Highly selective two-photon fluorescent off-on probes for imaging tyrosinase activity in living cells and tissues

Highly selective two-photon fluorescent off-on probes for imaging tyrosinase activity in living cells and tissues

A coumarin-based two-photon (TP) fluorescent off-on probe has been developed for detecting tyrosinase activity. High selectivity, sensitivity and biocompatibility enable the probes to successfully image tyrosinase activity in live cells and tissues using TP microscopy. A two-photon fluorescent probe...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2021-07, Vol.57 (56), p.6911-6914
Hauptverfasser: Cui, Yixin, Park, Sang Jun, Wu, Xiaofeng, Wang, Rui, Qi, Sujie, Kim, Hwan Myung, Yoon, Juyoung
Format: Artikel
Sprache:eng
Schlagworte:
Biocompatibility
Chemistry
Chemistry, Multidisciplinary
Coumarin
Fluorescence
Photons
Physical Sciences
Science & Technology
Selectivity
Tyrosinase
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Beschreibung
Zusammenfassung:A coumarin-based two-photon (TP) fluorescent off-on probe has been developed for detecting tyrosinase activity. High selectivity, sensitivity and biocompatibility enable the probes to successfully image tyrosinase activity in live cells and tissues using TP microscopy. A two-photon fluorescent probe with high selectivity and sensitivity has been developed and applied to image tyrosinase activity in cells and tissues.
ISSN:1359-7345
1364-548X
DOI:10.1039/d1cc02374h