Recent Developments in Rodent Models of High-Fructose Diet-Induced Metabolic Syndrome: A Systematic Review
Metabolic syndrome (MetS) is the physiological clustering of hypertension, hyperglycemia, hyperinsulinemia, dyslipidemia, and insulin resistance. The MetS-related chronic illnesses encompass obesity, the cardiovascular system, renal operation, hepatic function, oncology, and mortality. To perform pr...
Gespeichert in:
| Veröffentlicht in: | Nutrients 2021-07, Vol.13 (8), p.2497, Article 2497 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 8 |
| container_start_page | 2497 |
| container_title | Nutrients |
| container_volume | 13 |
| creator | Chan, Alvin Man Lung Ng, Angela Min Hwei Mohd Yunus, Mohd Heikal Idrus, Ruszymah Bt Hj Law, Jia Xian Yazid, Muhammad Dain Chin, Kok-Yong Shamsuddin, Sharen Aini Lokanathan, Yogeswaran |
| description | Metabolic syndrome (MetS) is the physiological clustering of hypertension, hyperglycemia, hyperinsulinemia, dyslipidemia, and insulin resistance. The MetS-related chronic illnesses encompass obesity, the cardiovascular system, renal operation, hepatic function, oncology, and mortality. To perform pre-clinical research, it is imperative that these symptoms be successfully induced and optimized in lower taxonomy. Therefore, novel and future applications for a disease model, if proven valid, can be extrapolated to humans. MetS model establishment is evaluated based on the significance of selected test parameters, paradigm shifts from new discoveries, and the accessibility of the latest technology or advanced methodologies. Ultimately, the outcome of animal studies should be advantageous for human clinical trials and solidify their position in advanced medicine for clinicians to treat and adapt to serious or specific medical situations. Rodents (Rattus norvegicus and Mus musculus) have been ideal models for mammalian studies since the 18th century and have been mapped extensively. This review compiles and compares studies published in the past five years between the multitude of rodent comparative models. The response factors, niche parameters, and replicability of diet protocols are also compiled and analyzed to offer insight into MetS-related disease-specific modelling. |
| doi_str_mv | 10.3390/nu13082497 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_journals_2565480670</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A765644724</galeid><doaj_id>oai_doaj_org_article_ef99223641774486a46a187eb6ac6729</doaj_id><sourcerecordid>A765644724</sourcerecordid><originalsourceid>FETCH-LOGICAL-c516t-7b1aa041e363269bea4a2100ff4263e9c532ecfbf5b912da32ffde5d7858dc463</originalsourceid><addsrcrecordid>eNqNkk1v1DAQhiMEolXphV8QiQsCpfgrtsMBabWldKVWSAucLccZb71K7GInW_Xf47BVyyIOjA8zGj_z-kNvUbzG6IzSBn3wE6ZIEtaIZ8UxQYJUnDP6_I_6qDhNaYvmEEhw-rI4oiwHr-VxsV2DAT-W57CDPtwOuU6l8-U6dHP7Oqc-lcGWl25zU13EyYwhQXnuYKxWvpsMdOU1jLoNvTPlt3vfxTDAx3KR6zTCoMfcXsPOwd2r4oXVfYLTh3xS_Lj4_H15WV19_bJaLq4qU2M-VqLFWiOGgXJKeNOCZppghKxlhFNoTE0JGNvaum0w6TQl1nZQd0LWsjOM05Nitdftgt6q2-gGHe9V0E79boS4UTrma_WgwDYNIZQzLARjkmvGNZYCWq4NF6TJWp_2WrdTO0A3f1XU_YHo4Y53N2oTdkoyhAknWeDtg0AMPydIoxpcMtD32kOYkiI154hIjGf0zV_oNkzR56-aqZpJxAV6ojY6P8B5G_K5ZhZVC8FrzpggLFNn_6Dy6mBwJniwLvcPBt7tB0wMKUWwj2_ESM1GU09Gy_D7PXwHbbDJOPAGHgeyz7hspJR0thzOtPx_eunGbJngl2HyI_0Fp7_ijw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2565480670</pqid></control><display><type>article</type><title>Recent Developments in Rodent Models of High-Fructose Diet-Induced Metabolic Syndrome: A Systematic Review</title><source>Open Access: PubMed Central</source><source>PubMed Central Open Access</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /></source><source>EZB Electronic Journals Library</source><creator>Chan, Alvin Man Lung ; Ng, Angela Min Hwei ; Mohd Yunus, Mohd Heikal ; Idrus, Ruszymah Bt Hj ; Law, Jia Xian ; Yazid, Muhammad Dain ; Chin, Kok-Yong ; Shamsuddin, Sharen Aini ; Lokanathan, Yogeswaran</creator><creatorcontrib>Chan, Alvin Man Lung ; Ng, Angela Min Hwei ; Mohd Yunus, Mohd Heikal ; Idrus, Ruszymah Bt Hj ; Law, Jia Xian ; Yazid, Muhammad Dain ; Chin, Kok-Yong ; Shamsuddin, Sharen Aini ; Lokanathan, Yogeswaran</creatorcontrib><description>Metabolic syndrome (MetS) is the physiological clustering of hypertension, hyperglycemia, hyperinsulinemia, dyslipidemia, and insulin resistance. The MetS-related chronic illnesses encompass obesity, the cardiovascular system, renal operation, hepatic function, oncology, and mortality. To perform pre-clinical research, it is imperative that these symptoms be successfully induced and optimized in lower taxonomy. Therefore, novel and future applications for a disease model, if proven valid, can be extrapolated to humans. MetS model establishment is evaluated based on the significance of selected test parameters, paradigm shifts from new discoveries, and the accessibility of the latest technology or advanced methodologies. Ultimately, the outcome of animal studies should be advantageous for human clinical trials and solidify their position in advanced medicine for clinicians to treat and adapt to serious or specific medical situations. Rodents (Rattus norvegicus and Mus musculus) have been ideal models for mammalian studies since the 18th century and have been mapped extensively. This review compiles and compares studies published in the past five years between the multitude of rodent comparative models. The response factors, niche parameters, and replicability of diet protocols are also compiled and analyzed to offer insight into MetS-related disease-specific modelling.</description><identifier>ISSN: 2072-6643</identifier><identifier>EISSN: 2072-6643</identifier><identifier>DOI: 10.3390/nu13082497</identifier><identifier>PMID: 34444658</identifier><language>eng</language><publisher>BASEL: Mdpi</publisher><subject>Analysis ; Animal models ; Cardiovascular system ; Chronic diseases ; Chronic illnesses ; Clinical trials ; Clustering ; Cytokines ; Diabetes ; Diet ; Disease ; Dyslipidemia ; Fructose ; Genetic disorders ; Glucose ; Glycerol ; high fructose ; Hyperglycemia ; Hyperinsulinemia ; Hypertension ; Insulin ; Insulin resistance ; Life Sciences & Biomedicine ; Lifestyles ; Liver ; Medical research ; Medicine, Experimental ; Metabolic disorders ; Metabolic syndrome ; metabolic syndrome X ; Metabolites ; Narcotics ; Nutrition & Dietetics ; Obesity ; Osteoporosis ; rat ; Renal function ; Review ; rodent ; Rodents ; Science & Technology ; Signs and symptoms ; Socioeconomic factors ; syndrome X ; Systematic review ; Taxonomy ; Tumor necrosis factor-TNF ; Type 2 diabetes</subject><ispartof>Nutrients, 2021-07, Vol.13 (8), p.2497, Article 2497</ispartof><rights>COPYRIGHT 2021 MDPI AG</rights><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>34</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000689888300001</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c516t-7b1aa041e363269bea4a2100ff4263e9c532ecfbf5b912da32ffde5d7858dc463</citedby><cites>FETCH-LOGICAL-c516t-7b1aa041e363269bea4a2100ff4263e9c532ecfbf5b912da32ffde5d7858dc463</cites><orcidid>0000-0002-6793-2043 ; 0000-0001-9400-558X ; 0000-0001-6162-4405 ; 0000-0001-6628-1552 ; 0000-0001-9045-5145 ; 0000-0002-9548-6490</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401262/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401262/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27929,27930,39263,53796,53798</link.rule.ids></links><search><creatorcontrib>Chan, Alvin Man Lung</creatorcontrib><creatorcontrib>Ng, Angela Min Hwei</creatorcontrib><creatorcontrib>Mohd Yunus, Mohd Heikal</creatorcontrib><creatorcontrib>Idrus, Ruszymah Bt Hj</creatorcontrib><creatorcontrib>Law, Jia Xian</creatorcontrib><creatorcontrib>Yazid, Muhammad