Anti-Inflammatory Activity of Melatonin: a Focus on the Role of NLRP3 Inflammasome

Melatonin is a hormone of the pineal gland that contributes to the regulation of physiological activities, such as sleep, circadian rhythm, and neuroendocrine processes. Melatonin is found in several plants and has pharmacological activities including antioxidant, anti-inflammatory, hepatoprotective...

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Veröffentlicht in:	Inflammation 2021-08, Vol.44 (4), p.1207-1222
Hauptverfasser:	Ashrafizadeh, Milad, Najafi, Masoud, Kavyiani, Nasim, Mohammadinejad, Reza, Farkhondeh, Tahereh, Samarghandian, Saeed
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-inflammatory agents Anti-Inflammatory Agents - pharmacology Antioxidants Antioxidants - metabolism Antioxidants - pharmacology Biomedical and Life Sciences Biomedicine Caspase-1 Circadian rhythms Diabetes Diabetes mellitus Humans IL-1β Immunology Inflammasomes Inflammasomes - antagonists & inhibitors Inflammasomes - metabolism Inflammation Inflammation Mediators - antagonists & inhibitors Inflammation Mediators - metabolism Internal Medicine Melatonin Melatonin - metabolism Melatonin - pharmacology miRNA Neurological diseases Neuroprotection NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors NLR Family, Pyrin Domain-Containing 3 Protein - metabolism Non-coding RNA Pathology Pharmacology/Toxicology Pineal gland Pyroptosis Review Rheumatology SIRT1 protein Wnt protein Wnt Signaling Pathway - drug effects Wnt Signaling Pathway - physiology β-Catenin
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