>Liver transplants</topic><topic>Patients</topic><topic>Social interactions</topic><topic>Transplants &amp; implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rebelo, Carolina Chálim</creatorcontrib><creatorcontrib>Félix, Catarina</creatorcontrib><creatorcontrib>Cardoso, Filipe</creatorcontrib><creatorcontrib>Bagulho, Luís</creatorcontrib><creatorcontrib>Sousa, Mónica</creatorcontrib><creatorcontrib>Mendes, Milena</creatorcontrib><creatorcontrib>Glória, Helena</creatorcontrib><creatorcontrib>Mateus, Élia</creatorcontrib><creatorcontrib>Marques, Hugo Pinto</creatorcontrib><creatorcontrib>Nolasco, Fernando</creatorcontrib><creatorcontrib>Martins, Américo</creatorcontrib><creatorcontrib>Perdigoto, Rui</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; 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However, LT listing in ALD remains challenging regarding the risk of alcohol relapse post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center.MethodsWe conducted a cross-sectional study including LT recipients transplanted in 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pre-tested survey including questions on demography, family, employment and social status, and a validated Portuguese translation of the Alcohol Use Disorder Identification Test (AUDIT) was applied via telephone call. Alcohol consumption was defined by patients’ self-report or a positive AUDIT. Informed consent was conveyed by accepting to respond the survey. No donor organs were obtained from executed prisoners or other institutionalized persons.ResultsIn 2019, 122 patients underwent LT at Curry Cabral Hospital. At interview date (June 2021), 19 recipients had died, 2 were being followed abroad, 2 did not consent and 99 answered the survey. Among responders mean±SD age was 57±10-year-old, 70 (70.7%) were males, and 49 (49.5%) underwent ALD-related LT. During a median (IQR) follow-up of 24 (20–26) months post index LT, 22 recipients (22.2%) consumed alcohol: 14 had a drink once a month or less and 8 drank 1–4 times/month. On drinking days, 18 consumed 1–2 drinks and the remainder no more than 3–4 drinks. Only one patient reported to have drunk ≥6 drinks on one occasion. All post-LT drinking recipients were considered low-risk (score &lt;7) as per AUDIT score (median 1 (1–2)). No patient reported alcohol-related problems, whether self or towards others.Among drinking LT recipients, non-ALD-related LT (72.7% vs 44.2%, p=0.018), active smoking (31.8% vs 10.4%, p=0.037) and younger age (53±12 vs 59±10-year-old, p=0.02) were significantly more prevalent than in abstinent LT recipients (table 1).Abstract P018 Table 1ConclusionAt our center, almost ¼ of recipients consumed alcohol early on post-LT, all with a low-risk pattern according to AUDIT score. Interestingly, alcohol consumption was more prevalent in non-ALD-related LT.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Society of Gastroenterology</pub><doi>10.1136/gutjnl-2021-BASL.27</doi><oa>free_for_read</oa></addata></record>
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subjects Alcohol
Alcohol use
Audits
Beverages
Cross-sectional studies
Demography
Drinking behavior
Liver diseases
Liver transplantation
Liver transplants
Patients
Social interactions
Transplants & implants
title P018 Alcohol consumption post-liver transplantation at a Portuguese center: a cross-sectional study
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