1210-P: Subcutaneous-Depot Specific Adiposity Change Is Associated with the Ectopic Fat Depot and Tissue Damage in High-Fat High-Sucrose (HFHS) Fed Fabp4 Cre-ERK2 Knockout Mice

Previous reports suggested that low subcutaneous adiposity increases the risk of cardiovascular events and diabetes. Mechanisms of depot-specific differences are still unknown. During studying tissue-specific roles of ERK2 (MAPK1), we observed Fabp4Cre mediated adipocyte-specific ERK2 knockout mice...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2021-06, Vol.70 (Supplement_1)
Hauptverfasser:	ISHINODA, YUKI, IDO, YASUO, NOGUCHI, MIDORI, YUMITA, YUSUKE, KAGAMI, KAZUKI, OSAKI, AYUMU, SATOH, YASUSHI, ENDO, SHOGO, KASUGA, AKIRA, ADACHI, TAKESHI, KUMAGAI, HIROO
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipogenesis Adipose tissue Body weight Cardiovascular diseases CRISPR Diabetes Diabetes mellitus Diet Extracellular signal-regulated kinase Fibrosis Insulin Kidneys Lipolysis Nucleotide sequence Oxygen consumption Phenotypes Sequence analysis Skeletal muscle Sucrose
Online-Zugang:	Volltext
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