Preparation and Characterization of a Hard Capsule Based on Oxidized Rice Starch and Cellulose Nanocrystals
A hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared by a dipping method and the glycerol and carrageenan are used as a plasticizer and gelling agent in the ORS/CNC gel solution, respectively. The viscosity of gel solution that is suitable for film‐forming/...
Gespeichert in:
Veröffentlicht in: | Starch - Stärke 2021-09, Vol.73 (9-10), p.n/a |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | n/a |
---|---|
container_issue | 9-10 |
container_start_page | |
container_title | Starch - Stärke |
container_volume | 73 |
creator | Chen, QiJie Zhao, YaLan Zong, ZhangYang You, Na Zhang, Peng |
description | A hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared by a dipping method and the glycerol and carrageenan are used as a plasticizer and gelling agent in the ORS/CNC gel solution, respectively. The viscosity of gel solution that is suitable for film‐forming/capsule‐forming is analyzed. When the content of CNC is 8.0%, the tensile strength of the ORS/CNC composite film is 10.09 MPa and increased by 196.0%. The loss on drying and the disintegration time of the ORS/CNC capsules are also investigated. The ORS/CNC capsules are analyzed by Fourier Transform Infrared spectroscopy (FTIR), X‐Ray Diffraction (XRD), and Scanning Electron Microscopy (SEM). The results show that the ORS and CNC have good compatibility and good film‐forming ability and can be used as excipients to prepare the hard capsules.
A kind of hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared and characterized. The ORS and CNC has good compatibility and good film‐forming ability and can be used as excipients to prepare hard capsules. |
doi_str_mv | 10.1002/star.202100085 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2568186744</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2568186744</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2475-fe40c9314eb92059b5e904737943945fb901e1dd5a2a5328e3c714c16417275b3</originalsourceid><addsrcrecordid>eNqFUD1PwzAQtRBIlMLKbIk5xXbsOB5LBRSpAtQWic1ynIuaEpJgJ4L21-MqCEam-3rv3d1D6JKSCSWEXfvOuAkjLBQkFUdoRAWjUSzV6zEaERKnkSIiOUVn3m8JSYTkdITenh20xpmubGps6hzPNqGyHbhyPzSbAhs8Ny6MTOv7CvCN8ZDjMHr6KvNyH_JlaQGvwn67GUSgqvqq8YAfTd1Ytwu3Vf4cnRQhwMVPHKOXu9v1bB4tnu4fZtNFZBmXIiqAE6tiyiFTjAiVCVCEy_AIjxUXRaYIBZrnwjAjYpZCbCXlliacSiZFFo_R1aDbuuajB9_pbdO7OqzUTCQpTRPJeUBNBpR1jfcOCt268t24naZEHwzVB0P1r6GBoAbCZ1nB7h-0Xq2nyz_uNyVZeaI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2568186744</pqid></control><display><type>article</type><title>Preparation and Characterization of a Hard Capsule Based on Oxidized Rice Starch and Cellulose Nanocrystals</title><source>Wiley Online Library</source><creator>Chen, QiJie ; Zhao, YaLan ; Zong, ZhangYang ; You, Na ; Zhang, Peng</creator><creatorcontrib>Chen, QiJie ; Zhao, YaLan ; Zong, ZhangYang ; You, Na ; Zhang, Peng</creatorcontrib><description>A hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared by a dipping method and the glycerol and carrageenan are used as a plasticizer and gelling agent in the ORS/CNC gel solution, respectively. The viscosity of gel solution that is suitable for film‐forming/capsule‐forming is analyzed. When the content of CNC is 8.0%, the tensile strength of the ORS/CNC composite film is 10.09 MPa and increased by 196.0%. The loss on drying and the disintegration time of the ORS/CNC capsules are also investigated. The ORS/CNC capsules are analyzed by Fourier Transform Infrared spectroscopy (FTIR), X‐Ray Diffraction (XRD), and Scanning Electron Microscopy (SEM). The results show that the ORS and CNC have good compatibility and good film‐forming ability and can be used as excipients to prepare the hard capsules.
