Multimodal Treatment With Doxorubicin, Cisplatin, and Ifosfamide for the Treatment of Advanced or Metastatic Uterine Leiomyosarcoma: A Unicentric Experience

OBJECTIVEUterine leiomyosarcoma (ULMS) is a rare gynecologic malignancy characterized by a poor prognosis due to a high rate of local and metastatic recurrences. Chemotherapy with doxorubicin or ifosfamide or both is associated with a 10% to 30% objective response rate. We report a monocentric exper...

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Veröffentlicht in:	International journal of gynecological cancer 2015-02, Vol.25 (2), p.296-302
Hauptverfasser:	Hadoux, Julien, Rey, Annie, Duvillard, Pierre, Lhommé, Catherine, Balleyguier, Corinne, Haie-Meder, Christine, Morice, Philippe, Tazi, Youssef, Leary, Alexandra, Larue, Christine, Pautier, Patricia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic Combined Chemotherapy Protocols - therapeutic use Catheter Ablation Chemotherapy Cisplatin - administration & dosage Cisplatin - adverse effects Combined Modality Therapy Disease Progression Doxorubicin - administration & dosage Doxorubicin - adverse effects Female Gynecologic Surgical Procedures Humans Ifosfamide - administration & dosage Ifosfamide - adverse effects Leiomyosarcoma - drug therapy Leiomyosarcoma - mortality Leiomyosarcoma - pathology Leiomyosarcoma - therapy Medical prognosis Metastasis Middle Aged Neoplasm Metastasis Neutropenia Radiotherapy, Adjuvant Response rates Retrospective Studies Survival Analysis Uterine Neoplasms - drug therapy Uterine Neoplasms - mortality Uterine Neoplasms - pathology Uterine Neoplasms - therapy
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