Non-invasive microwave sensor for the detection of the cell culture medium residues
A metallic circular tapped split ring resonator (CT-SRR) coupled with coplanar waveguide (CPW) are designed and fabricated for the non-invasive measurement of the cell (fibroblasts and adipocytes) culture medium residues (MRs), comprising remaining nutrients (glucose and electrolytes), serum, and ot...
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| Veröffentlicht in: | Journal of physics. Conference series 2019-11, Vol.1380 (1), p.12054 |
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| creator | Wanthong, A Harnsoongnoen, S |
| description | A metallic circular tapped split ring resonator (CT-SRR) coupled with coplanar waveguide (CPW) are designed and fabricated for the non-invasive measurement of the cell (fibroblasts and adipocytes) culture medium residues (MRs), comprising remaining nutrients (glucose and electrolytes), serum, and other substances following cell cultures. Pre-culturing MRs were prepared with the same standard formulas and divided into four cases, i) pre - MRs with serum, ii) pre-MRs with serum and herb extract, iii) pre-MRs with serum and hormones and iv) pre-MRs with serum, hormones and herb extract. The four cases of culturing MR preparations are measured and analyzed by the proposed microwave sensor through transmission coefficient (S21) in the frequency range from 1.5 GHz - 2.5 GHz. The experimental results show that the highest of S21 and cells fat accumulation activity in case (iv) which related to the lowest remaining nutrients. The order amplitude of S21 at 1.96 GHz with material under tests (MUTs) at 1.96 GHz as follows: case (iv) > case (ii) > case (i) > case (iii) > DI water > air. The results demonstrate the feasibility of a non-invasive microwave based biochemistry sensor technology. |
| doi_str_mv | 10.1088/1742-6596/1380/1/012054 |
| format | Article |
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Pre-culturing MRs were prepared with the same standard formulas and divided into four cases, i) pre - MRs with serum, ii) pre-MRs with serum and herb extract, iii) pre-MRs with serum and hormones and iv) pre-MRs with serum, hormones and herb extract. The four cases of culturing MR preparations are measured and analyzed by the proposed microwave sensor through transmission coefficient (S21) in the frequency range from 1.5 GHz - 2.5 GHz. The experimental results show that the highest of S21 and cells fat accumulation activity in case (iv) which related to the lowest remaining nutrients. The order amplitude of S21 at 1.96 GHz with material under tests (MUTs) at 1.96 GHz as follows: case (iv) > case (ii) > case (i) > case (iii) > DI water > air. The results demonstrate the feasibility of a non-invasive microwave based biochemistry sensor technology.</description><identifier>ISSN: 1742-6588</identifier><identifier>EISSN: 1742-6596</identifier><identifier>DOI: 10.1088/1742-6596/1380/1/012054</identifier><language>eng</language><publisher>Bristol: IOP Publishing</publisher><subject>Coplanar waveguides ; Electrolytes ; Electrolytic cells ; Fibroblasts ; Frequency ranges ; Herbs ; Hormones ; Microwave sensors ; Nutrients ; Physics ; Residues ; Sensors</subject><ispartof>Journal of physics. Conference series, 2019-11, Vol.1380 (1), p.12054</ispartof><rights>Published under licence by IOP Publishing Ltd</rights><rights>2019. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c359t-e6710feacad67ce80f9a03081e5765a2303b85dd8b657935c3ab31e25f79f243</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://iopscience.iop.org/article/10.1088/1742-6596/1380/1/012054/pdf$$EPDF$$P50$$Giop$$Hfree_for_read</linktopdf><link.rule.ids>314,780,784,27924,27925,38868,38890,53840,53867</link.rule.ids></links><search><creatorcontrib>Wanthong, A</creatorcontrib><creatorcontrib>Harnsoongnoen, S</creatorcontrib><title>Non-invasive microwave sensor for the detection of the cell culture medium residues</title><title>Journal of physics. Conference series</title><addtitle>J. Phys.: Conf. Ser</addtitle><description>A metallic circular tapped split ring resonator (CT-SRR) coupled with coplanar waveguide (CPW) are designed and fabricated for the non-invasive measurement of the cell (fibroblasts and adipocytes) culture medium residues (MRs), comprising remaining nutrients (glucose and electrolytes), serum, and other substances following cell cultures. Pre-culturing MRs were prepared with the same standard formulas and divided into four cases, i) pre - MRs with serum, ii) pre-MRs with serum and herb extract, iii) pre-MRs with serum and hormones and iv) pre-MRs with serum, hormones and herb extract. The four cases of culturing MR preparations are measured and analyzed by the proposed microwave sensor through transmission coefficient (S21) in the frequency range from 1.5 GHz - 2.5 GHz. The experimental results show that the highest of S21 and cells fat accumulation activity in case (iv) which related to the lowest remaining nutrients. The order amplitude of S21 at 1.96 GHz with material under tests (MUTs) at 1.96 GHz as follows: case (iv) > case (ii) > case (i) > case (iii) > DI water > air. The results demonstrate the feasibility of a non-invasive microwave based biochemistry sensor technology.