An autopsy case of PARK2 due to a homozygous exon 2 deletion of parkin and associated with α‐synucleinopathy

Lewy bodies (LBs) are usually detected in patients with idiopathic Parkinson's disease (PD), but there have been few reports of LBs in a familial form of early‐onset PD associated with several mutations in parkin, a gene that encodes a ubiquitin E3 ligase involved in mitochondrial homeostasis,...

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Veröffentlicht in:Neuropathology 2021-08, Vol.41 (4), p.293-300
Hauptverfasser: Sakuwa, Mayuko, Adachi, Tadashi, Yoshida, Kentaro, Adachi, Yoshiki, Nakano, Toshiya, Hanajima, Ritsuko
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Sprache:eng
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