A fluorometric and optical signal dual-readout detection of alkaline phosphatase activity in living cells based on ATP-mediated porphyrin MOFs

[Display omitted] •For the first time, nanoscale chiral MOFs was developed to quantitatively detect ALP activity in living cells.•Fluorometric and optical signal dual-readout mode detection system showed ultrasensitive detection of ALP activity.•The detection limit was was significantly lower than t...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2021-09, Vol.342, p.130017, Article 130017
Hauptverfasser:	Song, Yanxia, Lu, Siyu, Sun, Shihao, Guo, Wenting, Su, Junxia, Meng, Genping, Hai, Jun, Wang, Baodui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Alkaline phosphatase Biomarkers Cells (biology) Chiral metal-organic framework Circular dichroism Dichroism Fluorescence Living cells Metal-organic frameworks Optical communication Phosphatase Porphyrin Porphyrins Selectivity
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