Dain</creatorcontrib><creatorcontrib>Chin, Kok-Yong</creatorcontrib><creatorcontrib>Shamsuddin, Sharen Aini</creatorcontrib><creatorcontrib>Lokanathan, Yogeswaran</creatorcontrib><title>Recent Developments in Rodent Models of High-Fructose Diet-Induced Metabolic Syndrome: A Systematic Review</title><title>Nutrients</title><addtitle>NUTRIENTS</addtitle><description>Metabolic syndrome (MetS) is the physiological clustering of hypertension, hyperglycemia, hyperinsulinemia, dyslipidemia, and insulin resistance. The MetS-related chronic illnesses encompass obesity, the cardiovascular system, renal operation, hepatic function, oncology, and mortality. To perform pre-clinical research, it is imperative that these symptoms be successfully induced and optimized in lower taxonomy. Therefore, novel and future applications for a disease model, if proven valid, can be extrapolated to humans. MetS model establishment is evaluated based on the significance of selected test parameters, paradigm shifts from new discoveries, and the accessibility of the latest technology or advanced methodologies. Ultimately, the outcome of animal studies should be advantageous for human clinical trials and solidify their position in advanced medicine for clinicians to treat and adapt to serious or specific medical situations. Rodents (Rattus norvegicus and Mus musculus) have been ideal models for mammalian studies since the 18th century and have been mapped extensively. This review compiles and compares studies published in the past five years between the multitude of rodent comparative models. The response factors, niche parameters, and replicability of diet protocols are also compiled and analyzed to offer insight into MetS-related disease-specific modelling.</description><subject>Analysis</subject><subject>Animal models</subject><subject>Cardiovascular system</subject><subject>Chronic diseases</subject><subject>Chronic illnesses</subject><subject>Clinical trials</subject><subject>Clustering</subject><subject>Cytokines</subject><subject>Diabetes</subject><subject>Diet</subject><subject>Disease</subject><subject>Dyslipidemia</subject><subject>Fructose</subject><subject>Genetic disorders</subject><subject>Glucose</subject><subject>Glycerol</subject><subject>high fructose</subject><subject>Hyperglycemia</subject><subject>Hyperinsulinemia</subject><subject>Hypertension</subject><subject>Insulin</subject><subject>Insulin resistance</subject><subject>Life Sciences & Biomedicine</subject><subject>Lifestyles</subject><subject>Liver</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Metabolic disorders</subject><subject>Metabolic syndrome</subject><subject>metabolic syndrome X</subject><subject>Metabolites</subject><subject>Narcotics</subject><subject>Nutrition & Dietetics</subject><subject>Obesity</subject><subject>Osteoporosis</subject><subject>rat</subject><subject>Renal function</subject><subject>Review</subject><subject>rodent</subject><subject>Rodents</subject><subject>Science & Technology</subject><subject>Signs and symptoms</subject><subject>Socioeconomic factors</subject><subject>syndrome X</subject><subject>Systematic review</subject><subject>Taxonomy</subject><subject>Tumor necrosis factor-TNF</subject><subject>Type 2 diabetes</subject><issn>2072-6643</issn><issn>2072-6643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>DOA</sourceid><recordid>eNqNkk1v1DAQhiMEolXphV8QiQsCpfgrtsMBabWldKVWSAucLccZb71K7GInW_Xf47BVyyIOjA8zGj_z-kNvUbzG6IzSBn3wE6ZIEtaIZ8UxQYJUnDP6_I_6qDhNaYvmEEhw-rI4oiwHr-VxsV2DAT-W57CDPtwOuU6l8-U6dHP7Oqc-lcGWl25zU13EyYwhQXnuYKxWvpsMdOU1jLoNvTPlt3vfxTDAx3KR6zTCoMfcXsPOwd2r4oXVfYLTh3xS_Lj4_H15WV19_bJaLq4qU2M-VqLFWiOGgXJKeNOCZppghKxlhFNoTE0JGNvaum0w6TQl1nZQd0LWsjOM05Nitdftgt6q2-gGHe9V0E79boS4UTrma_WgwDYNIZQzLARjkmvGNZYCWq4NF6TJWp_2WrdTO0A3f1XU_YHo4Y53N2oTdkoyhAknWeDtg0AMPydIoxpcMtD32kOYkiI154hIjGf0zV_oNkzR56-aqZpJxAV6ojY6P8B5G_K5ZhZVC8FrzpggLFNn_6Dy6mBwJniwLvcPBt7tB0wMKUWwj2_ESM1GU09Gy_D7PXwHbbDJOPAGHgeyz7hspJR0thzOtPx_eunGbJngl2HyI_0Fp7_ijw</recordid><startdate>20210722</startdate><enddate>20210722</enddate><creator>Chan, Alvin