PGE2 displays immunosuppressive effects during human active tuberculosis

Prostaglandin E2 (PGE2), an active lipid compound derived from arachidonic acid, regulates different stages of the immune response of the host during several pathologies such as chronic infections or cancer. In fact, manipulation of PGE2 levels was proposed as an approach for countering the Type I I...

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Veröffentlicht in:	Scientific reports 2021-06, Vol.11 (1), p.13559-14, Article 13559
Hauptverfasser:	Pellegrini, Joaquín Miguel, Martin, Candela, Morelli, María Paula, Schander, Julieta Aylen, Tateosian, Nancy Liliana, Amiano, Nicolás Oscar, Rolandelli, Agustín, Palmero, Domingo Juan, Levi, Alberto, Ciallella, Lorena, Colombo, María Isabel, García, Verónica Edith
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/2499 631/250/255/1856 Adult Antigens Arachidonic acid Autophagy Cytokines Dinoprostone - immunology Dinoprostone - pharmacology Female Humanities and Social Sciences Humans Immune response Immunosuppressive Agents - immunology Immunosuppressive Agents - pharmacology Inflammation Interferon Leukocytes (neutrophilic) Male Monocytes Monocytes - immunology multidisciplinary Mycobacterium tuberculosis - immunology Neutrophils - immunology Phagocytosis Prostaglandin E2 Science Science (multidisciplinary) Tuberculosis Tuberculosis - immunology
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