Single nucleotide translation without ribosomes

The translation of messenger RNA sequences into polypeptide sequences according to the genetic code is central to life. How this process, which relies on the ribosomal machinery, arose from much simpler precursors is unclear. Here, we demonstrate that single nucleotides charged with an amino acid co...

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Veröffentlicht in:	Nature chemistry 2021-08, Vol.13 (8), p.751-757
Hauptverfasser:	Jash, Biswarup, Tremmel, Peter, Jovanovic, Dejana, Richert, Clemens
Format:	Artikel
Sprache:	eng
Schlagworte:	639/638/45/500 639/638/904 Amino acids Analytical Chemistry Aqueous solutions Biochemistry Chemistry Chemistry and Materials Science Chemistry/Food Science Gene sequencing Genetic code Inorganic Chemistry mRNA Nucleotide sequence Nucleotides Organic Chemistry Physical Chemistry Polypeptides Ribonucleic acid Ribosomes RNA Translation
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