The crosstalk between DRP1-dependent mitochondrial fission and oxidative stress triggers hepatocyte apoptosis induced by silver nanoparticles

Previous studies have revealed that the liver is the main target organ of deposition for engineered nanoparticles. The hepatotoxicity of silver nanoparticles (AgNPs), the widely used antimicrobial nanoparticles, has been of great interest. However, little is known about the regulatory mechanism of t...

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Veröffentlicht in:	Nanoscale 2021-07, Vol.13 (28), p.12356-12369
Hauptverfasser:	Li, Jiangyan, Chang, Xiaoru, Shang, Mengting, Niu, Shuyan, Zhang, Wenli, Li, Yunjing, Sun, Zuoyi, Wu, Tianshu, Kong, Lu, Zhang, Ting, Tang, Meng, Xue, Yuying
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiinfectives and antibacterials Apoptosis Crosstalk Damage Fission Homology Kinases Liver Mitochondria Nanoparticles Oxidative stress Regulatory mechanisms (biology) Silver
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