Monolithic polymeric porous superhydrophobic material with pneumatic plastron stabilization for functionally durable drag reduction in blood-contacting biomedical applications
Superhydrophobic (SHP) surfaces can provide substantial reductions in flow drag forces and reduce blood damage in cardiovascular medical devices. However, strategies for functional durability are necessary, as many SHP surfaces have low durability under abrasion or strong fluid jetting or eventually...
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| creator | Marlena, Jennifer Tan, Justin Kok Soon Lin, Zenggan Li, David Xinzheyang Zhao, Boxin Leo, Hwa Liang Kim, Sangho Yap, Choon Hwai |
| description | Superhydrophobic (SHP) surfaces can provide substantial reductions in flow drag forces and reduce blood damage in cardiovascular medical devices. However, strategies for functional durability are necessary, as many SHP surfaces have low durability under abrasion or strong fluid jetting or eventually lose their air plastron and slip-flow capabilities due to plastron gas dissolution, high fluid pressure, or fouling. Here, we present a functional material that extends the functional durability of superhydrophobic slip flow. Facile modification of a porous superhydrophobic polytetrafluoroethylene (PTFE, Teflon) foam produced suitable surface structures to enable fluid slip flow and resist protein fouling. Its monolithic nature offered abrasion durability, while its porosity allowed pressurized air to be supplied to resist fluid impalement and to replenish the air plastron lost to the fluid through dissolution. Active pore pressure control could resist high fluid pressures and turbulent flow conditions across a wide range of applied pressures. The pneumatically stabilized material yielded large drag reductions (up to 50%) even with protein fouling, as demonstrated from high-speed water jetting and closed loop pressure drop tests. Coupled with its high hemocompatibility and impaired protein adsorption, this easily fabricated material can be viable for incorporation into blood-contacting medical devices.
Facile modification of a porous superhydrophobic polytetrafluoroethylene foam produced suitable surface structures to enable fluid slip flow and resist protein fouling. Its monolithic nature offered abrasion durability, while its porosity allowed pressurized air to be supplied to resist fluid impalement and to replenish the air plastron lost to the fluid. Active pore pressure control could resist high fluid pressures and turbulent flow conditions across a wide range of applied pressures. The pneumatically stabilized material yielded large drag reductions even with protein fouling. Coupled with its high hemocompatibility, this easily fabricated material can be viable for incorporation into blood-contacting medical devices. |
| doi_str_mv | 10.1038/s41427-021-00325-9 |
| format | Article |
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Facile modification of a porous superhydrophobic polytetrafluoroethylene foam produced suitable surface structures to enable fluid slip flow and resist protein fouling. Its monolithic nature offered abrasion durability, while its porosity allowed pressurized air to be supplied to resist fluid impalement and to replenish the air plastron lost to the fluid. Active pore pressure control could resist high fluid pressures and turbulent flow conditions across a wide range of applied pressures. The pneumatically stabilized material yielded large drag reductions even with protein fouling. Coupled with its high hemocompatibility, this easily fabricated material can be viable for incorporation into blood-contacting medical devices.</description><identifier>ISSN: 1884-4049</identifier><identifier>EISSN: 1884-4057</identifier><identifier>DOI: 10.1038/s41427-021-00325-9</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>639/166/985 ; 639/301/54/990 ; Active control ; Aerodynamics ; Biomaterials ; Biomedical materials ; Blood ; Chemistry and Materials Science ; Closed loops ; Dissolution ; Drag ; Drag reduction ; Drop tests ; Durability ; Energy Systems ; Fluid dynamics ; Fluid flow ; Fluid pressure ; Fouling ; Hydrophobic surfaces ; Hydrophobicity ; Impact tests ; Materials Science ; Medical electronics ; Medical equipment ; Optical and Electronic Materials ; Polytetrafluoroethylene ; Porosity ; Porous materials ; Pressure drop ; Proteins ; Slip flow ; Structural Materials ; Surface and Interface Science ; Thin Films ; Turbulent