Man Lung</creator><creator>Ng, Angela Min Hwei</creator><creator>Mohd Yunus, Mohd Heikal</creator><creator>Idrus, Ruszymah Bt Hj</creator><creator>Law, Jia Xian</creator><creator>Yazid, Muhammad Dain</creator><creator>Chin, Kok-Yong</creator><creator>Shamsuddin, Sharen Aini</creator><creator>Lokanathan, Yogeswaran</creator><general>Mdpi</general><general>MDPI AG</general><general>MDPI</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-6793-2043</orcidid><orcidid>https://orcid.org/0000-0001-9400-558X</orcidid><orcidid>https://orcid.org/0000-0001-6162-4405</orcidid><orcidid>https://orcid.org/0000-0001-6628-1552</orcidid><orcidid>https://orcid.org/0000-0001-9045-5145</orcidid><orcidid>https://orcid.org/0000-0002-9548-6490</orcidid></search><sort><creationdate>20210722</creationdate><title>Recent Developments in Rodent Models of High-Fructose Diet-Induced Metabolic Syndrome: A Systematic Review</title><author>Chan, Alvin Man Lung ; Ng, Angela Min Hwei ; Mohd Yunus, Mohd Heikal ; Idrus, Ruszymah Bt Hj ; Law, Jia Xian ; Yazid, Muhammad Dain ; Chin, Kok-Yong ; Shamsuddin, Sharen Aini ; Lokanathan, Yogeswaran</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c516t-7b1aa041e363269bea4a2100ff4263e9c532ecfbf5b912da32ffde5d7858dc463</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Analysis</topic><topic>Animal models</topic><topic>Cardiovascular system</topic><topic>Chronic diseases</topic><topic>Chronic illnesses</topic><topic>Clinical trials</topic><topic>Clustering</topic><topic>Cytokines</topic><topic>Diabetes</topic><topic>Diet</topic><topic>Disease</topic><topic>Dyslipidemia</topic><topic>Fructose</topic><topic>Genetic disorders</topic><topic>Glucose</topic><topic>Glycerol</topic><topic>high fructose</topic><topic>Hyperglycemia</topic><topic>Hyperinsulinemia</topic><topic>Hypertension</topic><topic>Insulin</topic><topic>Insulin resistance</topic><topic>Life Sciences & Biomedicine</topic><topic>Lifestyles</topic><topic>Liver</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Metabolic disorders</topic><topic>Metabolic syndrome</topic><topic>metabolic syndrome X</topic><topic>Metabolites</topic><topic>Narcotics</topic><topic>Nutrition & Dietetics</topic><topic>Obesity</topic><topic>Osteoporosis</topic><topic>rat</topic><topic>Renal function</topic><topic>Review</topic><topic>rodent</topic><topic>Rodents</topic><topic>Science & Technology</topic><topic>Signs and symptoms</topic><topic>Socioeconomic factors</topic><topic>syndrome X</topic><topic>Systematic review</topic><topic>Taxonomy</topic><topic>Tumor necrosis factor-TNF</topic><topic>Type 2 diabetes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chan, Alvin Man Lung</creatorcontrib><creatorcontrib>Ng, Angela Min Hwei</creatorcontrib><creatorcontrib>Mohd Yunus, Mohd Heikal</creatorcontrib><creatorcontrib>Idrus, Ruszymah Bt Hj</creatorcontrib><creatorcontrib>Law, Jia Xian</creatorcontrib><creatorcontrib>Yazid, Muhammad Dain</creatorcontrib><creatorcontrib>Chin, Kok-Yong</creatorcontrib><creatorcontrib>Shamsuddin, Sharen Aini</creatorcontrib><creatorcontrib>Lokanathan, Yogeswaran</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 2021</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>Nutrients</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chan, Alvin Man Lung</au><au>Ng, Angela Min Hwei</au><au>Mohd Yunus, Mohd Heikal</au><au>Idrus, Ruszymah Bt Hj</au><au>Law, Jia Xian</au><au>Yazid, Muhammad Dain</au><au>Chin, Kok-Yong</au><au>Shamsuddin, Sharen Aini</au><au>Lokanathan, Yogeswaran</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recent Developments in Rodent Models of High-Fructose Diet-Induced Metabolic Syndrome: A Systematic