Curcumin Loaded PEGylated Nanoemulsions Designed for Maintained Antioxidant Effects and Improved Bioavailability: A Pilot Study on Rats

The current study describes the experimental design guided development of PEGylated nanoemulsions as parenteral delivery systems for curcumin, a powerful antioxidant, as well as the evaluation of their physicochemical characteristics and antioxidant activity during the two years of storage. Experime...

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Veröffentlicht in:	International journal of molecular sciences 2021-08, Vol.22 (15), p.7991
Hauptverfasser:	Đoković, Jelena B., Savić, Sanela M., Mitrović, Jelena R., Nikolic, Ines, Marković, Bojan D., Randjelović, Danijela V., Antic-Stankovic, Jelena, Božić, Dragana, Cekić, Nebojša D., Stevanović, Vladimir, Batinić, Bojan, Aranđelović, Jovana, Savić, Miroslav M., Savić, Snežana D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Antioxidants Bioavailability Curcumin Design of experiments Drug delivery systems Intravenous administration Investigations Nanoemulsions Pharmacokinetics Phospholipids Polydispersity Quality management Room temperature Soybeans Vegetable oils Viscosity Zeta potential
Online-Zugang:	Volltext
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