1261-PUB: Type 2 Diabetes Mellitus Is an Independent Predictor of Hand Grip Strength in Patients with Established Cardiovascular Disease

Low hand grips strength (HGS), a validated parameter for poor skeletal muscular function, has been shown to be a predictor for mortality and cardiovascular events. Patients with established cardiovascular disease are at an increased risk of death and cardiovascular events, especially those who also...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2021-06, Vol.70 (Supplement_1)
Hauptverfasser:	LARCHER, BARBARA, VONBANK, ALEXANDER, MADER, ARTHUR, MAECHLER, MAXIMILIAN, SPRENGER, LUKAS, MUTSCHLECHNER, BEATRIX, LEIHERER, ANDREAS, MUENDLEIN, AXEL, DREXEL, HEINZ, SAELY, CHRISTOPH H.
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Sprache:	eng
Schlagworte:	Body height Cardiovascular disease Cardiovascular diseases Coronary artery Diabetes Diabetes mellitus (non-insulin dependent) Heart diseases Risk groups Vascular diseases
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creator	LARCHER, BARBARA VONBANK, ALEXANDER MADER, ARTHUR MAECHLER, MAXIMILIAN SPRENGER, LUKAS MUTSCHLECHNER, BEATRIX LEIHERER, ANDREAS MUENDLEIN, AXEL DREXEL, HEINZ SAELY, CHRISTOPH H.
description	Low hand grips strength (HGS), a validated parameter for poor skeletal muscular function, has been shown to be a predictor for mortality and cardiovascular events. Patients with established cardiovascular disease are at an increased risk of death and cardiovascular events, especially those who also have type 2 diabetes (T2DM). Factors predicting HGS in this important population are unclear and are therefore addressed in the present study. We investigated a high-risk cohort of 874 patients with established cardiovascular disease, including 670 patients with angiographically verified coronary artery disease and 204 patients with sonographically verified peripheral artery disease. From our patients, 274 (31.4%) had T2DM according to ADA criteria. In analysis of covariance, the presence of T2DM significantly predicted higher HGS (F 8.8; p=0.003); further predictors of higher HGS were younger age (F=206.8; p
doi_str_mv	10.2337/db21-1261-PUB
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Patients with established cardiovascular disease are at an increased risk of death and cardiovascular events, especially those who also have type 2 diabetes (T2DM). Factors predicting HGS in this important population are unclear and are therefore addressed in the present study. We investigated a high-risk cohort of 874 patients with established cardiovascular disease, including 670 patients with angiographically verified coronary artery disease and 204 patients with sonographically verified peripheral artery disease. From our patients, 274 (31.4%) had T2DM according to ADA criteria. In analysis of covariance, the presence of T2DM significantly predicted higher HGS (F 8.8; p=0.003); further predictors of higher HGS were younger age (F=206.8; p<0.001), male sex (F 176.7; p<0.001), and greater body height (F= 77.1; p<0.001). 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We conclude that the presence of T2DM is a predictor of higher HGS in high-risk patients with established CVD.</description><subject>Body height</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Coronary artery</subject><subject>Diabetes</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Heart diseases</subject><subject>Risk groups</subject><subject>Vascular diseases</subject><issn>0012-1797</issn><issn>1939-327X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNo1kF1LwzAUhoMoOKeX3ge8ruajTRrvdM5tMHHgBO_CaZO6jNrWJFX2D_zZdkw5cA68PJwXHoQuKblmnMsbUzCaUCZosnq9P0IjqrhKOJNvx2hECGUJlUqeorMQtoQQMcwI_fzzt3i96yxm-MFBYaMN-MnWtYt9wIuAocGLxtjODquJeOWtcWVsPW4rPIfG4Jl3HX6J3jbvcYNdg1cQ3YAG_O2GYBoiFLULG2vwBLxx7ReEsq_BD33BQrDn6KSCOtiLvztG68fpejJPls-zxeRumZRC8IQbkudpLpiieQEmNarMaAE0J4aqNMskoaCyShoCRliQFS-BytRwI40qSMbH6OrwtvPtZ29D1Nu2983QqFkmGBMZp3ygkgNV-jYEbyvdefcBfqcp0XvXeu9a793pwR3_BX1ZcYw</recordid><startdate>20210601</startdate><enddate>20210601</enddate><creator>LARCHER, BARBARA</creator><creator>VONBANK, ALEXANDER</creator><creator>MADER, ARTHUR</creator><creator>MAECHLER, MAXIMILIAN</creator><creator>SPRENGER, LUKAS</creator><creator>MUTSCHLECHNER, BEATRIX</creator><creator>LEIHERER, ANDREAS</creator><creator>MUENDLEIN, AXEL</creator><creator>DREXEL, HEINZ</creator><creator>SAELY, CHRISTOPH H.