Few vertebrate species dominate the Borrelia burgdorferi s.l. life cycle
Background. In the northern hemisphere, ticks of the Ixodidae family are vectors of diseases such as Lyme borreliosis, Rocky Mountain spotted fever and tick-borne encephalitis. Most of these ticks are generalists and have a three-host life cycle for which they are dependent on three different hosts...
Gespeichert in:
| Veröffentlicht in: | Environmental research letters 2016-04, Vol.11 (4), p.43001-43016 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 43016 |
|---|---|
| container_issue | 4 |
| container_start_page | 43001 |
| container_title | Environmental research letters |
| container_volume | 11 |
| creator | Hofmeester, T R Coipan, E C van Wieren, S E Prins, H H T Takken, W Sprong, H |
| description | Background. In the northern hemisphere, ticks of the Ixodidae family are vectors of diseases such as Lyme borreliosis, Rocky Mountain spotted fever and tick-borne encephalitis. Most of these ticks are generalists and have a three-host life cycle for which they are dependent on three different hosts for their blood meal. Finding out which host species contribute most in maintaining ticks and the pathogens they transmit, is imperative in understanding the drivers behind the dynamics of a disease. Methods. We performed a systematic review to identify the most important vertebrate host species for Ixodes ricinus and Borrelia burgdorferi s.l. as a well-studied model system for tick-borne diseases. We analyzed data from 66 publications and quantified the relative contribution for 15 host species. Review results. We found a positive correlation between host body mass and tick burdens for the different stages of I. ricinus. We show that nymphal burdens of host species are positively correlated with infection prevalence with B. burgdorferi s.l., which is again positively correlated with the realized reservoir competence of a host species for B. burgdorferi s.l. Our quantification method suggests that only a few host species, which are amongst the most widespread species in the environment (rodents, thrushes and deer), feed the majority of I. ricinus individuals and that rodents infect the majority of I. ricinus larvae with B. burgdorferi s.l. Discussion. We argue that small mammal-transmitted Borrelia spp. are maintained due to the high density of their reservoir hosts, while bird-transmitted Borrelia spp. are maintained due to the high infection prevalence of their reservoir hosts. Our findings suggest that Ixodes ricinus and Borrelia burgdorferi s.l. populations are maintained by a few widespread host species. The increase in distribution and abundance of these species, could be the cause for the increase in Lyme borreliosis incidence in Europe in recent decades. |
| doi_str_mv | 10.1088/1748-9326/11/4/043001 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2549227661</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_d4c368aede34431495ac9944e58d369d</doaj_id><sourcerecordid>2549227661</sourcerecordid><originalsourceid>FETCH-LOGICAL-c593t-bd3bd06f68f2a26daf1f5802dbc8632c232713b161160f1b214219e184b047113</originalsourceid><addsrcrecordid>eNp9kUFv1DAQhSMEEqXwE5AicYDL7npsx7G5QUVppUpc4Gw59mTxyhsHO2HVf4_ToLaqEBePNXrv08y8qnoLZAtEyh20XG4Uo2IHsOM7whkh8Kw6u-8_f_R_Wb3K-UBIw5tWnlVXl3iqf2OasEtmwjqPaD3m2sWjH5bG9BPrzzElDN7U3Zz2LqYek6_zNmzr4Hus7a0N-Lp60ZuQ8c3fel79uPzy_eJqc_Pt6_XFp5uNbRSbNp1jnSOiF7KnhgpneugbSajrrBSMWspoC6wDASBIDx0FTkEhSN4R3gKw8-p65bpoDnpM_mjSrY7G67tGTHtt0uTLRNpxy4Q06JBxzoCrxlilOMdGOiaUK6yPK-tk9jj4oTx6MMn6fAcMvtykwE9z0kNYyjh3WTeEiZYV84fVPKb4a8Y86aPPFkMwA8Y5a5BECqVaoor03RPpIc5pKGfStOGK0laIZbNmVdkUc07Y328HRC9B6yVEvYSoATTXa9DF9371-Tg-gDGFxyo9ur4o4R_K_9P_AH1rtb0</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2549227661</pqid></control><display><type>article</type><title>Few