</description><subject>Coplanar waveguides</subject><subject>Electrolytes</subject><subject>Electrolytic cells</subject><subject>Fibroblasts</subject><subject>Frequency ranges</subject><subject>Herbs</subject><subject>Hormones</subject><subject>Microwave sensors</subject><subject>Nutrients</subject><subject>Physics</subject><subject>Residues</subject><subject>Sensors</subject><issn>1742-6588</issn><issn>1742-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>O3W</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNqFkF9LwzAUxYMoOKefwYJvQm3SNE36KMO_DBW295ClN5ixNTVpJ357UysTQTBwyeXmd-4hB6Fzgq8IFiIjvMjTklVlRqjAGckwyTErDtBk_3K474U4RichrDGm8fAJWjy5JrXNTgW7g2RrtXfvKnYBmuB8YmJ1r5DU0IHurGsSZ74GGjabRPebrvdRBrXtt4mHYOsewik6MmoT4Oz7nqLl7c1ydp_On-8eZtfzVFNWdSmUnGADSqu65BoENpXCFAsCjJdM5RTTlWB1LVYl4xVlmqoVJZAzwyuTF3SKLsa1rXdv0baTa9f7JjrKnJWiwJQxGik-UvFnIXgwsvV2q_yHJFgOAcohGjnEJIcAJZFjgFF5OSqta39WP77MFr9B2dYmwvQP-D-LT6EagDg</recordid><startdate>20191101</startdate><enddate>20191101</enddate><creator>Wanthong, A</creator><creator>Harnsoongnoen, S</creator><general>IOP Publishing</general><scope>O3W</scope><scope>TSCCA</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>H8D</scope><scope>HCIFZ</scope><scope>L7M</scope><scope>P5Z</scope><scope>P62</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20191101</creationdate><title>Non-invasive microwave sensor for the detection of the cell culture medium residues</title><author>Wanthong, A ; Harnsoongnoen, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-e6710feacad67ce80f9a03081e5765a2303b85dd8b657935c3ab31e25f79f243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Coplanar waveguides</topic><topic>Electrolytes</topic><topic>Electrolytic cells</topic><topic>Fibroblasts</topic><topic>Frequency ranges</topic><topic>Herbs</topic><topic>Hormones</topic><topic>Microwave sensors</topic><topic>Nutrients</topic><topic>Physics</topic><topic>Residues</topic><topic>Sensors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wanthong, A</creatorcontrib><creatorcontrib>Harnsoongnoen, S</creatorcontrib><collection>Institute of Physics Open Access Journal Titles</collection><collection>IOPscience (Open Access)</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Aerospace Database</collection><collection>SciTech Premium Collection</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Journal of physics. Conference series</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wanthong, A</au><au>Harnsoongnoen, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Non-invasive microwave sensor for the detection of the cell culture medium residues</atitle><jtitle>Journal of physics. Conference series</jtitle><addtitle>J. Phys.: Conf. Ser</addtitle><date>2019-11-01</date><risdate>2019</risdate><volume>1380</volume><issue>1</issue><spage>12054</spage><pages>12054-</pages><issn>1742-6588</issn><eissn>1742-6596</eissn><abstract>A metallic circular tapped split ring resonator (CT-SRR) coupled with coplanar waveguide (CPW) are designed and fabricated for the non-invasive measurement of the cell (fibroblasts and adipocytes) culture medium residues (MRs), comprising remaining nutrients (glucose and electrolytes), serum, and other substances following cell cultures. Pre-culturing MRs were prepared with the same standard formulas and divided into four cases, i) pre - MRs with serum, ii) pre-MRs with serum and herb extract, iii) pre-MRs with serum and hormones and iv) pre-MRs with serum, hormones and herb extract. The four cases of culturing MR preparations are measured and analyzed by the proposed microwave sensor through transmission coefficient (S21) in the frequency range from 1.5 GHz - 2.5 GHz. The experimental results show that the highest of S21 and cells fat accumulation activity in case (iv) which related to the lowest remaining nutrients. The order amplitude of S21 at 1.96 GHz with material under tests (MUTs) at 1.96 GHz as follows: case (iv) > case (ii) > case (i) > case (iii) > DI water > air. The results demonstrate the feasibility of a non-invasive microwave based biochemistry sensor technology.</abstract><cop>Bristol</cop><pub>IOP Publishing</pub><doi>10.1088/1742-6596/1380/1/012054</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Coplanar waveguides Electrolytes Electrolytic cells Fibroblasts Frequency ranges Herbs Hormones Microwave sensors Nutrients Physics Residues Sensors |
| title | Non-invasive microwave sensor for the detection of the cell culture medium residues |
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