P03.23 Evolution of the immune landscape within partially controlled murine melanoma

BackgroundRegulatory T cell (Treg) depletion with antibodies against CD25 is effective in tumor models but response rates are low in poorly infiltrated B16 melanomas. Combination with a tumor vaccine enhances efficacy, but relapse usually occurs following partial control, similar to what is seen cli...

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Veröffentlicht in:Journal for immunotherapy of cancer 2020-10, Vol.8 (Suppl 2), p.A31-A32
Hauptverfasser: Qing, C, Ghorani, E, Solomon, I, Gálvez-Cancino, F, Vargas, F, Peggs, K, Quezada, S
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Sprache:eng
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