Muscle Plasticity under Functional Unloading: Effects of an Acid Sphingomyelinase Inhibitor Clomipramine

Sphingolipids function as both structural components of cells and intracellular messengers. The role of sphingolipids, including ceramide, in the regulation of muscle plasticity has not been studied. The present work aimed to study the effect of an inhibitor of the catalytic pathway of ceramide form...

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Veröffentlicht in:	Journal of evolutionary biochemistry and physiology 2021-07, Vol.57 (4), p.925-935
Hauptverfasser:	Sekunov, A. V., Protopopov, V. A., Skurygin, V. V., Shalagina, M. N., Bryndina, I. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animal Physiology Atrophy Biochemistry Biomedical and Life Sciences Ceramide Clomipramine Evolutionary Biology Experimental Papers Functional plasticity Immunofluorescence Isoforms Kinases Life Sciences Myosin Phenotypes Ribosomal protein S6 kinase Sphingolipids Sphingomyelin phosphodiesterase Thin-layer chromatography TOR protein Unloading Western blotting
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