Angiotensin‐converting enzyme inhibitor prevents skeletal muscle fibrosis in diabetic mice

New Findings What is the central question of this study? We questioned whether an angiotensin‐converting enzyme (ACE) inhibitor prevents skeletal muscle fibrosis in diabetic mice. What is the main finding and its importance? Administration of ACE inhibitor prevents the increase in skeletal muscle fi...

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Veröffentlicht in:	Experimental physiology 2021-08, Vol.106 (8), p.1785-1793
Hauptverfasser:	Kakutani, Naoya, Takada, Shingo, Nambu, Hideo, Maekawa, Satoshi, Hagiwara, Hikaru, Yamanashi, Katsuma, Obata, Yoshikuni, Nakano, Ippei, Fumoto, Yoshizuki, Hata, Soichiro, Furihata, Takaaki, Fukushima, Arata, Yokota, Takashi, Kinugawa, Shintaro
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin Angiotensin-Converting Enzyme Inhibitors - pharmacology Angiotensin-Converting Enzyme Inhibitors - therapeutic use angiotensin‐converting enzyme inhibitor Animals Antihypertensive Agents - pharmacology Antihypertensives Collagen Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - drug therapy Enzymes Extracellular matrix Fibrosis Mice Muscle function Muscle, Skeletal Musculoskeletal system Myocardial infarction Physical activity Rats Rodents Skeletal muscle Streptozocin Therapeutic targets
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