vertebrate species dominate the Borrelia burgdorferi s.l. life cycle</title><source>Institute of Physics IOPscience extra</source><source>IOP Publishing Free Content</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Free Full-Text Journals in Chemistry</source><creator>Hofmeester, T R ; Coipan, E C ; van Wieren, S E ; Prins, H H T ; Takken, W ; Sprong, H</creator><creatorcontrib>Hofmeester, T R ; Coipan, E C ; van Wieren, S E ; Prins, H H T ; Takken, W ; Sprong, H</creatorcontrib><description>Background. In the northern hemisphere, ticks of the Ixodidae family are vectors of diseases such as Lyme borreliosis, Rocky Mountain spotted fever and tick-borne encephalitis. Most of these ticks are generalists and have a three-host life cycle for which they are dependent on three different hosts for their blood meal. Finding out which host species contribute most in maintaining ticks and the pathogens they transmit, is imperative in understanding the drivers behind the dynamics of a disease. Methods. We performed a systematic review to identify the most important vertebrate host species for Ixodes ricinus and Borrelia burgdorferi s.l. as a well-studied model system for tick-borne diseases. We analyzed data from 66 publications and quantified the relative contribution for 15 host species. Review results. We found a positive correlation between host body mass and tick burdens for the different stages of I. ricinus. We show that nymphal burdens of host species are positively correlated with infection prevalence with B. burgdorferi s.l., which is again positively correlated with the realized reservoir competence of a host species for B. burgdorferi s.l. Our quantification method suggests that only a few host species, which are amongst the most widespread species in the environment (rodents, thrushes and deer), feed the majority of I. ricinus individuals and that rodents infect the majority of I. ricinus larvae with B. burgdorferi s.l. Discussion. We argue that small mammal-transmitted Borrelia spp. are maintained due to the high density of their reservoir hosts, while bird-transmitted Borrelia spp. are maintained due to the high infection prevalence of their reservoir hosts. Our findings suggest that Ixodes ricinus and Borrelia burgdorferi s.l. populations are maintained by a few widespread host species. The increase in distribution and abundance of these species, could be the cause for the increase in Lyme borreliosis incidence in Europe in recent decades.</description><identifier>ISSN: 1748-9326</identifier><identifier>EISSN: 1748-9326</identifier><identifier>DOI: 10.1088/1748-9326/11/4/043001</identifier><identifier>CODEN: ERLNAL</identifier><language>eng</language><publisher>Bristol: IOP Publishing</publisher><subject>016-3926 ; Arachnids ; Bacterial diseases ; Body mass ; Borrelia ; Borrelia burgdorferi ; Borreliosis ; Correlation ; deer ; Encephalitis ; Geographical distribution ; Herbivores ; Infections ; Ixodes ricinus ; Ixodidae ; Larvae ; Life cycles ; Lyme borreliosis ; Mountains ; Northern Hemisphere ; Parasitic diseases ; Rocky Mountain spotted fever ; Rodents ; small mammals ; Species ; thrushes ; Tick-borne diseases ; Tick-borne encephalitis ; Ticks ; transmission maintenance ; Vectors ; Vertebrates</subject><ispartof>Environmental research letters, 2016-04, Vol.11 (4), p.43001-43016</ispartof><rights>2016 IOP Publishing Ltd</rights><rights>2016. