Dietary EPA‐Enriched Phospholipids Alleviate Chronic Stress and LPS‐Induced Depression‐ and Anxiety‐Like Behavior by Regulating Immunity and Neuroinflammation

Scope A growing number of studies have reported the effects of eicosapentaenoic acid (EPA) and terrestrial phospholipids on ameliorating mood disorders. Marine‐derived EPA‐enriched phospholipids (EPA‐PL) exhibit the structural characteristics of EPA and phospholipids. However, the effect of dietary...

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Veröffentlicht in:	Molecular nutrition & food research 2021-09, Vol.65 (17), p.e2100009-n/a
Hauptverfasser:	Wang, Cheng‐Cheng, Du, Lei, Shi, Hao‐Hao, Ding, Lin, Yanagita, Teruyoshi, Xue, Chang‐Hu, Wang, Yu‐Ming, Zhang, Tian‐Tian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety Anxiety - chemically induced Anxiety - diet therapy Apoptosis Behavior, Animal - drug effects Brain - drug effects Brain - metabolism Brain - pathology Corticosterone - blood Depression - chemically induced Depression - diet therapy Diet Disease Models, Animal Disorders Eicosapentaenoic acid Eicosapentaenoic Acid - analogs & derivatives Eicosapentaenoic Acid - chemistry Eicosapentaenoic Acid - pharmacology Emotional disorders Enrichment Ethyl esters glial activation HPA axis Hypothalamic-pituitary-adrenal axis Hypothalamus Immunity Inflammation Kynurenine - metabolism Lipopolysaccharides Lipopolysaccharides - toxicity Male Mental depression Mice Mice, Inbred ICR monoamine systems Mood mood disorder Mood disorders Neuroinflammatory Diseases - diet therapy Neuroinflammatory Diseases - immunology Neuroinflammatory Diseases - physiopathology Neurotransmitter Agents - metabolism NLRP3 Phospholipids Phospholipids - chemistry Phospholipids - pharmacology Pituitary Spleen - drug effects Spleen - pathology Stress, Psychological - diet therapy Stress, Psychological - immunology T cell subpopulations Terrestrial environments
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