In Vitro Models for Studying Entry, Tissue Tropism, and Therapeutic Approaches of Highly Pathogenic Coronaviruses

Coronaviruses (CoVs) are enveloped nonsegmented positive-sense RNA viruses belonging to the family Coronaviridae that contain the largest genome among RNA viruses. Their genome encodes 4 major structural proteins, and among them, the Spike (S) protein plays a crucial role in determining the viral tr...

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Veröffentlicht in:	BioMed research international 2021, Vol.2021, p.1-21, Article 8856018
Hauptverfasser:	Najafi Fard, Saeid, Petrone, Linda, Petruccioli, Elisa, Alonzi, Tonino, Matusali, Giulia, Colavita, Francesca, Castilletti, Concetta, Capobianchi, Maria Rosaria, Goletti, Delia
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Antiviral agents Biological models Biomedical research Biotechnology & Applied Microbiology Care and treatment Cell fusion Cell lines Coronavirus infections Coronaviruses COVID-19 Development and progression Disease transmission Genetic aspects Genomes Glycoproteins Health aspects Host-virus relationships Infections Life cycles Life Sciences & Biomedicine Medical research Medicine, Experimental Medicine, Research & Experimental Methods Middle East respiratory syndrome Pathogenesis Physiological aspects Proteins Research & Experimental Medicine Respiratory diseases Review RNA viruses Science & Technology Severe acute respiratory syndrome coronavirus 2 Structural proteins Tropism Tropisms Virus attachment Virus research Viruses Zoonoses
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