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Wageningen University & Research</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c593t-bd3bd06f68f2a26daf1f5802dbc8632c232713b161160f1b214219e184b047113</citedby><cites>FETCH-LOGICAL-c593t-bd3bd06f68f2a26daf1f5802dbc8632c232713b161160f1b214219e184b047113</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://iopscience.iop.org/article/10.1088/1748-9326/11/4/043001/pdf$$EPDF$$P50$$Giop$$Hfree_for_read</linktopdf><link.rule.ids>230,314,776,780,860,881,2096,27901,27902,38845,38867,53815,53842</link.rule.ids></links><search><creatorcontrib>Hofmeester, T R</creatorcontrib><creatorcontrib>Coipan, E C</creatorcontrib><creatorcontrib>van Wieren, S E</creatorcontrib><creatorcontrib>Prins, H H T</creatorcontrib><creatorcontrib>Takken, W</creatorcontrib><creatorcontrib>Sprong, H</creatorcontrib><title>Few vertebrate species dominate the Borrelia burgdorferi s.l. life cycle</title><title>Environmental research letters</title><addtitle>ERL</addtitle><addtitle>Environ. Res. Lett</addtitle><description>Background. In the northern hemisphere, ticks of the Ixodidae family are vectors of diseases such as Lyme borreliosis, Rocky Mountain spotted fever and tick-borne encephalitis. Most of these ticks are generalists and have a three-host life cycle for which they are dependent on three different hosts for their blood meal. Finding out which host species contribute most in maintaining ticks and the pathogens they transmit, is imperative in understanding the drivers behind the dynamics of a disease. Methods. We performed a systematic review to identify the most important vertebrate host species for Ixodes ricinus and Borrelia burgdorferi s.l. as a well-studied model system for tick-borne diseases. We analyzed data from 66 publications and quantified the relative contribution for 15 host species. Review results. We found a positive correlation between host body mass and tick burdens for the different stages of I. ricinus. We show that nymphal burdens of host species are positively correlated with infection prevalence with B. burgdorferi s.l., which is again positively correlated with the realized reservoir competence of a host species for B. burgdorferi s.l. Our quantification method suggests that only a few host species, which are amongst the most widespread species in the environment (rodents, thrushes and deer), feed the majority of I. ricinus individuals and that rodents infect the majority of I. ricinus larvae with B. burgdorferi s.l. Discussion. We argue that small mammal-transmitted Borrelia spp. are maintained due to the high density of their reservoir hosts, while bird-transmitted Borrelia spp. are maintained due to the high infection prevalence of their reservoir hosts. Our findings suggest that Ixodes ricinus and Borrelia burgdorferi s.l. populations are maintained by a few widespread host species. The increase in distribution and abundance of these species, could be the cause for the increase in Lyme borreliosis incidence in Europe in recent decades.</description><subject>016-3926</subject><subject>Arachnids</subject><subject>Bacterial diseases</subject><subject>Body mass</subject><subject>Borrelia</subject><subject>Borrelia burgdorferi</subject><subject>Borreliosis</subject><subject>Correlation</subject><subject>deer</subject><subject>Encephalitis</subject><subject>Geographical distribution</subject><subject>Herbivores</subject><subject>Infections</subject><subject>Ixodes ricinus</subject><subject>Ixodidae</subject><subject>Larvae</subject><subject>Life cycles</subject><subject>Lyme borreliosis</subject><subject>Mountains</subject><subject>Northern Hemisphere</subject><subject>Parasitic diseases</subject><subject>Rocky Mountain spotted fever</subject><subject>Rodents</subject><subject>small mammals</subject><subject>Species</subject><subject>thrushes</subject><subject>Tick-borne diseases</subject><subject>Tick-borne encephalitis</subject><subject>Ticks</subject><subject>transmission