The regulatory impact of RNA-binding proteins on microRNA targeting

Argonaute is the primary mediator of metazoan miRNA targeting (MT). Among the currently identified >1,500 human RNA-binding proteins (RBPs), there are only a handful of RBPs known to enhance MT and several others reported to suppress MT, leaving the global impact of RBPs on MT elusive. In this st...

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Veröffentlicht in:	Nature communications 2021-08, Vol.12 (1), p.5057-5057, Article 5057
Hauptverfasser:	Kim, Sukjun, Kim, Soyoung, Chang, Hee Ryung, Kim, Doyeon, Park, Junehee, Son, Narae, Park, Joori, Yoon, Minhyuk, Chae, Gwangung, Kim, Young-Kook, Kim, V. Narry, Kim, Yoon Ki, Nam, Jin-Wu, Shin, Chanseok, Baek, Daehyun
Format:	Artikel
Sprache:	eng
Schlagworte:	38 38/61 49/91 631/114/2114 631/208/200 631/337/1645 631/337/505 Binding sites Enhancers Humanities and Social Sciences MicroRNAs miRNA multidisciplinary Multidisciplinary Sciences Protein structure Proteins Ribonucleic acid RNA RNA-binding protein Science Science & Technology Science & Technology - Other Topics Science (multidisciplinary) Secondary structure Suppressors Transcriptomes
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