Correlation of frontal atrophy with behavioral changes in amyotrophic lateral sclerosis

Background Recent studies have linked cognitive impairment in amyotrophic lateral sclerosis to frontotemporal pathology. Aim We examined possible associations between behavior changes and regional gray matter volume in early amyotrophic lateral sclerosis, and assessed whether the volume changes were...

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Veröffentlicht in:	Neurology and clinical neuroscience 2016-05, Vol.4 (3), p.85-92
Hauptverfasser:	Terada, Tatsuhiro, Obi, Tomokazu, Miyata, Jun, Kubota, Manabu, Yoshizumi, Miho, Murai, Toshiya, Yamazaki, Kinya, Mizoguchi, Kouichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Atrophy Behavior Behavior rating scales Cognitive ability Emotional behavior Frontal lobe Frontal Systems Behavior Scale Magnetic resonance imaging Morphometry motor impairment respiratory failure Respiratory function Substantia grisea voxel‐based morphometry
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