maintenance</subject><subject>Vectors</subject><subject>Vertebrates</subject><issn>1748-9326</issn><issn>1748-9326</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>O3W</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNp9kUFv1DAQhSMEEqXwE5AicYDL7npsx7G5QUVppUpc4Gw59mTxyhsHO2HVf4_ToLaqEBePNXrv08y8qnoLZAtEyh20XG4Uo2IHsOM7whkh8Kw6u-8_f_R_Wb3K-UBIw5tWnlVXl3iqf2OasEtmwjqPaD3m2sWjH5bG9BPrzzElDN7U3Zz2LqYek6_zNmzr4Hus7a0N-Lp60ZuQ8c3fel79uPzy_eJqc_Pt6_XFp5uNbRSbNp1jnSOiF7KnhgpneugbSajrrBSMWspoC6wDASBIDx0FTkEhSN4R3gKw8-p65bpoDnpM_mjSrY7G67tGTHtt0uTLRNpxy4Q06JBxzoCrxlilOMdGOiaUK6yPK-tk9jj4oTx6MMn6fAcMvtykwE9z0kNYyjh3WTeEiZYV84fVPKb4a8Y86aPPFkMwA8Y5a5BECqVaoor03RPpIc5pKGfStOGK0laIZbNmVdkUc07Y328HRC9B6yVEvYSoATTXa9DF9371-Tg-gDGFxyo9ur4o4R_K_9P_AH1rtb0</recordid><startdate>20160401</startdate><enddate>20160401</enddate><creator>Hofmeester, T R</creator><creator>Coipan, E C</creator><creator>van Wieren, S E</creator><creator>Prins, H H T</creator><creator>Takken, W</creator><creator>Sprong, H</creator><general>IOP Publishing</general><scope>O3W</scope><scope>TSCCA</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>L6V</scope><scope>M7S</scope><scope>PATMY</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PKEHL</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>7QL</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope><scope>QVL</scope><scope>DOA</scope></search><sort><creationdate>20160401</creationdate><title>Few vertebrate species dominate the Borrelia burgdorferi s.l. life cycle</title><author>Hofmeester, T R ; Coipan, E C ; van Wieren, S E ; Prins, H H T ; Takken, W ; Sprong, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c593t-bd3bd06f68f2a26daf1f5802dbc8632c232713b161160f1b214219e184b047113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>016-3926</topic><topic>Arachnids</topic><topic>Bacterial diseases</topic><topic>Body mass</topic><topic>Borrelia</topic><topic>Borrelia burgdorferi</topic><topic>Borreliosis</topic><topic>Correlation</topic><topic>deer</topic><topic>Encephalitis</topic><topic>Geographical distribution</topic><topic>Herbivores</topic><topic>Infections</topic><topic>Ixodes ricinus</topic><topic>Ixodidae</topic><topic>Larvae</topic><topic>Life cycles</topic><topic>Lyme borreliosis</topic><topic>Mountains</topic><topic>Northern Hemisphere</topic><topic>Parasitic diseases</topic><topic>Rocky Mountain spotted fever</topic><topic>Rodents</topic><topic>small mammals</topic><topic>Species</topic><topic>thrushes</topic><topic>Tick-borne diseases</topic><topic>Tick-borne encephalitis</topic><topic>Ticks</topic><topic>transmission maintenance</topic><topic>Vectors</topic><topic>Vertebrates</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hofmeester, T R</creatorcontrib><creatorcontrib>Coipan, E C</creatorcontrib><creatorcontrib>van Wieren, S E</creatorcontrib><creatorcontrib>Prins, H H T</creatorcontrib><creatorcontrib>Takken, W</creatorcontrib><creatorcontrib>Sprong, H</creatorcontrib><collection>IOP Publishing Free Content</collection><collection>IOPscience (Open Access)</collection><collection>CrossRef</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Engineering Collection</collection><collection>Engineering Database</collection><collection>Environmental Science Database</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>NARCIS:Publications</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Environmental research letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hofmeester, T R</au><au>Coipan, E C</au><au>van Wieren, S E</au><au>Prins, H H T</au><au>Takken, W</au><au>Sprong, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Few vertebrate species dominate the Borrelia burgdorferi s.l. life cycle</atitle><jtitle>Environmental research letters</jtitle><stitle>ERL</stitle><addtitle>Environ. Res. Lett</addtitle><date>2016-04-01</date><risdate>2016</risdate><volume>11</volume><issue>4</issue><spage>43001</spage><epage>43016</epage><pages>43001-43016</pages><issn>1748-9326</issn><eissn>1748-9326</eissn><coden>ERLNAL</coden><abstract>Background. In