Review</atitle><jtitle>Nutrients</jtitle><stitle>NUTRIENTS</stitle><date>2021-07-22</date><risdate>2021</risdate><volume>13</volume><issue>8</issue><spage>2497</spage><pages>2497-</pages><artnum>2497</artnum><issn>2072-6643</issn><eissn>2072-6643</eissn><abstract>Metabolic syndrome (MetS) is the physiological clustering of hypertension, hyperglycemia, hyperinsulinemia, dyslipidemia, and insulin resistance. The MetS-related chronic illnesses encompass obesity, the cardiovascular system, renal operation, hepatic function, oncology, and mortality. To perform pre-clinical research, it is imperative that these symptoms be successfully induced and optimized in lower taxonomy. Therefore, novel and future applications for a disease model, if proven valid, can be extrapolated to humans. MetS model establishment is evaluated based on the significance of selected test parameters, paradigm shifts from new discoveries, and the accessibility of the latest technology or advanced methodologies. Ultimately, the outcome of animal studies should be advantageous for human clinical trials and solidify their position in advanced medicine for clinicians to treat and adapt to serious or specific medical situations. Rodents (Rattus norvegicus and Mus musculus) have been ideal models for mammalian studies since the 18th century and have been mapped extensively. This review compiles and compares studies published in the past five years between the multitude of rodent comparative models. The response factors, niche parameters, and replicability of diet protocols are also compiled and analyzed to offer insight into MetS-related disease-specific modelling.</abstract><cop>BASEL</cop><pub>Mdpi</pub><pmid>34444658</pmid><doi>10.3390/nu13082497</doi><tpages>21</tpages><orcidid>https://orcid.org/0000-0002-6793-2043</orcidid><orcidid>https://orcid.org/0000-0001-9400-558X</orcidid><orcidid>https://orcid.org/0000-0001-6162-4405</orcidid><orcidid>https://orcid.org/0000-0001-6628-1552</orcidid><orcidid>https://orcid.org/0000-0001-9045-5145</orcidid><orcidid>https://orcid.org/0000-0002-9548-6490</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2072-6643 |
| ispartof | Nutrients, 2021-07, Vol.13 (8), p.2497, Article 2497 |
| issn | 2072-6643 2072-6643 |
| language | eng |
| recordid | cdi_proquest_journals_2565480670 |
| source | Open Access: PubMed Central; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" />; EZB Electronic Journals Library |
| subjects | Analysis Animal models Cardiovascular system Chronic diseases Chronic illnesses Clinical trials Clustering Cytokines Diabetes Diet Disease Dyslipidemia Fructose Genetic disorders Glucose Glycerol high fructose Hyperglycemia Hyperinsulinemia Hypertension Insulin Insulin resistance Life Sciences & Biomedicine Lifestyles Liver Medical research Medicine, Experimental Metabolic disorders Metabolic syndrome metabolic syndrome X Metabolites Narcotics Nutrition & Dietetics Obesity Osteoporosis rat Renal function Review rodent Rodents Science & Technology Signs and symptoms Socioeconomic factors syndrome X Systematic review Taxonomy Tumor necrosis factor-TNF Type 2 diabetes |
| title | Recent Developments in Rodent Models of High-Fructose Diet-Induced Metabolic Syndrome: A Systematic Review |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T18%3A04%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Recent%20Developments%20in%20Rodent%20Models%20of%20High-Fructose%20Diet-Induced%20Metabolic%20Syndrome:%20A%20Systematic%20Review&rft.jtitle=Nutrients&rft.au=Chan,%20Alvin%20Man%20Lung&rft.date=2021-07-22&rft.volume=13&rft.issue=8&rft.spage=2497&rft.pages=2497-&rft.artnum=2497&rft.issn=2072-6643&rft.eissn=2072-6643&rft_id=info:doi/10.3390/nu13082497&rft_dat=%3Cgale_proqu%3EA765644724%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2565480670&rft_id=info:pmid/34444658&rft_galeid=A765644724&rft_doaj_id=oai_doaj_org_article_ef99223641774486a46a187eb6ac6729&rfr_iscdi=true |