flow</subject><ispartof>NPG Asia materials, 2021-08, Vol.13 (1), Article 58</ispartof><rights>The Author(s) 2021</rights><rights>The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c363t-2a3e7808579e1c5382aaac891fb9da224477148c90bd7d893946157eeb0ce6fd3</citedby><cites>FETCH-LOGICAL-c363t-2a3e7808579e1c5382aaac891fb9da224477148c90bd7d893946157eeb0ce6fd3</cites><orcidid>0000-0003-2918-3077</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/s41427-021-00325-9$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://doi.org/10.1038/s41427-021-00325-9$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,860,27901,27902,41096,42165,51551</link.rule.ids></links><search><creatorcontrib>Marlena, Jennifer</creatorcontrib><creatorcontrib>Tan, Justin Kok Soon</creatorcontrib><creatorcontrib>Lin, Zenggan</creatorcontrib><creatorcontrib>Li, David Xinzheyang</creatorcontrib><creatorcontrib>Zhao, Boxin</creatorcontrib><creatorcontrib>Leo, Hwa Liang</creatorcontrib><creatorcontrib>Kim, Sangho</creatorcontrib><creatorcontrib>Yap, Choon Hwai</creatorcontrib><title>Monolithic polymeric porous superhydrophobic material with pneumatic plastron stabilization for functionally durable drag reduction in blood-contacting biomedical applications</title><title>NPG Asia materials</title><addtitle>NPG Asia Mater</addtitle><description>Superhydrophobic (SHP) surfaces can provide substantial reductions in flow drag forces and reduce blood damage in cardiovascular medical devices. However, strategies for functional durability are necessary, as many SHP surfaces have low durability under abrasion or strong fluid jetting or eventually lose their air plastron and slip-flow capabilities due to plastron gas dissolution, high fluid pressure, or fouling. Here, we present a functional material that extends the functional durability of superhydrophobic slip flow. Facile modification of a porous superhydrophobic polytetrafluoroethylene (PTFE, Teflon) foam produced suitable surface structures to enable fluid slip flow and resist protein fouling. Its monolithic nature offered abrasion durability, while its porosity allowed pressurized air to be supplied to resist fluid impalement and to replenish the air plastron lost to the fluid through dissolution. Active pore pressure control could resist high fluid pressures and turbulent flow conditions across a wide range of applied pressures. The pneumatically stabilized material yielded large drag reductions (up to 50%) even with protein fouling, as demonstrated from high-speed water jetting and closed loop pressure drop tests. Coupled with its high hemocompatibility and impaired protein adsorption, this easily fabricated material can be viable for incorporation into blood-contacting medical devices.
Facile modification of a porous superhydrophobic polytetrafluoroethylene foam produced suitable surface structures to enable fluid slip flow and resist protein fouling. Its monolithic nature offered abrasion durability, while its porosity allowed pressurized air to be supplied to resist fluid impalement and to replenish the air plastron lost to the fluid. Active pore pressure control could resist high fluid pressures and turbulent flow conditions across a wide range of applied pressures. The pneumatically stabilized material yielded large drag reductions even with protein fouling. Coupled with its high hemocompatibility, this easily fabricated material can be viable for incorporation into blood-contacting medical devices.</description><subject>639/166/985</subject><subject>639/301/54/990</subject><subject>Active control</subject><subject>Aerodynamics</subject><subject>Biomaterials</subject><subject>Biomedical materials</subject><subject>Blood</subject><subject>Chemistry and Materials Science</subject><subject>Closed loops</subject><subject>Dissolution</subject><subject>Drag</subject><subject>Drag reduction</subject><subject>Drop tests</subject><subject>Durability</subject><subject>Energy Systems</subject><subject>Fluid dynamics</subject><subject>Fluid flow</subject><subject>Fluid pressure</subject><subject>Fouling</subject><subject>Hydrophobic surfaces</subject><subject>Hydrophobicity</subject><subject>Impact tests</subject><subject>Materials Science</subject><subject>Medical electronics</subject><subject>Medical equipment</subject><subject>Optical and Electronic Materials</subject><subject>Polytetrafluoroethylene</subject><subject>Porosity</subject><subject>Porous materials</subject><subject>Pressure drop</subject><subject>Proteins</subject><subject>Slip