the northern hemisphere, ticks of the Ixodidae family are vectors of diseases such as Lyme borreliosis, Rocky Mountain spotted fever and tick-borne encephalitis. Most of these ticks are generalists and have a three-host life cycle for which they are dependent on three different hosts for their blood meal. Finding out which host species contribute most in maintaining ticks and the pathogens they transmit, is imperative in understanding the drivers behind the dynamics of a disease. Methods. We performed a systematic review to identify the most important vertebrate host species for Ixodes ricinus and Borrelia burgdorferi s.l. as a well-studied model system for tick-borne diseases. We analyzed data from 66 publications and quantified the relative contribution for 15 host species. Review results. We found a positive correlation between host body mass and tick burdens for the different stages of I. ricinus. We show that nymphal burdens of host species are positively correlated with infection prevalence with B. burgdorferi s.l., which is again positively correlated with the realized reservoir competence of a host species for B. burgdorferi s.l. Our quantification method suggests that only a few host species, which are amongst the most widespread species in the environment (rodents, thrushes and deer), feed the majority of I. ricinus individuals and that rodents infect the majority of I. ricinus larvae with B. burgdorferi s.l. Discussion. We argue that small mammal-transmitted Borrelia spp. are maintained due to the high density of their reservoir hosts, while bird-transmitted Borrelia spp. are maintained due to the high infection prevalence of their reservoir hosts. Our findings suggest that Ixodes ricinus and Borrelia burgdorferi s.l. populations are maintained by a few widespread host species. The increase in distribution and abundance of these species, could be the cause for the increase in Lyme borreliosis incidence in Europe in recent decades.</abstract><cop>Bristol</cop><pub>IOP Publishing</pub><doi>10.1088/1748-9326/11/4/043001</doi><tpages>16</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1748-9326 |
| ispartof | Environmental research letters, 2016-04, Vol.11 (4), p.43001-43016 |
| issn | 1748-9326 1748-9326 |
| language | eng |
| recordid | cdi_proquest_journals_2549227661 |
| source | Institute of Physics IOPscience extra; IOP Publishing Free Content; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry |
| subjects | 016-3926 Arachnids Bacterial diseases Body mass Borrelia Borrelia burgdorferi Borreliosis Correlation deer Encephalitis Geographical distribution Herbivores Infections Ixodes ricinus Ixodidae Larvae Life cycles Lyme borreliosis Mountains Northern Hemisphere Parasitic diseases Rocky Mountain spotted fever Rodents small mammals Species thrushes Tick-borne diseases Tick-borne encephalitis Ticks transmission maintenance Vectors Vertebrates |
| title | Few vertebrate species dominate the Borrelia burgdorferi s.l. life cycle |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T18%3A42%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Few%20vertebrate%20species%20dominate%20the%20Borrelia%20burgdorferi%20s.l.%20life%20cycle&rft.jtitle=Environmental%20research%20letters&rft.au=Hofmeester,%20T%20R&rft.date=2016-04-01&rft.volume=11&rft.issue=4&rft.spage=43001&rft.epage=43016&rft.pages=43001-43016&rft.issn=1748-9326&rft.eissn=1748-9326&rft.coden=ERLNAL&rft_id=info:doi/10.1088/1748-9326/11/4/043001&rft_dat=%3Cproquest_cross%3E2549227661%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2549227661&rft_id=info:pmid/&rft_doaj_id=oai_doaj_org_article_d4c368aede34431495ac9944e58d369d&rfr_iscdi=true |