Synthesis and Cytotoxicity of Lupane Mono- and Bis-Piperazinylamides

Mono- and bis-piperazinylamides of lupane acids and their derivatives modified on ring A were synthesized and tested for cytotoxicity. Cytotoxicity studies against nine different human tumor cells found that betulonic acid N -methylpiperazinylamide inhibited the growth of SR leukemia, NCI-H460 non-s...

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Veröffentlicht in:	Chemistry of natural compounds 2021-07, Vol.57 (4), p.698-705
Hauptverfasser:	Giniyatullina, G. V., Kazakova, O. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides Cancer Chemistry Chemistry and Materials Science Chemistry/Food Science Colon Colon cancer Cytotoxicity Hydrazones Leukemia Lung cancer, Non-small cell Organic Chemistry Plant Sciences Rings (mathematics) Toxicity testing
Online-Zugang:	Volltext
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