</creator><general>American Diabetes Association</general><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20210601</creationdate><title>1261-PUB: Type 2 Diabetes Mellitus Is an Independent Predictor of Hand Grip Strength in Patients with Established Cardiovascular Disease</title><author>LARCHER, BARBARA ; VONBANK, ALEXANDER ; MADER, ARTHUR ; MAECHLER, MAXIMILIAN ; SPRENGER, LUKAS ; MUTSCHLECHNER, BEATRIX ; LEIHERER, ANDREAS ; MUENDLEIN, AXEL ; DREXEL, HEINZ ; SAELY, CHRISTOPH H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c663-3d0884862918bad4d9c51ba180d19455701a95f7d0ad6ea7f3ca174d3d7d9b053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Body height</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular diseases</topic><topic>Coronary artery</topic><topic>Diabetes</topic><topic>Diabetes mellitus (non-insulin dependent)</topic><topic>Heart diseases</topic><topic>Risk groups</topic><topic>Vascular diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LARCHER, BARBARA</creatorcontrib><creatorcontrib>VONBANK, ALEXANDER</creatorcontrib><creatorcontrib>MADER, ARTHUR</creatorcontrib><creatorcontrib>MAECHLER, MAXIMILIAN</creatorcontrib><creatorcontrib>SPRENGER, LUKAS</creatorcontrib><creatorcontrib>MUTSCHLECHNER, BEATRIX</creatorcontrib><creatorcontrib>LEIHERER, ANDREAS</creatorcontrib><creatorcontrib>MUENDLEIN, AXEL</creatorcontrib><creatorcontrib>DREXEL, HEINZ</creatorcontrib><creatorcontrib>SAELY, CHRISTOPH H.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Diabetes (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LARCHER, BARBARA</au><au>VONBANK, ALEXANDER</au><au>MADER, ARTHUR</au><au>MAECHLER, MAXIMILIAN</au><au>SPRENGER, LUKAS</au><au>MUTSCHLECHNER, BEATRIX</au><au>LEIHERER, ANDREAS</au><au>MUENDLEIN, AXEL</au><au>DREXEL, HEINZ</au><au>SAELY, CHRISTOPH H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>1261-PUB: Type 2 Diabetes Mellitus Is an Independent Predictor of Hand Grip Strength in Patients with Established Cardiovascular Disease</atitle><jtitle>Diabetes (New York, N.Y.)</jtitle><date>2021-06-01</date><risdate>2021</risdate><volume>70</volume><issue>Supplement_1</issue><issn>0012-1797</issn><eissn>1939-327X</eissn><abstract>Low hand grips strength (HGS), a validated parameter for poor skeletal muscular function, has been shown to be a predictor for mortality and cardiovascular events. Patients with established cardiovascular disease are at an increased risk of death and cardiovascular events, especially those who also have type 2 diabetes (T2DM). Factors predicting HGS in this important population are unclear and are therefore addressed in the present study. We investigated a high-risk cohort of 874 patients with established cardiovascular disease, including 670 patients with angiographically verified coronary artery disease and 204 patients with sonographically verified peripheral artery disease. From our patients, 274 (31.4%) had T2DM according to ADA criteria. In analysis of covariance, the presence of T2DM significantly predicted higher HGS (F 8.8; p=0.003); further predictors of higher HGS were younger age (F=206.8; p<0.001), male sex (F 176.7; p<0.001), and greater body height (F= 77.1; p<0.001). 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subjects	Body height Cardiovascular disease Cardiovascular diseases Coronary artery Diabetes Diabetes mellitus (non-insulin dependent) Heart diseases Risk groups Vascular diseases
title	1261-PUB: Type 2 Diabetes Mellitus Is an Independent Predictor of Hand Grip Strength in Patients with Established Cardiovascular Disease
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