Methoxphenidine (MXP) induced abnormalities: Addictive and schizophrenia‐related behaviours based on an imbalance of neurochemicals in the brain

Background and Purpose Methoxphenidine is a dissociative‐based novel psychoactive designer drug. Although fatal accidents from methoxphenidine abuse have been reported, recreational use of the drug continues. We aim to provide scientific supportfor legal regulation of recreational abuse of methoxphe...

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Veröffentlicht in:	British journal of pharmacology 2021-10, Vol.178 (19), p.3869-3887
Hauptverfasser:	Hur, Kwang‐Hyun, Kim, Seong‐Eon, Ma, Shi‐Xun, Lee, Bo‐Ram, Ko, Yong‐Hyun, Seo, Jee‐Yeon, Kim, Seon‐Kyung, Kim, Young‐Jung, Sung, Su‐Jeong, Lee, Youyoung, Jung, Young Hoon, Lee, Yong‐Sup, Lee, Seok‐Yong, Jang, Choon‐Gon
Format:	Artikel
Sprache:	eng
Schlagworte:	addiction Addictive behaviors Animal diseases Animal models Brain Cognitive ability dissociative drug Emotional behavior Hippocampus Hyperactivity Impulsive behavior Intravenous administration Mental disorders methoxphenidine MXP NMDA receptor antagonist Nucleus accumbens Open-field behavior Pattern recognition Place preference conditioning Prefrontal cortex Reinforcement Schizophrenia Social interactions Withdrawal
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