A kind of hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared and characterized. The ORS and CNC has good compatibility and good film‐forming ability and can be used as excipients to prepare hard capsules.</description><identifier>ISSN: 0038-9056</identifier><identifier>EISSN: 1521-379X</identifier><identifier>DOI: 10.1002/star.202100085</identifier><language>eng</language><publisher>Weinheim: Wiley Subscription Services, Inc</publisher><subject>Carrageenan ; Cellulose ; cellulose nanocrystals ; Crystals ; Disintegration ; disintegration time ; Drying ; Fourier transforms ; Glycerol ; hard capsules ; Infrared analysis ; Infrared spectroscopy ; Nanocrystals ; oxidized rice starch ; Scanning electron microscopy ; Starch ; Tensile strength</subject><ispartof>Starch - Stärke, 2021-09, Vol.73 (9-10), p.n/a</ispartof><rights>2021 Wiley‐VCH GmbH</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2475-fe40c9314eb92059b5e904737943945fb901e1dd5a2a5328e3c714c16417275b3</citedby><cites>FETCH-LOGICAL-c2475-fe40c9314eb92059b5e904737943945fb901e1dd5a2a5328e3c714c16417275b3</cites><orcidid>0000-0001-9996-8051</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fstar.202100085$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fstar.202100085$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids></links><search><creatorcontrib>Chen, QiJie</creatorcontrib><creatorcontrib>Zhao, YaLan</creatorcontrib><creatorcontrib>Zong, ZhangYang</creatorcontrib><creatorcontrib>You, Na</creatorcontrib><creatorcontrib>Zhang, Peng</creatorcontrib><title>Preparation and Characterization of a Hard Capsule Based on Oxidized Rice Starch and Cellulose Nanocrystals</title><title>Starch - Stärke</title><description>A hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared by a dipping method and the glycerol and carrageenan are used as a plasticizer and gelling agent in the ORS/CNC gel solution, respectively. The viscosity of gel solution that is suitable for film‐forming/capsule‐forming is analyzed. When the content of CNC is 8.0%, the tensile strength of the ORS/CNC composite film is 10.09 MPa and increased by 196.0%. The loss on drying and the disintegration time of the ORS/CNC capsules are also investigated. The ORS/CNC capsules are analyzed by Fourier Transform Infrared spectroscopy (FTIR), X‐Ray Diffraction (XRD), and Scanning Electron Microscopy (SEM). The results show that the ORS and CNC have good compatibility and good film‐forming ability and can be used as excipients to prepare the hard capsules.
A kind of hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared and characterized. The ORS and CNC has good compatibility and good film‐forming ability and can be used as excipients to prepare hard capsules.</description><subject>Carrageenan</subject><subject>Cellulose</subject><subject>cellulose nanocrystals</subject><subject>Crystals</subject><subject>Disintegration</subject><subject>disintegration time</subject><subject>Drying</subject><subject>Fourier transforms</subject><subject>Glycerol</subject><subject>hard capsules</subject><subject>Infrared analysis</subject><subject>Infrared spectroscopy</subject><subject>Nanocrystals</subject><subject>oxidized rice starch</subject><subject>Scanning electron microscopy</subject><subject>Starch</subject><subject>Tensile strength</subject><issn>0038-9056</issn><issn>1521-379X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNqFUD1PwzAQtRBIlMLKbIk5xXbsOB5LBRSpAtQWic1ynIuaEpJgJ4L21-MqCEam-3rv3d1D6JKSCSWEXfvOuAkjLBQkFUdoRAWjUSzV6zEaERKnkSIiOUVn3m8JSYTkdITenh20xpmubGps6hzPNqGyHbhyPzSbAhs8Ny6MTOv7CvCN8ZDjMHr6KvNyH_JlaQGvwn67GUSgqvqq8YAfTd1Ytwu3Vf4cnRQhwMVPHKOXu9v1bB4tnu4fZtNFZBmXIiqAE6tiyiFTjAiVCVCEy_AIjxUXRaYIBZrnwjAjYpZCbCXlliacSiZFFo_R1aDbuuajB9_pbdO7OqzUTCQpTRPJeUBNBpR1jfcOCt268t24naZEHwzVB0P1r6GBoAbCZ1nB7h-0Xq2nyz_uNyVZeaI</recordid><startdate>202109</startdate><enddate>202109</enddate><creator>Chen, QiJie</creator><creator>Zhao, YaLan</creator><creator>Zong, ZhangYang</creator><creator>You, Na</creator><creator>Zhang, Peng</creator><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0001-9996-8051</orcidid></search><sort><creationdate>202109</creationdate><title>Preparation