flow</subject><subject>Structural Materials</subject><subject>Surface and Interface Science</subject><subject>Thin Films</subject><subject>Turbulent flow</subject><issn>1884-4049</issn><issn>1884-4057</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>BENPR</sourceid><recordid>eNp9UctOwzAQjBBIVKU_wMkS54Bfie0jqnhJRVzgbDm206Zy42AnQuGn-EWcBsGN087OzuxqNVl2ieA1goTfRIooZjnEKIeQ4CIXJ9kCcU5zCgt2-oupOM9WMe4hhKgsKS_oIvt69q13Tb9rNOi8Gw82HFHwQwRx6GzYjSb4buerxB9Un-bKgY_kAF1rh8RMeqdiH3wLYq-qxjWfiU1d7QOoh1ZPjXJuBGYIqnIWmKC2IFgzHEegaUHlvDe59m2vEtduQdX4gzWNTsdU17kEJmm8yM5q5aJd_dRl9nZ_97p-zDcvD0_r202uSUn6HCtiGYe8YMIiXRCOlVKaC1RXwiiMKWUMUa4FrAwzXBBBS1QwayuobVkbssyu5r1d8O-Djb3c-yGkL6LERQkpp0ywpMKzSgcfY7C17EJzUGGUCMopGzlnI1M28piNFMlEZlNM4nZrw9_qf1zfaPKYHQ</recordid><startdate>20210813</startdate><enddate>20210813</enddate><creator>Marlena, Jennifer</creator><creator>Tan, Justin Kok Soon</creator><creator>Lin, Zenggan</creator><creator>Li, David Xinzheyang</creator><creator>Zhao, Boxin</creator><creator>Leo, Hwa Liang</creator><creator>Kim, Sangho</creator><creator>Yap, Choon Hwai</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><orcidid>https://orcid.org/0000-0003-2918-3077</orcidid></search><sort><creationdate>20210813</creationdate><title>Monolithic polymeric porous superhydrophobic material with pneumatic plastron stabilization for functionally durable drag reduction in blood-contacting biomedical applications</title><author>Marlena, Jennifer ; 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However, strategies for functional durability are necessary, as many SHP surfaces have low durability under abrasion or strong fluid jetting or eventually lose their air plastron and slip-flow capabilities due to plastron gas dissolution, high fluid pressure, or fouling. Here, we present a functional material that extends the functional durability of superhydrophobic slip flow. Facile modification of a porous superhydrophobic polytetrafluoroethylene (PTFE, Teflon) foam produced suitable surface structures to enable fluid slip flow and resist protein fouling. Its monolithic nature offered abrasion durability, while its porosity allowed pressurized air to be supplied to resist fluid impalement and to replenish the air plastron lost to the fluid through dissolution. Active pore pressure control could resist high fluid pressures and turbulent flow conditions across a wide range of applied pressures. The pneumatically stabilized material yielded large drag reductions (up to 50%) even with protein fouling, as demonstrated from high-speed water jetting and closed loop pressure drop tests. Coupled with its high hemocompatibility and impaired protein adsorption, this easily fabricated material can be viable for incorporation into blood-contacting medical devices.
Facile modification of a porous superhydrophobic polytetrafluoroethylene foam produced suitable surface structures to enable fluid slip flow and resist protein fouling. Its monolithic nature offered abrasion durability, while its porosity allowed pressurized air to be supplied to resist fluid impalement and to replenish the air plastron lost to the fluid. Active pore pressure control could resist high fluid pressures and turbulent flow conditions across a wide range of applied pressures. The pneumatically stabilized material yielded large drag reductions even with protein fouling. Coupled with its high hemocompatibility, this easily fabricated material can be viable for incorporation into blood-contacting medical devices.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><doi>10.1038/s41427-021-00325-9</doi><orcidid>https://orcid.org/0000-0003-2918-3077</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | 639/166/985 639/301/54/990 Active control Aerodynamics Biomaterials Biomedical materials Blood Chemistry and Materials Science Closed loops Dissolution Drag Drag reduction Drop tests Durability Energy Systems Fluid dynamics Fluid flow Fluid pressure Fouling Hydrophobic surfaces Hydrophobicity Impact tests Materials Science Medical electronics Medical equipment Optical and Electronic Materials Polytetrafluoroethylene Porosity Porous materials Pressure drop Proteins Slip flow Structural Materials Surface and Interface Science Thin Films Turbulent flow |
| title | Monolithic polymeric porous superhydrophobic material with pneumatic plastron stabilization for functionally durable drag reduction in blood-contacting biomedical applications |
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