Evaluation of cyrhetrenyl and ferrocenyl precursors as 5-lipoxygenase inhibitors - biological and computational studies

A series of ferrocenyl and cyrhetrenyl complexes [(η 5 -C 5 H 4 R)ML n ] (ML n = [(η 5 -C 5 H 5 Fe) ( 1 ); ML n = Re(CO) 3 ( 2 )) with R = H ( 1a ; 2a ), R = aldehyde ( 1b ; 2b ), R = carboxylic acid ( 1c ; 2c ), and R = amino ( 1d ; 2d ) were synthesized. A new synthetic route was reported to obtai...

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Veröffentlicht in:	New journal of chemistry 2021-08, Vol.45 (3), p.1336-13368
Hauptverfasser:	Muñoz-Osses, Michelle, Quiroz, Javiera, Vásquez-Martínez, Yesseny, Flores, Erick, Navarrete, Elizabeth, Godoy, Fernando, Torrent, Claudia, Cortez-San Martín, Marcelo, Gómez, Alejandra, Mascayano, Carolina
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Aldehydes Antioxidants Arachidonic acid Biological computing Carboxylic acids Molecular docking Molecular dynamics Precursors Reagents Scavenging Substrates
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