and Characterization of a Hard Capsule Based on Oxidized Rice Starch and Cellulose Nanocrystals</title><author>Chen, QiJie ; Zhao, YaLan ; Zong, ZhangYang ; You, Na ; Zhang, Peng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2475-fe40c9314eb92059b5e904737943945fb901e1dd5a2a5328e3c714c16417275b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Carrageenan</topic><topic>Cellulose</topic><topic>cellulose nanocrystals</topic><topic>Crystals</topic><topic>Disintegration</topic><topic>disintegration time</topic><topic>Drying</topic><topic>Fourier transforms</topic><topic>Glycerol</topic><topic>hard capsules</topic><topic>Infrared analysis</topic><topic>Infrared spectroscopy</topic><topic>Nanocrystals</topic><topic>oxidized rice starch</topic><topic>Scanning electron microscopy</topic><topic>Starch</topic><topic>Tensile strength</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, QiJie</creatorcontrib><creatorcontrib>Zhao, YaLan</creatorcontrib><creatorcontrib>Zong, ZhangYang</creatorcontrib><creatorcontrib>You, Na</creatorcontrib><creatorcontrib>Zhang, Peng</creatorcontrib><collection>CrossRef</collection><jtitle>Starch - Stärke</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, QiJie</au><au>Zhao, YaLan</au><au>Zong, ZhangYang</au><au>You, Na</au><au>Zhang, Peng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preparation and Characterization of a Hard Capsule Based on Oxidized Rice Starch and Cellulose Nanocrystals</atitle><jtitle>Starch - Stärke</jtitle><date>2021-09</date><risdate>2021</risdate><volume>73</volume><issue>9-10</issue><epage>n/a</epage><issn>0038-9056</issn><eissn>1521-379X</eissn><abstract>A hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared by a dipping method and the glycerol and carrageenan are used as a plasticizer and gelling agent in the ORS/CNC gel solution, respectively. The viscosity of gel solution that is suitable for film‐forming/capsule‐forming is analyzed. When the content of CNC is 8.0%, the tensile strength of the ORS/CNC composite film is 10.09 MPa and increased by 196.0%. The loss on drying and the disintegration time of the ORS/CNC capsules are also investigated. The ORS/CNC capsules are analyzed by Fourier Transform Infrared spectroscopy (FTIR), X‐Ray Diffraction (XRD), and Scanning Electron Microscopy (SEM). The results show that the ORS and CNC have good compatibility and good film‐forming ability and can be used as excipients to prepare the hard capsules.
A kind of hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared and characterized. The ORS and CNC has good compatibility and good film‐forming ability and can be used as excipients to prepare hard capsules.</abstract><cop>Weinheim</cop><pub>Wiley Subscription Services, Inc</pub><doi>10.1002/star.202100085</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-9996-8051</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0038-9056 |
ispartof | Starch - Stärke, 2021-09, Vol.73 (9-10), p.n/a |
issn | 0038-9056 1521-379X |
language | eng |
recordid | cdi_proquest_journals_2568186744 |
source | Wiley Online Library |
subjects | Carrageenan Cellulose cellulose nanocrystals Crystals Disintegration disintegration time Drying Fourier transforms Glycerol hard capsules Infrared analysis Infrared spectroscopy Nanocrystals oxidized rice starch Scanning electron microscopy Starch Tensile strength |
title | Preparation and Characterization of a Hard Capsule Based on Oxidized Rice Starch and Cellulose Nanocrystals |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T19%3A27%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Preparation%20and%20Characterization%20of%20a%20Hard%20Capsule%20Based%20on%20Oxidized%20Rice%20Starch%20and%20Cellulose%20Nanocrystals&rft.jtitle=Starch%20-%20St%C3%A4rke&rft.au=Chen,%20QiJie&rft.date=2021-09&rft.volume=73&rft.issue=9-10&rft.epage=n/a&rft.issn=0038-9056&rft.eissn=1521-379X&rft_id=info:doi/10.1002/star.202100085&rft_dat=%3Cproquest_cross%3E2568186744%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2568186744&rft_id=info:pmid/&rfr_iscdi=true |